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New mathematical method to map cell regulatory networks

Faster results. Lower costs. Fewer cells. A new mathematical method developed by researchers at Cincinnati Children's and New York University may soon make it much easier to conduct more of the complex data analysis needed to drive advances in the exploding field of personalized medicine.

6 Mar 2019

Researchers discover facile method for introduction of fluorine atoms into organic molecules

The vast majority of pharmaceuticals employed in the treatment of human diseases are of an organic nature, meaning that the active component is a molecule (or a combination of several molecules) that is constituted of carbon and hydrogen atoms.

6 Mar 2019

Liver tissue model can help investigate the effects of RNA interference

Novel therapies based on a process known as RNA interference hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

6 Mar 2019

New approach to creating 'theranostics' for targeting specific tumors, diseases

A City of Hope scientist and his colleagues have developed a user-friendly approach to creating "theranostics" - therapy combined with diagnostics - that target specific tumors and diseases.

6 Mar 2019

Study sheds new light on early development of embryos

By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilized egg to living being. The study is published in the scientific journal Cell Reports.

5 Mar 2019

Lonza expands portfolio with addition of new 'Verified for Spheroids Human Hepatocytes'

Lonza has further expanded its hepatocytes portfolio characterization with the addition of Verified for Spheroids Human Hepatocytes, which are pre-screened for their ability to promote rapid spheroid formation in cell culture.

From Lonza 5 Mar 2019

Oxford Genetics successfully negotiates six licensing deals

Mercia Technologies PLC, the national investment group focused on the identification, creation, funding and scaling of innovative technology businesses with high growth potential from the UK regions, today announces that its portfolio company, Oxford Genetics Limited, has successfully negotiated six licensing deals for its scalable gene therapy manufacturing technologies in the last twelve months.

From OXGENE 5 Mar 2019

Evolutionary expansion of the human brain is under strong genetic control

An analysis of brain scans from more than 600 children and adolescents reveals correlations between size of brain regions unique to humans and intelligence test scores.

From Society for Neuroscience 5 Mar 2019

Isolating Bacterial Pathogen DNA from Food Samples

Isolating bacterial pathogen DNA is important and often seen as QA ensure that the food manufactured or the ingredients used do not contain food-borne bacteria.

From Promega Corporation 5 Mar 2019

Study unravels microscopic mysteries in the brains of C. elegans

It's the small pieces that make the big picture, and in this case, the pieces can't be seen by the naked eye. New research at the Okinawa Institute of Science and Technology Graduate Universit used microscopy techniques to piece together the brain of the millimeter-long Caenorhabditis elegans, revealing that their neurons fire action potentials - a spike in voltage due to neurons sending sensory information in the cell membrane.

5 Mar 2019

Genetic breakthrough could pave way for a new drug to prevent, heal painful mouth ulcers

A large breakthrough has been made in the genetic understanding of mouth ulcers which could provide potential for a new drug to prevent or heal the painful lesions.

5 Mar 2019

Genomics could guide treatment for pancreatic cancer patients

Pancreatic cancer is a grim diagnosis, with a five-year survival rate of less than 9 percent. To improve those odds, researchers at UPMC and the University of Pittsburgh School of Medicine sought genetic signatures in the largest study of its kind that could be used to better match drugs to patients and for early detection.

5 Mar 2019