Jan 7 2010
The
CFIDS Association of America issued the following statement in
response to a study published in today’s edition of PLoS
One that failed to detect the XMRV virus in banked samples drawn
from 186 CFS patients in the United Kingdom. A study published Oct. 8,
2009 in Science
reported that 68 of 101 CFS patients from clinics in the U.S. tested
positive for XMRV.
“Without a standardized method of detecting XMRV,
millions of dollars might be wasted on independent attempts to determine
the prevalence of XMRV in different populations.”
“The CFIDS Association of America reviewed the study published in
today’s edition of PLoS One. We are concerned about many elements
of this study including differences between the patients selected by the
two groups, different processes used to collect and test the blood
samples, and the rapid nature of the new publication, as evidenced by
the three days that separated the dates of submission and acceptance,”
stated K. Kimberly McCleary, president and CEO of the CFIDS Association
of America. “We urge the media and the research and patient communities
to view these findings in the context of evolving understanding and to
insist upon more rigorous and standardized replication studies before
drawing conclusions about the role of XMRV in the pathophysiology of
CFS.”
CFIDS Association scientific director Suzanne
D. Vernon, PhD, made the following assessment: “The new report from
the U.K. should not be considered a valid attempt to replicate the
findings described by Lombardi, et al., in the Science article.
This paper heavily underscores the need for expedient, yet robust,
XMRV-focused research to build upon the results reported this past fall,
studies like the one being conducted by the Department of Health and
Human Services Blood XMRV Scientific Research Working Group.” Vernon
holds her doctorate in virology from the University of Wisconsin and had
17 years experience in public health research on infectious diseases
before joining the Association’s staff in 2007 to lead its research
program. She added, “Without a standardized method of detecting XMRV,
millions of dollars might be wasted on independent attempts to determine
the prevalence of XMRV in different populations.”
“Every person whose life has been impacted by CFS wants urgently to
identify the cause of and a cure for this devastating condition that
affects millions of people worldwide. While time is of the essence, we
must insist upon rigorously conducted and reviewed science that provides
absolute validation, definitive answers and unbridled hope,” said
McCleary.
http://www.cfids.org/