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Researchers use loop-seq technology to decipher the mechanical code of DNA

A new study has deciphered the mechanical code of DNA to reveal previously unknown ways in which nature encodes biological information in DNA sequence.

5 Dec 2022

Hepatitis B virus haplotype number is a predictive marker of functional cure during antiviral therapies

Patients with a lower hepatitis B virus haplotype number are more likely to achieve a functional cure with chronic hepatitis B treatment.

4 Dec 2022

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases.

4 Dec 2022

Sharp increase in B cell population can prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing.

2 Dec 2022

New Collaborative Research Center investigates how Treg cells influence immunological and tissue-specific diseases

The German Research Foundation (DFG) has approved the establishment and funding of the Collaborative Research Center/Transregio (CRC/TRR) 355 "Heterogeneity and functional specialization of regulatory T cells in distinct microenvironments".

2 Dec 2022

CRC 1361 at JGU continues to achieve excellence in DNA repair and genome stability research

The German Research Foundation (DFG) announced the prolongation of the Collaborative Research Center (CRC) 1361: "Regulation of DNA Repair and Genome Stability" for an additional four years.

2 Dec 2022

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Our kidney filters 180 liters of blood every day and retains nutrients through a process called 'endocytosis' and through active transport in the kidney cells.

2 Dec 2022

Collaborative work unravels hidden molecular secrets of age-related diseases

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, and the University of Copenhagen announced today the release of the first batch of results from the collaborative work directed to perform multi-omics-based analyses in the context of age-related diseases using an AI-driven target and drug discovery pipeline.

2 Dec 2022

Scaling up the production of customized immune cells for drug development and testing

To prevent testing on animals and create even more precise ways of testing therapeutics, the pharmaceutical industry is increasingly turning to human immune cells.

1 Dec 2022

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Residue from rinse agents is left behind on dishes after they are cleaned in professional-grade dishwashers.

1 Dec 2022

Using cationic nanonmaterials to target visceral adiposity

Researchers have long been working on how to treat obesity, a serious condition that can lead to hypertension, diabetes, chronic inflammation, and cardiovascular diseases.

1 Dec 2022

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Ketamine, an established anesthetic and increasingly popular antidepressant, dramatically reorganizes activity in the brain, as if a switch had been flipped on its active circuits, according to a new study by Penn Medicine researchers.

1 Dec 2022

Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.

1 Dec 2022

Research shows biological sex as a crucial factor in the effectiveness of anti-aging drugs

The effect of medicines on women and men can differ significantly. This also applies to the currently most promising anti-aging drug rapamycin, as researchers from the Max Planck Institute for Biology of Ageing in Cologne and University College London have now shown.

1 Dec 2022

New metagenomic study reveals global landscape of antimicrobial resistance

There are large geographical differences in both how frequently resistant genes occur and in which types of bacteria the genes are found.

1 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.

1 Dec 2022

Study implicates a specific type of brain cell as key player underlying the impact of stressors

More than 70% of adults will experience at least one traumatic experience, such as a life-threatening illness or accident, violent assault or natural disaster, in their lifetimes and nearly a third will experience four or more, according to global data.

1 Dec 2022

Early life experiences can affect gene activity more than half a lifetime later

Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers.

1 Dec 2022

Metrion Biosciences invests in new High Throughput Screening capability and expanded facilities

Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research and drug discovery company, today announced the launch of its High Throughput Screening (HTS) capability, as well as the expansion of its state-of-the-art lab and office facilities. Scott Maidment has been appointed as Head of HTS to lead the new service.

From Metrion Biosciences Limited 1 Dec 2022

Life Science News

Researchers use loop-seq technology to decipher the mechanical code of DNA

Hepatitis B virus haplotype number is a predictive marker of functional cure during antiviral therapies

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Sharp increase in B cell population can prevent intestinal healing

New Collaborative Research Center investigates how Treg cells influence immunological and tissue-specific diseases

CRC 1361 at JGU continues to achieve excellence in DNA repair and genome stability research

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Collaborative work unravels hidden molecular secrets of age-related diseases

Scaling up the production of customized immune cells for drug development and testing

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Using cationic nanonmaterials to target visceral adiposity

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Research shows biological sex as a crucial factor in the effectiveness of anti-aging drugs

New metagenomic study reveals global landscape of antimicrobial resistance

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Study implicates a specific type of brain cell as key player underlying the impact of stressors

Early life experiences can affect gene activity more than half a lifetime later

Metrion Biosciences invests in new High Throughput Screening capability and expanded facilities

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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