Nicola Zamboni handpicks technologies for the PHRT Clinical Metabolomics Analysis Center with the potential to enhance clinical insights and decision-making, accelerating the voyage toward personalized medicine.
Streamlining metabolomic and lipidomic analyses to enable personalized therapies
The sheer amount of data gained via MS metabolomics and lipidomics analyses greatly contributes to our knowledge of biological systems, disease mechanisms, and possible therapeutic targets.
Applying novel technologies to these efforts enables researchers and clinicians to work more effectively and obtain insights faster. Sophisticated instrumentation empowers abilities and provides higher sensitivity, durability, and speed, enabling more precise and detailed analyses of complicated biological samples.
With these tools, scientists can distinguish and quantify a wider spectrum of metabolites and lipids, resulting in a better understanding of biochemical pathways and disease processes.
Faster, deeper, simpler: a new era in metabolomics and lipidomics profiling
Dr. Nicola Zamboni investigates the abilities of the ZenoTOF 7600 system in his labs. As an extremely flexible system, it has all the properties Dr. Zamboni’s team needs: speed, sensitivity, precision, dynamic range, a high quantity of MS2 information, and comprehensive structural elucidation, all in a singular, complete package.
This sophisticated technology meets their expectations and empowers them to conduct their day-to-day tasks with both confidence and ease.
Dr. Zamboni showcases the system’s superb performance by applying it to lipidomics analyses—large-scale studies frequently requiring speed. With no start-up time, the system demonstrates flexibility and accuracy, presenting its ability to grasp complicated lipidomic samples without alteration.
Using EAD fragmentation, vast quantities of data can be acquired quickly, enabling more profound insights throughout a routine analysis. This timesaving method delivers rich information that aids in uncovering complicated biological processes.
The ZenoTOF 7600 system is entertaining and valuable for Nicola Zamboni and his team. It exceeds expectations and enables them to rapidly obtain useful data.
Key takeaways
- The ZenoTOF 7600 system merges top speed, robustness, sensitivity, dynamic range, and deep collection of rich MS2 data on a chromatographic timescale
- EAD spectra have large quantities of data. Lipid EAD spectra are predictable with naïve fragments
- We can effectively identify, calculate, and structurally explain over 1000 lipids in 2-min gradients in real samples
Image Credit: SCIEX
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About SCIEX
SCIEX mission is to deliver solutions for the precision detection and quantitation of molecules, empowering their customers to protect and advance the wellness and safety of all.
SCIEX has led the field of mass spectrometry for 50 years. From the moment we launched the first ever commercially successful triple quad in 1981, they have developed groundbreaking technologies and solutions that influence life-changing research and outcomes.
Today, as part of the Danaher family of global life science and technology innovators, they continue to pioneer robust solutions in mass spectrometry and capillary electrophoresis. But they don’t just develop products. It is what they do together with their customers that sets them apart. That’s why thousands of life science experts around the world choose SCIEX to get the answers they can trust to better inform critical decisions. Decisions that positively impact lives.
They proudly stand behind our tagline: The Power of Precision.
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