Posted in | Pharmaceuticals and Drug Discovery

Introduction to hot melt extrusion for pharmaceutical applications

From Thermo Fisher Scientific – Materials Characterization Feb 14 2024

90% of new molecules and roughly 40% of the top solid oral drugs marketed in the U.S. and Europe have generally low solubility. Hot-melt extrusion (HME) can help to overcome these challenges as the technique can enhance the solubility and bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Transition from inefficient batch processing to continuous manufacturing, and produce novel delivery systems such as injectable implants and oral dispersible films (ODFs).

About the presenter

Dr. Margarethe Richter is a Pharma Application Specialist at Thermo Fisher Scientific, where she develops new applications related to pharmaceutical hot melt extrusion and twin-screw granulation. She earned her PhD degree (Dr.-Ing.) researching at the German Aerospace Center (DLR) on thermodynamic and reaction kinetics. Dr. Richter is a chemical engineer by training and graduated from the Karlsruhe Institute of Technology (KIT).

Other Webinars from Thermo Fisher Scientific – Materials Characterization

Biodegradable long-acting injectable implants prepared by hot melt extrusion

Biodegradable long-acting injectable implants prepared by hot melt extrusion

Medical Webinars by Subject Matter

Watch the
Webinar

Hi, I'm Azthena, you can trust me to find commercial scientific answers from News-Medical.net.

To start a conversation, please log into your AZoProfile account first, or create a new account.

Registered members can chat with Azthena, request quotations, download pdf's, brochures and subscribe to our related newsletter content.

A few things you need to know before we start. Please read and accept to continue.

Use of “Azthena” is subject to the terms and conditions of use as set out by OpenAI.
Content provided on any AZoNetwork sites are subject to the site Terms & Conditions and Privacy Policy.
Large Language Models can make mistakes. Consider checking important information.

I understand, and agree to receive occasional emails about Azthena such as usage tips and new feature announcements.

Please check the box above to proceed.

Great. Ask your question.

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.