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Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

The findings from this study suggest that HPNs may inhibit viral replication and budding.

27 Sep 2021

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Despite the advent of numerous vaccines and the discovery of passive monoclonal antibodies for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), there remains an urgent need for definitive therapies for coronavirus disease-2019 (COVID-19) patients.

27 Sep 2021

Further evidence of safety and efficacy of mRNA-1273 vaccine in preventing symptomatic COVID-19 and SARS-CoV-2 infection

A recent study supports the efficacy of the mRNA-1273 vaccine in preventing COVID-19 illness and disease severity.

24 Sep 2021

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

A new study presents initial results from a randomized, placebo-controlled phase 1/2 trial in Thailand.

24 Sep 2021

Human milk antibodies elicited by vaccination show reduced activity against SARS-CoV-2 VoCs

In a study recently published on the medRxiv* preprint server, scientists from Singapore have assessed the levels of IgA-specific anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the breast milk of women recently immunized with the second dose of an mRNA-based coronavirus disease 2019 (COVID-19) vaccine.

24 Sep 2021

Effect of prior SARS-CoV-2 infection on post-vaccination SARS-CoV-2 spike IgG antibodies

Natural infection or vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confer considerable protection against reinfection and reduce the risk of severe Coronavirus disease 2019 (COVID-19) outcomes.

24 Sep 2021

COVID-19 vaccination and lactation

A new study evaluates the presence of antibodies in breastmilk and the immune responses of lactating women after vaccination of the COVID-19 vaccine.

23 Sep 2021

Wild animals could contribute to fecal contamination in Montana backcountry lake area, study finds

Is increased human visitation to backcountry areas impacting water quality? Investigators analyzed water samples from a suite of backcountry lake outlets in the Absaroka-Beartooth Wilderness Area of Montana for fecal contamination.

23 Sep 2021

Researchers use new laser-assisted technology for bioprinting adult neuron cells

A group of researchers including a Concordia PhD student have developed a new method of bioprinting adult neuron cells. They're using a new laser-assisted technology that maintains high levels of cell viability and functionality.

22 Sep 2021

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Penn Medicine and The Wistar Institute have been awarded a prestigious $11.7 million Specialized Programs of Research Excellence, or SPORE, grant from the National Cancer Institute.

22 Sep 2021

Pinning down Pin1: Potential COVID-19 therapy

In a recent study scientists have demonstrated that Pin1 is one of the key cellular molecules necessary for SARS-CoV-2 propagation.

22 Sep 2021

SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

The study found that the delta and epsilon variants exhibited significantly higher infectivity than alpha, with delta containing approximately six times as much infectious virus for the same amount of RNA.

22 Sep 2021

Researchers seek to identify the role of hypoxia on red blood cell aging

Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension.

22 Sep 2021

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

In a recent study, RBD produced in various cell types are characterized in-depth, comparing their applicability for future COVID-19 research.

21 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

A novel FACS-based approach for SARS-CoV-2 serology

A recent study discusses a simple, sensitive, and quantitative serological test based on FACS assay to evaluate antibodies against SARS-CoV-2.

20 Sep 2021

T cell immunity induced after mild COVID could contribute to protection against re-infection

An interesting new study finds that in both adults and children, a mild infection with the SARS-CoV-2 elicits an antigen-specific memory T-cell response.

20 Sep 2021

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Guinea recently experienced its second outbreak of the Ebola virus disease within the last decade.

19 Sep 2021

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

In a study available on the preprint server medRxiv*, researchers have created a vaccine designed to overcome issues associated with attenuated-virus vaccines.

17 Sep 2021

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses

To investigate the immune memory sustainability of SARS-CoV-2-specific B cells and T cells, stimulated by the inactivated vaccine, and the potential need for a third booster dose in healthcare workers (HCWs), a non-randomized trial was undertaken by researchers at Sun Yat-sen University in Guangzhou, China. the research is posted online on the medRxiv* preprint server.

17 Sep 2021

Assay News and Research

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Further evidence of safety and efficacy of mRNA-1273 vaccine in preventing symptomatic COVID-19 and SARS-CoV-2 infection

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

Human milk antibodies elicited by vaccination show reduced activity against SARS-CoV-2 VoCs

Effect of prior SARS-CoV-2 infection on post-vaccination SARS-CoV-2 spike IgG antibodies

COVID-19 vaccination and lactation

Wild animals could contribute to fecal contamination in Montana backcountry lake area, study finds

Researchers use new laser-assisted technology for bioprinting adult neuron cells

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Pinning down Pin1: Potential COVID-19 therapy

SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

Researchers seek to identify the role of hypoxia on red blood cell aging

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

A novel FACS-based approach for SARS-CoV-2 serology

T cell immunity induced after mild COVID could contribute to protection against re-infection

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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