New research from the laboratory of Dr. Elizabeth Leadbetter at the Trudeau Institute may lead to a whole new class of vaccines. Dr. Leadbetter's lab has discovered new properties of a potential vaccine adjuvant that suggest it could be useful for enhancing protection against a number of different infections. This new data will be published in the January 2012 issue of the journal Nature Immunology (Vol. 13, pp. 44-50). The paper, "iNKT cells direct B cell responses to cognate lipid antigen in an interleukin 21-dependent manner," is now available through Advance Online Publication (AOP) on Nature Immunology's website at http://www.nature.com/ni/journal/vaop/ncurrent/full/ni.2172.html.