ConvaTec, a world-leading developer and marketer of innovative medical technologies for community and hospital care, today announced new in vitro study results in which a Hydrofiber® dressing containing ionic silver was observed to conform more closely to a porcine tissue surface in a shallow wound model than did certain silver-containing foam dressings following hydration. In the in vitro study the Hydrofiber® dressing containing ionic silver killed more bacteria (Pseudomonas aeruginosa and Staphylococcus aureus) beneath the dressing than any of the tested silver-containing foam dressings. In addition, the Hydrofiber® dressing containing ionic silver was observed to not allow the spread of bacteria beyond the edge of the simulated wound. These data were presented at the 23rd Annual Symposium on Advanced Wound Care and Wound Healing Society (SAWC/WHS) in Orlando, Florida.
Chronic wounds are often made up of many types of bacteria from external sources such as the surrounding skin, gut and mouth. A wound that will not heal is an excellent environment for bacteria to colonize. Colonizing bacteria can often lead to difficult-to-treat infections. It is important that a wound dressing conforms well to the wound's unique topography to ensure that an antimicrobial agent comes into the most contact with the threatening bacteria.
In the in vitro study, models were utilized that enabled both visualization of the conformability of silver-containing dressings with a simulated wound tissue and measurement of the antimicrobial activity of the dressings in a simulated shallow wound microbial model. The percentage of growth for each bacterium was measured for Hydrofiber® dressing containing ionic silver and three silver-containing foam dressings (Foam A-C). Mean results of three replicated tests, measured by growth beneath the dressing, were as follows: the Hydrofiber® dressing containing ionic silver had 0.4% growth when inoculated with S. sureus and 9.0% with P. aeruginosa; Foam A had 25.7% growth when inoculated with S. aureus and 100% with P. aeruginosa; Foam B had 16.7% growth when inoculated with S. aureus and 97.8% with P. aeruginosa; and Foam C had 24.6% growth when inoculated with S. aureus and 95.8% wit P. aeruginosa.
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