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Many phase II trials overestimate drug efficacy, pose a barrier in drug licensing

Based on a systematic analysis of trials related to rheumatoid arthritis and psoriasis arthritis, a MedUni Vienna study group at the Division of Rheumatology at MedUni Vienna/Vienna General Hospital was able to show that many clinical phase II trials systematically overestimate the efficacy of therapeutics, so that the results of subsequent phase III trials can often be disappointing. Essentially this situation also applies in many other areas.

21 Apr 2020

Effects of the COVID 19 shutdown on the air quality in Innsbruck

Facing an impending shutdown due to the COVID 19 crisis, we started to document its impact on the environment by analyzing Innsbruck’s air quality with a CHARON PTR-TOF 6000 X2.

From Ionicon Analytik Ges.m.b.H. 21 Apr 2020

A promising method to diagnose sepsis with high accuracy

Whether activating or silencing genes, breaking down defective cells or building new tissue, our body is constantly working to repair itself, even in cases of illness.

21 Apr 2020

Sino Biological Partners with Nanommune Inc. to Develop and Market a Novel Coronavirus Multiplex Serological Assay

Sino Biological, Inc. today announced a co-development agreement with Nanommune Inc., an Irvine, California based biotechnology company specializing in the development and application of multiplex array technology.

From Sino Biological Inc. 21 Apr 2020

‘It hurts our soul’: Nursing home workers struggle with thankless position

In the months before county health officials ordered the evacuation of COVID-19-plagued Magnolia Rehabilitation & Nursing Center, the facility's employees complained of bounced checks.

21 Apr 2020

A new biosensor to quickly and reliably detect novel coronavirus

Jing Wang and his team at Empa and ETH Zurich usually work on measuring, analyzing and reducing airborne pollutants such as aerosols and artificially produced nanoparticles.

21 Apr 2020

Study finds NCCN Guidelines for Patients listed among the most trustworthy online resources

A recently-published study from researchers in Australia and South Africa found the NCCN Guidelines for Patients to be among the most trustworthy resources for patients and caregivers seeking information online about prostate cancer.

21 Apr 2020

Machine learning helps researchers to distinguish a rare subtype of kidney cancer

Putting together research for publication can be a challenging and time-consuming process, heightened even further because of the current COVID-19 situation, during which non-essential labs have been hibernated and many researchers are now working separately and remotely, instead of collaborating within the same space.

21 Apr 2020

The inside story of how the Bay Area got ahead of the COVID-19 crisis

Sunday was supposed to be a rare day off for Dr. Tomás Aragón after weeks of working around-the-clock.

21 Apr 2020

San Francisco quick to fight COVID-19, slow to help homeless

San Francisco Mayor London Breed has won nationwide praise for taking drastic early measures against COVID-19 that seem to have spared San Francisco the catastrophic fate of New York and other cities.

21 Apr 2020

A switch to Medicaid managed care worries some Illinois foster families

Rebecca and Bruce Austin in central Illinois have six kids — ranging in age from 4 to 22.

21 Apr 2020

How Hong Kong reduced COVID-19 transmission

Amid the coronavirus disease (COVID-19) pandemic, many countries across the globe have imposed lockdowns in an attempt to reduce the spread of the virus. Still, some countries have not opted for lockdowns, and community quarantines, and still are doing well. Hong Kong, for one, appears to have averted a major COVID-19 outbreak despite not imposing lockdown.

21 Apr 2020

Australia may beat the novel coronavirus, modeling shows

Many countries are now in lockdown in an attempt to contain the spread of the novel coronavirus, now called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus has sickened 2.47 million people worldwide, triggering many preventive measures. Now, it appears that preventive measures taken in Australia are containing the virus, according to a new modeling.

21 Apr 2020

Scientists use genomics and bioinformatics to analyze blueprint of novel coronavirus

Australian researchers from the Commonwealth Scientific and Industrial Research Organization (CSIRO) have found a new way to decode the genome of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease. This approach could help in drug and vaccine development. Their work titled, "Supporting pandemic response using genomics and bioinformatics: a case study on the emergent SARS-CoV-2 outbreak," is published in the latest issue of the journal Transboundary and Emerging Diseases.

21 Apr 2020

COVID-19 and immunodeficiency

COVID-19 disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a highly infectious disease. As of today, over 170,000 people worldwide have succumbed to the infection. Reports have shown that some comorbidities and illnesses raise the risk of getting infected and also influence the severity of the disease. Having a compromised immune system can also drastically raise the risk of getting COVID-19.

21 Apr 2020

Does high COVID-19 viral load mean more risk of infection?

The risk of getting infected with COVID-19 disease is higher among healthcare workers who are in close contact with infected patients

21 Apr 2020

Role of ACE/ARB inhibitors in the treatment of COVID-19

A new opinion piece published in the journal Circulation Research in April 2020 defends the use of antihypertensive drugs called ACE inhibitors and ARBs in patients with pandemic viral pneumonia called COVID-19.

20 Apr 2020

University of Utah invests $1.3 million in multidisciplinary COVID-19 research projects

As the COVID-19 pandemic continues to spread across the globe, University of Utah scientists are at the forefront of efforts to learn more about how to lasso the virus that causes it and understand its potential long-term social, economic, and psychological effects.

20 Apr 2020

CSIRO researchers unveil new approach to understand evolving SARS-CoV-2 virus strains

Researchers from CSIRO, Australia's national science agency, have unveiled a new approach to analyzing the genetic codes - or the blueprint - of the SARS-CoV-2 virus that causes COVID-19.

20 Apr 2020

McKelvey engineers receive federal funding for rapid COVID-19 test

Engineers at the McKelvey School of Engineering at Washington University in St. Louis have received federal funding for a rapid COVID-19 test using a newly developed technology.

20 Apr 2020