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Scientists isolate genes that made 1918 flu lethal

By mixing and matching a contemporary flu virus with the "Spanish flu" - a virus that killed between 20 and 50 million people 90 years ago in history's most devastating outbreak of infectious disease - researchers have identified a set of three genes that helped underpin the extraordinary virulence of the 1918 virus.

30 Dec 2008

Salix Pharmaceuticals receives FDA response for Balsalazide tablet

Salix Pharmaceuticals, Ltd. has announced that the Company has received a complete response letter from the U.S. Food and Drug Administration (FDA) for its New Drug Application (NDA) for balsalazide tablet studied as a treatment of mild-to-moderate active ulcerative colitis in patients 18 years and older.

30 Dec 2008

Pegloticase BLA filing accepted for priority review by FDA

Savient Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has accepted for review the Company's Biologics License Application (BLA) for pegloticase, a novel biological drug for treatment-failure gout (TFG) patients.

30 Dec 2008

Human hair waste may be a viable option as fertilizer for edible crops

Agricultural crop production relies on composted waste materials and byproducts, such as animal manure, municipal solid waste composts, and sewage sludge, as a necessary nutrient source.

30 Dec 2008

New study examines effects of chlorine gas disaster in South Carolina

A new study examining the aftereffects of a chlorine gas disaster in a South Carolina town gives larger metropolitan areas important insight into what to expect and how to prepare emergency response systems for an accidental or terrorist release of the potentially deadly gas.

30 Dec 2008

Moderate drinking lowers risk of Alzheimer's and cognitive decline

Moderate drinkers often have lower risks of Alzheimer's disease and other cognitive loss, according to researchers who reviewed 44 studies.

30 Dec 2008

Obesity has minimal impact on ovarian cancer survival

Obesity affects health in several ways, but new research shows obesity can have minimal impact on ovarian cancer survival.

30 Dec 2008

May hepatic granulomas be part of the histological spectrum of chronic hepatitis C?

While older large series of patients with hepatic granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic granulomas, recent works have noted some patients with chronic hepatic C and hepatic granulomas and no other obvious associations.

30 Dec 2008

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org).

30 Dec 2008

All VX nerve agent munitions destroyed in U.S.

The U.S. Army Chemical Materials Agency (CMA) marked the destruction of all VX nerve agent munitions at its destruction sites on Wednesday, Dec. 24, 2008.

30 Dec 2008

How to enhance non-thermal effects of ultrasound

In recent years HIFU has been widely used for the treatment of solid tumors, such as liver tumor, bone tumor, and breast cancer.

30 Dec 2008

Long-term gene therapy used to reverse heart damage in heart failure

Long-term gene therapy resulted in improved cardiac function and reversed deterioration of the heart in rats with heart failure, according to a recent study conducted by researchers at Thomas Jefferson University's Center for Translational Medicine.

30 Dec 2008

Antifungal medication could provide asthma relief for 150,000 UK sufferers

Up to 150,000 people suffering from severe asthma in the UK could benefit from taking antifungal medication already available from pharmacists, new research has found.

From The University of Manchester 30 Dec 2008

Contact with plants shown to directly benefit patient's health

Contact with nature has long been suspected to increase positive feelings, reduce stress, and provide distraction from the pain associated with recovery from surgery.

30 Dec 2008

FDA issues complete response letter to Ipsen for Dysport BLA

Ipsen has announced that the US Food and Drug Administration (FDA) issued a Complete Response Letter for its Biologics License Application (BLA) for its Botulinum toxin Type A, Dysport.

30 Dec 2008

Family rejection of lesbian, gay and bisexual children linked to poor health in early childhood

For the first time, researchers have established a clear link between family rejection of lesbian, gay and bisexual (LGB) adolescents and negative health outcomes in early adulthood.

30 Dec 2008

Family members of critically ill patients want to discuss loved ones' uncertain prognoses

Critically ill patients frequently have uncertain prognoses, but their families overwhelmingly wish that physicians would address prognostic uncertainty candidly, according to a new study out of the University of San Francisco Medical Center.

30 Dec 2008

Cystic fibrosis patients' self-assessment of health can predict prognosis

Adult Cystic Fibrosis patients can provide important information that helps to predict their prognosis, according to research that asked 223 adult CF patients to assess their own health and well-being.

30 Dec 2008

Diet high in inorganic phosphates increases risk of lung cancer

New research in an animal model suggests that a diet high in inorganic phosphates, which are found in a variety of processed foods including meats, cheeses, beverages, and bakery products, might speed growth of lung cancer tumors and may even contribute to the development of those tumors in individuals predisposed to the disease.

30 Dec 2008

Chronic gastrointestinal symptoms in Korean population

Chronic gastrointestinal symptoms are highly prevalent in different geographic populations and cause various gastrointestinal symptoms that greatly inconvenience the lives of those affected.

30 Dec 2008