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Haier Biomedical offers improved access to liquid nitrogen storage

Haier Biomedical has launched a new generation of liquid nitrogen containers offering easy and convenient access to stored samples.

From Haier Biomedical 13 Jun 2024

Release of Unity 2.0: Order, track, and manage your compound collection through one platform

eMolecules has launched a new updated platform that enables medicinal chemists or compound managers to order, track, and manage their compound collection and commercial sources through a more intuitive and flexible system: Unity.

From eMolecules 13 Jun 2024

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

In this interview, we speak with Melanie Leveridge, Vice President of Discovery Biology at AstraZeneca and Chair of the Board for ELRIG UK, to discuss her extensive career in the pharmaceutical industry, her role in fostering scientific innovation, and her vision for ELRIG's future.

From ELRIG (UK) Ltd. 13 Jun 2024

Deep learning revives ancient peptides to battle antibiotic resistance

Researchers used deep learning to resurrect antibiotic peptides from extinct organisms, offering new solutions for combating antibiotic resistance.

12 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

Germ cells drive sex-dependent lifespan differences in vertebrate animals

Women live longer than men. This isn't unique to humans, either; we see this trend in a wide range of other animals.

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer.

12 Jun 2024

Study identifies genetic predictors of X chromosome loss in aging women

Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Study reveals exploitation mechanism of virus-related nanoparticles for bacterial proliferation

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

11 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024

Breathing New Life into Diagnostics: Plasmion's SICRIT® Technology

Revolutionizing Non-Invasive Diagnostics with Plasmion’s SICRIT Breath Analysis.

From Plasmion 11 Jun 2024

Study unlocks the secrets of mammalian longevity through DNA methylation analysis

Researchers developed DNA methylation-based models predicting maximum lifespan, gestation, and sexual maturity across 348 mammalian species, revealing key epigenetic markers of longevity.

10 Jun 2024

Discovery could accelerate efforts to produce new antibiotics in the fight against antimicrobial resistance

A discovery made by scientists at King's College London could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.

10 Jun 2024

Genome sequencing identifies genetic disorders missed by exome analysis

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

10 Jun 2024

Transforming antibody drug discovery with Epitope Binning-seq

Monoclonal antibodies are crucial therapeutics due to their high specificity and binding affinity for epitopes (the precise sites where an antibody attaches itself to an antigen, triggering an immune response).

10 Jun 2024

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

10 Jun 2024