Rubella no threat in U.S.

Mar 21 2005

Dr. Julie Gerberding, director, Centers for Disease Control and Prevention ,speaking at the National Immunization Conference Washington, DC, says the rubella virus, a major cause of serious birth defects such as deafness and blindness, also known as congenital rubella syndrome (CRS) is no longer considered to be a major public health threat in the United States.

A major public health milestone has been achieved with the elimination of rubella and this is a tremendous step in protecting the health and well being of pregnant women and infants, said Dr. Gerberding.

The availability of a safe and effective vaccine and successful immunization programs across the country has meant that a disease that once seriously harmed tens of thousands of infants is no longer a major health threat, but vigilance must be maintained to avoid a resurgence of the disease.

The majority of the nation’s children under age two are vaccinated against measles, mumps and rubella, and almost all of the nation’s children are vaccinated against rubella by the time they enter school. “The importance of continuing vaccination cannot be emphasized enough, “said Dr. Steve Cochi, Acting Director, CDC’s National Immunization Program. “Cases of rubella continue to be brought into the country by worldwide travelers and because of bordering countries where the disease is active.”

A rubella epidemic in the United States in the year1964 to 65 caused an estimated 12.5 million cases of rubella and 20,000 cases of congenital rubella syndrome (CRS) which led to more than 11,600 babies born deaf, 11,250 fetal deaths, 2,100 neonatal deaths, 3,580 babies born blind and 1,800 babies born mentally retarded.

Recording of rubella incidences began in 1966, and the largest number of rubella cases reported was in 1969 with 57,686 cases. Since the vaccine was licensed in 1969 and the implementation of a rubella vaccination program to prevent infection during pregnancy, rubella incidence fell, and by 1983, fewer than 1,000 cases were reported each year. A resurgence in rubella and measles cases was evident during the measles epidemic from 1989-1991 and in 1989, CDC established a rubella elimination goal and despite the resurgence, reported rubella cases in the 1990s declined to an all-time low. From 1990 through 1999, only 117 cases of CRS were reported, 66 of these babies were born in 1990 and 1991. In 2001, for the first time in history, less than 100 cases were reported in the United States. In 2003, there were only eight rubella cases and one CRS case reported in the United States. In 2004, there were only nine rubella cases reported in the United States.

The United States has worked closely with the Pan American Health Organization (PAHO) and Mexico to improve rubella control in the Americas since the 90's and these efforts have resulted in dramatic reductions of rubella in many nations of the Americas. In September 2003, ministers of health of all countries in the Americas resolved to eliminate rubella and CRS by 2010.

An independent panel including internationally recognized immunization experts from academia, the Council for State and Territorial Epidemiologists (CSTE), the Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics (AAP), the American Academy of Family Physicians (AAFP), the Pan American Health Organization (PAHO), Mexico and the CDC concluded late last year that rubella is no longer endemic in the United States. Rubella is prevented through vaccination and is recommended for all children, adolescents and adults without documented evidence of immunity.

It is especially important that all women of child-bearing age are given immunity to rubella before they become pregnant. It is recommended that rubella vaccine be given as MMR vaccine (protecting against measles, mumps and rubella). The first dose of MMR should be given on or after the first birthday; the recommended range is from 12-15 months. The second dose is usually given when the child is 4-6 years old, or before he or she enters kindergarten or first grade. Maintaining high coverage and rubella population immunity in the United States.