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Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus.

16 Dec 2022

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Cleft lip and palate are among the most common congenital malformations, which are mainly due to genetic causes.

16 Dec 2022

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Researchers from the Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered a novel subtype of Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and EBV-associated immunosuppression in the tumor microenvironment (TME).

16 Dec 2022

Natural substances show great therapeutic potential to inhibit influenza viruses

Fever, cough, sore throat, and general malaise - the cold season is here, and not only corona but also influenza viruses are spreading again at a rapid pace.

16 Dec 2022

Ceramide blockers prevent the loss of muscle mass during aging in mice

During aging, mice, like humans, become inactive and lose muscle mass and strength. A team of scientists led by Johan Auwerx at EPFL have now discovered that when mice age, their muscles become packed with ceramides.

16 Dec 2022

Using synthetic gene circuits to better control the timing of immunotherapy

In two separate studies, researchers demonstrate how synthetic biology can be used to tackle a difficult issue in cancer immunotherapy: the way immunotherapy-related approaches focused on short-term killing of tumor cells may fail to eradicate tumors because growth of tumors happens on longer timescales.

16 Dec 2022

New chemical compound shows promise to reverse effects of potentially deadly drugs

Drug overdoses in the United States have risen sharply in the last two decades. Nearly 92,000 people died from overdoses of illegal drugs and prescription opioids in 2020-;more than five times the number of deaths in the year 2000-;and synthetic opioids like fentanyl are one of the main culprits.

16 Dec 2022

Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

Scientists identify an immunogenic epitope at the furin cleavage site of the SARS-CoV-2 spike protein.

15 Dec 2022

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this “starvation response” is triggered, and what can inhibit it.

15 Dec 2022

Researchers unravel the molecular mechanisms of steatosis-to-NASH progression

The global prevalence of nonalcoholic fatty liver disease (NAFLD) is estimated to be > 25% and will continue to rise.

15 Dec 2022

Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Researchers from the Neurobiology of miRNA team coordinated by Davide De Pietri Tonelli at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) has discovered the correlation between a class of small RNA molecules, piRNAs, and brain inflammation.

15 Dec 2022

Study discovers four genes linked to increased risk of suicidal thoughts and behaviors

A large study of military members led by researchers at Duke Health and the Durham VA identified four genes that are linked to an increased risk of suicidal thoughts and behaviors.

15 Dec 2022

Researchers discover how segmentation clock genes instruct the tempo of spine formation

One of the most dramatic phases of fetal development occurs as previously unstructured collections of rapidly dividing precursor cells begin forming the embryo's spine.

15 Dec 2022

Radical project aims to develop a new method for commercial production of anti-microbial peptides

THE COVID pandemic has revealed just how delicate our public health is in terms of overcoming infectious diseases and antimicrobial resistance.

15 Dec 2022

Edible plant-based ink could reduce the cost of cultured meat production

Cultured meat (also known as cell-based or lab-grown meat) is a promising, more environmentally friendly alternative to meat produced from traditional livestock farming.

15 Dec 2022

Novel experimental system traces the development and longevity of plasma cells

Just as a fire department mobilizes in response to a reported fire, specialized immune cells in the body mobilize in response to the introduction of foreign substances known as antigens.

15 Dec 2022

Scientists uncover how FoxH1 factor binds to specific points in the genome

Transcription factors are proteins that interact with DNA to regulate the function of some genes. Generally, a single transcription factor binds to several regions in the genome as it orchestrates complex cellular responses, which require the activation or inhibition of several genes.

15 Dec 2022

Life Science News

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Natural substances show great therapeutic potential to inhibit influenza viruses

Ceramide blockers prevent the loss of muscle mass during aging in mice

Using synthetic gene circuits to better control the timing of immunotherapy

New chemical compound shows promise to reverse effects of potentially deadly drugs

Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Researchers unravel the molecular mechanisms of steatosis-to-NASH progression

Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Study discovers four genes linked to increased risk of suicidal thoughts and behaviors

Researchers discover how segmentation clock genes instruct the tempo of spine formation

Radical project aims to develop a new method for commercial production of anti-microbial peptides

Edible plant-based ink could reduce the cost of cultured meat production

Novel experimental system traces the development and longevity of plasma cells

Scientists uncover how FoxH1 factor binds to specific points in the genome

Extraordinary plasticity of the glucocorticoid receptor revealed

Tiny messenger can be promising candidate for treatment of diseases associated with muscular atrophy

Study reveals limited effects of longevity treatments on the aging process

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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