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New view of what causes greatest genetic variability among individuals

A study by Yale researchers offers a new view of what causes the greatest genetic variability among individuals - suggesting that it is due less to single point mutations than to the presence of structural changes that cause extended segments of the human genome to be missing, rearranged, or present in extra copies.

27 Sep 2007

People with a strong fear of crime twice as likely to show symptoms of depression

The research, based on data taken from the Whitehall II study, also shows that fear of crime is associated with decreased physical functioning and lower quality of life. The findings are published today in the American Journal of Public Health.

27 Sep 2007

High school footballers wearing special helmets to monitor brain injuries

As they root for the home team from the bleachers this fall, high school gridiron fans in the small Illinois town of Tolono don't necessarily see anything out of the ordinary down on the field.

27 Sep 2007

New guidelines for cardiac testing and treatments

People with heart disease should take special precautions before undergoing any kind of surgery, even noncardiac surgery, to reduce their risk of a cardiac event, according to new joint guidelines from the American College of Cardiology and the American Heart Association.

27 Sep 2007

Genetic sequence of Giardia complete

Giardia lamblia, one of the most common human parasites in the United States, causes more than 20,000 intestinal infections a year, often through contact with contaminated drinking or swimming water.

27 Sep 2007

Variations in two genes linked to suicidal thinking

Specific variations in two genes are linked to suicidal thinking that sometimes occurs in people taking the most commonly prescribed class of antidepressants, according to a large study led by scientists at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

27 Sep 2007

Genetic test announced for suicidal ideation in patients using antidepressant drugs

NeuroMark, a Boulder, Colorado company, announced today the immediate availability of a genetic test to identify people at risk of suicidal ideation - thoughts of committing suicide - when prescribed an antidepressant drug.

27 Sep 2007

Many patients with diabetes say burden of care rivals complications of disease

Many patients with diabetes say that the inconvenience and discomfort of constant therapeutic vigilance, particularly multiple daily insulin injections, has as much impact on their quality of life as the burden of intermediate complications, researchers from the University of Chicago report in the October 2007 issue of Diabetes Care.

27 Sep 2007

Experimental drug pertuzumab boosts survival in recurrent ovarian cancer

New clinical data showed an experimental drug called pertuzumab prolonged the survival time for women with recurrent ovarian cancer, a University of Alabama at Birmingham doctor said recently.

27 Sep 2007

Over use of multivitamins may raise prostate cancer risk

About a third of American adults take some type of multivitamin on a regular basis.

27 Sep 2007

Expertise modulates the perception of pain in others

Physicians apparently learn to “shut off” the portion of their brain that helps them appreciate the pain their patients experience while treating them and instead activate a portion of the brain connected with controlling emotions, according to new research using brain scans at the University of Chicago.

27 Sep 2007

DNA damage response confers a barrier for viral tumorigenesis

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma (KS).

27 Sep 2007

Dietary fatty acids may help prevent diabetes

Omega-3 fatty acids have long been touted for their heart-healthy and brain-boosting benefits. Consider cod liver oil, fortified infant formula and enriched eggs.

27 Sep 2007

Clinical trials for diabetes drugs should measure outcomes important to patients

Most clinical trials for new diabetes drugs do not consider the impact medication will have on a patient's quality of life or other outcomes that are important to patients, such as the risk of developing complications associated with diabetes, according to a Mayo Clinic commentary in the current issue of The Lancet.

27 Sep 2007

Clinical Trials Directive likely to turn Europe into the poor relation of clinical academic medicine

The Clinical Trials Directive, which came into force in May 2004 in order to create a harmonised framework for clinical drug research across Europe, is still hampering such research, according to new findings presented at the European Cancer Conference (ECCO 14).

27 Sep 2007

Climate change may increase heat-related deaths by 2050

While some uncertainty does exist in climate projections and future health vulnerability, overall increases in heat-related premature mortality are likely by the 2050s, according to a recent study by Columbia University's Mailman School of Public Health and soon to be published in the November 2007 issue of the American Journal of Public Health.

27 Sep 2007

Chemotherapy drug gemcitabine delays progression of operable pancreatic cancer

Barcelona, Spain: Giving pancreatic cancer patients the chemotherapy drug gemcitabine after surgery delays progression of the disease by about six months, according to new research by Japanese scientists.

27 Sep 2007

CDC awards $35 million to increase HIV testing opportunities

The Centers for Disease Control and Prevention has awarded $35 million in funding to state and local health departments to increase HIV testing opportunities among populations disproportionately affected by HIV, primarily African Americans.

27 Sep 2007

Biodel issued U.S. patent for VIAject and VIAtab

Biodel Inc. has announced the receipt of a notice of issuance from the United States Patent and Trademark Office (USPTO) for the Company's patent encompassing VIAject(TM) and VIAtab(TM), Biodel's two product candidates in clinical trials.

27 Sep 2007

Tumor cell receptor provides new therapeutic target

Working with a line of highly metastatic head and neck cancer cells, a research team at the Winship Cancer Institute and Emory University School of Medicine has found that a specific cell surface receptor present at very low levels in non-metastatic head and neck cancer cells.

27 Sep 2007