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Study rethinks the role of ACE2 in SARS-CoV-2 viral entry

Researchers in the US recently infected a series of human lung and head/neck cancer cell lines with SARS-CoV-2 that expressed varying levels of ACE2 and the TMPRSS2 protease to reassess their role in viral entrance.

8 Mar 2021

Push is on for states to ban organ transplant discrimination

Griffin Dalrymple is an energetic 7-year-old who loves going to school in Eureka, Montana. But two years ago, the boy described by his mother, Jayci, as a "ball of fire" was suddenly knocked back by severe bacterial pneumonia that hospitalized him for two weeks.

8 Mar 2021

In-licensed candidate may be an effective intervention for premature infants with respiratory distress syndrome

The Lundquist Institute (TLI) and The Bill & Melinda Gates Medical Research Institute (Gates MRI) executed a license agreement for TLI intellectual property covering a synthetic lung surfactant formulation to be developed for respiratory distress syndrome (RDS) for premature infants in Low- and Middle-Income countries (LMIC).

8 Mar 2021

Researchers discover how adhesions form in the abdomen

Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form.

5 Mar 2021

Fine particles in wildfire smoke more harmful to human respiratory health than other pollutants

Researchers at Scripps Institution of Oceanography at UC San Diego examining 14 years of hospital admissions data conclude that the fine particles in wildfire smoke can be several times more harmful to human respiratory health than particulate matter from other sources such as car exhaust.

5 Mar 2021

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

A recent study reports the safety and high efficacy of an adjuvanted vaccine candidate against SARS-CoV-2 and the complications of COVID-19.

5 Mar 2021

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

With a relatively minor genetic change, a new treatment developed by researchers at the Georgia Institute of Technology and Emory University appears to stop replication of both flu viruses and the virus that causes Covid-19.

4 Mar 2021

Combining terpenes and cannabidiol may be highly active against human coronaviruses

A group of researchers from a well-known technology company in Israel showed a significant antiviral effect of a combination of terpenes and cannabidiol against a human coronavirus strain 229E. This exciting and first-of-its-kind report is currently available on the bioRxiv preprint server.

4 Mar 2021

Innovative cancer treatment effective in combating fungal infection in vitro and in mice

An innovative cell-based treatment for cancer has been found promising for the control of infections caused by fungi.

4 Mar 2021

Genetic variation associated with COVID-19 outcome

Host genetics play a role in disease progression and prognosis. A paper recently uploaded to the preprint server medRxiv by Dubé et al. (1st March 2021) identifies several alleles associated with the gene natriuretic peptide receptor C (NPR3) that may impact disease severity.

3 Mar 2021

Low-cost, non-electric ventilator allows non-specialized workers to treat COVID-19 patients

A team of engineers from Loughborough University has designed and built a unique low-cost, non-electric ventilator in response to the COVID-19 pandemic.

3 Mar 2021

Cigarette smoke toxicity impacts protective biofilm in the lungs, study finds

Ben-Gurion University of the Negev Researchers (BGU) have found for the first time that cigarette smoke toxicity impacts the protective biofilm in the lungs, particularly concerning when paired with COVID-19 respiratory issues.

3 Mar 2021

Vaccine candidate shows promise to protect against dozen-plus flu strains

Ask Eric Weaver about pandemics, and he's quick to remind you of a fact that illustrates the fleeting nature of human memory and the proximal nature of human attention: The first pandemic of the 21st century struck not in 2019, but 2009.

3 Mar 2021

First detailed images of newborn babies' lungs captured at birth

Researchers have captured the first detailed images of newborn babies' lungs as they take their first breaths.

3 Mar 2021

Obesity may reduce COVID-19 vaccine efficacy, say researchers

A startling indicates that obesity may reduce the immune response to the current COVID-19 vaccines, along with other factors like age and sex. This could have significant implications for vaccination strategies in obese people.

3 Mar 2021

How SARS-CoV-2 proteins affect vascular functionality

The study, published on the pre-print server medRxiv, can pinpoint and isolate how each of the SARS-CoV-2 proteins independently affects the endothelial response and directly gauge endothelial functionality.

3 Mar 2021

SARS-CoV-2 viremia predicts severe COVID-19 disease outcomes

The SARS-CoV-2 plasma viremia has been linked to severe disease and death in COVID-19 cases in small-scale cohort studies. The current study, published on the pre-print server medRxiv, aimed to study the mechanisms behind this relationship.

2 Mar 2021

SARS-CoV-2 UK variant shows low virulence and high shedding in hamster model

A new study compares the pathogenicity and infectiousness of one such variant, the VOC 202012/01 (B.1.1.7 lineage) from the United Kingdom, with the globally dominant D614G mutation-carrying strains.

2 Mar 2021

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide

A single letter difference in a single gene, inherited from both parents, spells a lifetime of anemia and pain for 20 million people, mostly of African ancestry, worldwide.

2 Mar 2021

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New research suggests Syrian golden hamsters could be a potentially useful preclinical model for testing vaccine immunity against the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.17 and B.1.351 variant.

1 Mar 2021

Lungs News and Research

Study rethinks the role of ACE2 in SARS-CoV-2 viral entry

Push is on for states to ban organ transplant discrimination

In-licensed candidate may be an effective intervention for premature infants with respiratory distress syndrome

Researchers discover how adhesions form in the abdomen

Fine particles in wildfire smoke more harmful to human respiratory health than other pollutants

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

Combining terpenes and cannabidiol may be highly active against human coronaviruses

Innovative cancer treatment effective in combating fungal infection in vitro and in mice

Genetic variation associated with COVID-19 outcome

Low-cost, non-electric ventilator allows non-specialized workers to treat COVID-19 patients

Cigarette smoke toxicity impacts protective biofilm in the lungs, study finds

Vaccine candidate shows promise to protect against dozen-plus flu strains

First detailed images of newborn babies' lungs captured at birth

Obesity may reduce COVID-19 vaccine efficacy, say researchers

How SARS-CoV-2 proteins affect vascular functionality

SARS-CoV-2 viremia predicts severe COVID-19 disease outcomes

SARS-CoV-2 UK variant shows low virulence and high shedding in hamster model

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide

Scientists establish infection models for SARS-CoV-2 UK & South African variants

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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