Nidhi Saha

A cigarette smoke compound affects cartilage homeostasis

Cigarette smoke has been shown to deleteriously affect human health. For example, degenerative disc diseases are increasingly linked to cigarette smoking.

mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2

A new study examined the protective effect of the mRNA booster vaccine against the SARS-CoV-2 Omicron variant in 21-month-old mice.

The long-term impact of prior SARS-CoV-2 infection on immune responses after COVID-19 vaccination

The study aimed to determine the impact of prior infection from SARS-CoV-2 infection on immune responses after COVID-19 vaccination in the long term.

Species differences in somatic mutations shed light on aging

A recent study published in the journal Nature aimed to elucidate, through a comparative analysis, the diversity in mutagenesis across different species, and the long-established hypothesis regarding evolution in the rates of somatic mutation, as well as their role in cancer and aging.

RNA splicing abnormalities in COVID-19 patients

This study entailed the integration of multiple-omics datasets to examine the dysregulation in the host splicing mechanism and alteration in protein isoforms among COVID-19 patients.

Genomic characterization of the circulating SARS-CoV-2 lineages in Papua New Guinea

A recent study characterized the SARS-CoV-2 lineages circulating in Papua New Guinea during the second wave of COVID-19.

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

A new study investigated whether APOBEC proteins can directly edit the RNA sequence of SARS-CoV-2 to generate C-to-U mutations.

Novel transdermal vaccine delivery for COVID-19 and cancer

Researchers assess the efficacy of a fluorocarbon modified chitosan system for the development of SARS-CoV-2 vaccines and tumor immunotherapy.

COVID-19 increases risk of bleeding, DVT, and pulmonary embolism

Study investigates changing patterns of SARS-CoV-2 infection through Delta and Omicron waves

A new study examined whether SARS-CoV-2 infections in England varied by vaccination status, in cases with a previous COVID-19 positive test report individual, and by neighborhood socioeconomic deprivation, across the Delta and Omicron waves.