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Expanding the toolbox for drug design: New enzymes for tailoring molecules

Simon Schröder has worked out how enzymes can be used to more easily form the desired bond between two nitrogen atoms.

8 Dec 2023

Scientists unveil 3D structure of key immune system component

An international team of researchers from LMU and the Helmholtz Centre for Infection Research has visualized the structure of the so-called ASC speck.

8 Dec 2023

Genome-wide study shows strong negative correlation between reproduction and lifespan

A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain aging and senescence.

8 Dec 2023

T cells can recognize and fight the "Pirola" variant, new study suggests

In August, researchers detected a new SARS-CoV-2 "variant of concern" in patients in Israel and Denmark.

8 Dec 2023

New insights into the structures formed during antibody aggregation through 3D domain swapping

Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising candidates for future drug development.

8 Dec 2023

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Study presents a genome-wide map, "Gnocchi," constructed from 76,156 human genomes, revealing that non-coding regions rich in regulatory elements are crucial in understanding human traits and diseases.

7 Dec 2023

Researchers identify 25 new genetic markers linked to peptic ulcers

Researchers studied stomach and duodenal ulcers in a large research project comparing Japanese and European populations.

7 Dec 2023

Study finds link between epimutations in BRCA1 gene and triple-negative breast cancer risk

Research reveals that around 20 per cent of all cases of the most severe form of breast cancer may arise from the small group of normal tissue cells carrying an epimutation of a specific gene.

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Researchers created Drosophila models using multi-omics profiles to elucidate the biological mechanisms and effects of everyday low-intensity blue light exposure (BLE).

7 Dec 2023

Ashwagandha extracts show promise in reducing stress hormones, study suggests

A systematic review reveals that Withania somnifera (Ashwagandha) extracts can effectively reduce cortisol levels in the short term, offering a natural alternative for stress management, though long-term effects remain unexplored.

6 Dec 2023

Design modifications offer promise for safer and more effective mRNA therapeutics

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body.

6 Dec 2023

MedUni Vienna scientists discover new pain medication with fewer side effects

People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects.

6 Dec 2023

Camena Bioscience appoints Dr. Nicola Thompson as Chair of the Board

Camena Bioscience, a synthetic biology company providing genes to the pharmaceutical and biotechnology industries, today announced it has appointed Dr Nicola Thompson as Chair of its Board of Directors.

From Camena Bioscience 6 Dec 2023

Exploring the genetic links: Alcohol, smoking, coffee intake, and arthritis risk

The genetic relationship between alcohol consumption, smoking, coffee intake, and the risk of arthritis.

6 Dec 2023

Pioneering Visions: Michael Stryker's Contributions to Understanding the Visual Cortex

In this interview conducted at the Society for Neuroscience's Neuroscience 2023, we explore the fascinating world of neuroscience with Professor Michael Stryker, a leading expert with over four decades of groundbreaking research.

6 Dec 2023

Revolutionary self-folding nanoscale MRI agent sharpens cancer imaging

Study introduces a novel self-folding nanoscale contrast agent for MRI, enhancing tumor visualization with lower gadolinium loads and reduced risk of adverse effects.

5 Dec 2023

Targeting Alzheimer's with cell-specific genetics

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

5 Dec 2023

Fruit fly study highlights potential risks of cumulative blue light exposure

In a study on fruit flies, daily low-intensity blue light exposure (BLE), similar to that experienced daily by billions of humans in the form of LED lighting and device screens, changed flies at the sub-cellular level, affecting processes related to aging and circadian rhythms.

5 Dec 2023

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms.

5 Dec 2023

Life Science News

Expanding the toolbox for drug design: New enzymes for tailoring molecules

Scientists unveil 3D structure of key immune system component

Genome-wide study shows strong negative correlation between reproduction and lifespan

T cells can recognize and fight the "Pirola" variant, new study suggests

New insights into the structures formed during antibody aggregation through 3D domain swapping

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Researchers identify 25 new genetic markers linked to peptic ulcers

Study finds link between epimutations in BRCA1 gene and triple-negative breast cancer risk

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Ashwagandha extracts show promise in reducing stress hormones, study suggests

Design modifications offer promise for safer and more effective mRNA therapeutics

MedUni Vienna scientists discover new pain medication with fewer side effects

Camena Bioscience appoints Dr. Nicola Thompson as Chair of the Board

Exploring the genetic links: Alcohol, smoking, coffee intake, and arthritis risk

Pioneering Visions: Michael Stryker's Contributions to Understanding the Visual Cortex

Revolutionary self-folding nanoscale MRI agent sharpens cancer imaging

Targeting Alzheimer's with cell-specific genetics

Fruit fly study highlights potential risks of cumulative blue light exposure

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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