Biodegradable long-acting injectable implants prepared by hot melt extrusion

Injectable implants have distinct advantages for certain applications; for example, their efficacy over a long period of time can increase patient compliance, and the drug substance is applied in a non-systemic manner. Development and manufacturing of these implants often involves polymers as a matrix which makes twin-screw extrusion a perfect technology for their development. Nevertheless, it is a comparatively new technology and much can still be learned about the applicability and benefits of twin-screw extrusion. This seminar aims to give an introduction as well as real-life examples of what to look out for when entering this field of pharmaceutical manufacturing.

Speakers

Key learning objectives

• Learn how you can prepare long lasting implants using Hot Melt Extrusion
• Gain an overview and applications for injectable implants
• What to consider when choosing polymeric matrices for drug delivery systems

Who should attend

• Formulation scientists and engineers in the pharmaceutical industry
• Academia who want to learn more about the possibilities to utilize HME for implant development and manufacturing

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