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Exercise temporarily improves muscle insulin resistance linked to genetic risk for type 2 diabetes

The study uncovers how acute exercise alleviates insulin resistance in TBC1D4 variant carriers, underscoring the need for personalized diabetes interventions.

4 Nov 2024

Rare neural crest stem cells identified as key drivers of cellular reprogramming

A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other researchers.

3 Nov 2024

Study identifies cellular and molecular roots of individual brain connectivity differences

Researchers link microscopic protein structures and cellular interactions to individual differences in brain connectivity, offering new insights into brain function and variability.

3 Nov 2024

Clues from the Mary Rose: Bone chemistry reveals age and handedness of Tudor sailors

Researchers used Raman spectroscopy to study bone chemistry in sailors from the Mary Rose, revealing aging patterns and potential handedness impacts on clavicles.

3 Nov 2024

New pathway discovery explains MRSA's high-level antibiotic resistance

Researchers have discovered a new cell division pathway in MRSA that enables high-level resistance to β-lactam antibiotics, marking a critical insight into the persistence of these 'superbugs'.

3 Nov 2024

New imaging method could transform gene expression research

They say a picture is worth a thousand words. A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024

Adolescents' genetic risks tied to psychotic symptoms

Researchers examine the relationships between neuropsychiatric and cognitive polygenic scores, attention-related phenotypes, and psychosis symptoms.

1 Nov 2024

Research reveals role of IGFBP3 in human lung development

Researchers of the University of Barcelona and the August Pi y Sunyer Biomedical Research Institute (IDIBAPS) have shown that the IGFBP3 protein plays a relevant role in human lung development.

1 Nov 2024

New technology streamlines drug discovery using single-molecule tracking

New drug discovery is a critical step for improving patients' lives. First, researchers must identify molecules in the body's cells that help drive disease, as these are potential targets for new drugs. The next step is to screen candidate drugs that can hit those targets.

1 Nov 2024

Mitochondrial genetics shed light on ALS Risk and protection

Using sequencing techniques, researchers associated 51 mutations in mitochondrial DNA with amyotrophic lateral sclerosis (ALS), an incurable degenerative neurological disorder that leads to muscle atrophy and paralysis.

31 Oct 2024

Mapping tumor microenvironments: Uncovering spatial subclones for improved cancer treatment

Researchers investigate the spatial organization of cancer cells and the tumor microenvironment.

31 Oct 2024

Deep learning techniques transform protein structure prediction

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction.

30 Oct 2024

Understanding protein transport mechanisms could enhance crop yields

Botanists have come to understand the channels and transporters involved in the uptake and transport of nutrients, yet how are they positioned where they need to be?

30 Oct 2024

Researchers identify genetic markers linked to neuropathic pain

European researchers have mapped the most comprehensive phenotyping of neuropathic pain and identified genetic markers associated with this serious condition.

30 Oct 2024

Fabric Genomics partners with Intermountain Children’s Health to enhance precision diagnosis of infants and children using whole genome sequencing from Broad Clinical Labs

Fabric Genomics, the leader in artificial intelligence (AI)-powered next generation sequencing interpretation, is announcing a new partnership with Intermountain Children’s Health to analyze the whole genomes of children sequenced by the Broad Clinical Labs to help speed diagnosis of kids who may have genetic diseases.

From Fabric Genomics 30 Oct 2024

descendantsDNA, Inc. engages Broad Clinical Labs and Fabric Genomics for genomic services to support human longevity

descendantsDNA, Inc. is pleased to announce a new agreement with Broad Clinical Labs (BCL) to advance human longevity through cutting-edge genomics.

From Fabric Genomics 30 Oct 2024

Drug repurposing offers hope for SYNGAP1 patients

The SynGAP Research Fund 501(c)(3) has awarded a pair of grants to Dr. Clement Chow, a geneticist and Associate Professor in the Department of Human Genetics at the University of Utah. These grants are crucial steps in advancing therapeutic development for SYNGAP1-Related Disorders (SRD).

30 Oct 2024

New device enables real-time monitoring of stem cell growth

Unlike most cells in the human body, stem cells have the unique ability to divide indefinitely. This unique property makes them especially appealing to scientists exploring ways to extend human lifespans or develop new methods for repairing damaged tissues.

30 Oct 2024

Study questions causal link between cannabis and brain changes

Lifetime cannabis use is associated with several changes in brain structure and function in later life, suggests an observational study, but these associations may not be causal, finds a genetic analysis of the same data, published in the open access journal BMJ Mental Health.

30 Oct 2024

Researchers identify genetic markers for cardiovascular disease

A team of researchers from Girona Biomedical Research Institute Dr. Josep Trueta (IDIBGI), Bellvitge Biomedical Research Institute (IDIBELL), IRB Barcelona, Institut Català d'Oncologia (ICO), Germans Trias i Pujol Research Institute (IGTP) has worked together to identify possible genes associated with certain metabolites - molecules involved in the body's biochemical processes - and cardiovascular risk.

30 Oct 2024