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UCD researchers discover gene mutation linked to vision problems in zebrafish

Researchers in University College Dublin (UCD) have discovered that a mutation in a gene called emc1 causes major vision problems in zebrafish.

8 Jan 2025

New research reframes the debate on drug development costs

The typical cost of developing new medications may not be as high as generally believed, with a few ultra-costly medications skewing public discussions about the cost of pharmaceutical research and development, according to a new RAND study.

8 Jan 2025

AI-designed drug shows promise for inflammatory bowel disease

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announces positive results from two Phase I studies in Australia and China of ISM5411, a novel gut-restricted and PHD specific Inhibitor designed and optimized with the support of Insilico's Chemistry42 commercially-available generative reinforcement learning platform, for Inflammatory Bowel Disease (IBD).

8 Jan 2025

Innovative AI approach enhances imaging in thick biological samples

Depth degradation is a problem biologists know all too well: The deeper you look into a sample, the fuzzier the image becomes.

7 Jan 2025

Nuclear lipid droplets could play a key role in aging and disease

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled "Nuclear lipid droplets: a novel regulator of nuclear homeostasis and aging."

7 Jan 2025

Study reveals neutrophils' dynamic role in cancer progression

Neutrophils are the most abundant white blood cells in the human body, primarily recognized for their essential roles in fighting infections and regulating inflammation.

7 Jan 2025

New research reveals potential biomarkers for epilepsy diagnosis

New research led by UTHealth Houston scientists uncovered two genes associated with variants linked to epilepsy, which showed specific traits that make them promising diagnostic biomarkers.

6 Jan 2025

Newly identified genes may hold the key to understanding brain's response to PFAS

Per- and polyfluorinated alkyl substances (PFAS) earn their "forever chemical" moniker by persisting in water, soil and even the human brain.

6 Jan 2025

Study identifies how zinc deficiency can make drug-resistant bacteria vulnerable

Researchers at McMaster University have discovered a critical vulnerability in drug-resistant bacteria: zinc - or a lack thereof.

6 Jan 2025

Study unveils novel pathway triggering immune response to DNA damage

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

6 Jan 2025

Study reveals how smell and hearing interact in mouse brains

Imagine you're at a dinner party, but you can't smell the food cooking or hear the dinner bell. Sounds like a dream, right? What if it wasn't?

6 Jan 2025

RNA on leaf surfaces plays role in shaping plant microbiomes

Biologists at Indiana University Bloomington have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules.

3 Jan 2025

Oldest evidence of evolutionary arms race found in fossils

A new study led by researchers at the American Museum of Natural History presents the oldest known example in the fossil record of an evolutionary arms race.

3 Jan 2025

Breakthrough in protein homeostasis offers potential for preventing Alzheimer’s

Scientists have uncovered a powerful ally in the fight against neurodegenerative diseases: a nucleolar complex that plays a pivotal role in maintaining cellular health through protein homeostasis (proteostasis), by which cells maintain the balance and proper functioning of their proteins.

3 Jan 2025