I have a pituitary macroadenoma on my posterior pituitary to the pars intermedium and on some portion of anterior. This is not the most common area to have one from what my husband has read. There is a real lack of research on how this can affect a woman's progesterone, FSH. I have horrible headaches, melasma and borderline low cortisol, but none of the doctors in the South seem to care or have a lot of current research insight. The state of our medical care in the USA is horrible. The South is like a 3rd world country for care with a few exceptions. Doctors spend 5 minutes with you. Please research this more and don't just dismiss that it is a common thing. A large lesion is not common, it effects my life, my moods, my cortisol and many other things. More needs to be done to research this.