Okay I have to confess this from the get-go that this article title hits a pet peeve of mine which is media over statement about the dimensions of a piece of novel science. It is a serious overreach to say that this fellow has "discovered the cause of progression of Alzheimer's disease". That's misleading, and any serious scientist would jump all over that. What he's discovered is a heretofore underappreciated dimension of protein aggregation. That is a far cry from discovering some totally unknown factor that's involved in progression. Additionally protein aggregation or what is termed proteinopathy is not the same thing as a comprehensive understanding of what's driving neurodegeneration in AD which is surely a hugely multifactorial. Hype and this kind of over each and overstatement in a sense are the opposite of good science reporting.