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No more ICU beds at the main public hospital in the nation’s largest county as COVID surges

She lay behind a glass barrier, heavily sedated, kept alive by a machine that blew oxygen into her lungs through a tube taped to her mouth and lodged at the back of her throat. She had deteriorated rapidly since arriving a short time earlier.

18 Dec 2020

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

A new paper that appeared as a preprint on the medRxiv* server in December 2020 describes a nucleic acid test validated on saliva samples.

18 Dec 2020

Transfer learning exploits chest-Xray to diagnose COVID-19 pneumonia

A new study from Athens, Greece, describes the use of a deep learning algorithm that uses chest X-rays to diagnose COVID-19 pneumonia.

18 Dec 2020

Pig stem cells offer a new way to grow human organs for transplantation

In a new paper published in Stem Cell Reports, Bhanu Telugu and co-inventor Chi-Hun Park of the University of Maryland (UMD) Department of Animal and Avian Sciences show for the first time that newly established stem cells from pigs, when injected into embryos, contributed to the development of only the organ of interest (the embryonic gut and liver), laying the groundwork for stem cell therapeutics and organ transplantation.

18 Dec 2020

COVID-19 particles will remain infectious as temperature begins to drop

Winter is coming in the northern hemisphere and public health officials are asking how the seasonal shift will impact the spread of SARS-CoV-2, the virus that causes COVID-19?

18 Dec 2020

Antifungal drug improves key biomarkers in the noses of patients with cystic fibrosis

A drug widely used to treat fungal infections improved key biomarkers in lung tissue cultures as well as in the noses of patients with cystic fibrosis, a clinical study by researchers at the University of Illinois Urbana-Champaign and the University of Iowa found.

17 Dec 2020

A protein may be responsible for triggering lung scarring in scleroderma patients

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

17 Dec 2020

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

Female COVID-19 patients face less severe disease complications and a lower risk of dying than male patients thanks to hormones and chromosomes that contribute to a stronger immune response, according to new research from a University of Alberta-led team.

17 Dec 2020

Study shows impact of the pandemic on lung cancer screening

When the pandemic hit the U.S. in early 2020, many routine activities came to a halt.

17 Dec 2020

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a serious chronic disease that affects the tissue surrounding the air sacs in the lungs.

17 Dec 2020

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

Study shows an inflammatory response in the mice brain is responsible for severe COVID-19

Researchers demonstrated that neuroinvasion and encephalitis caused by SARS-CoV-2 is associated with significant mortality in a special mouse model.

17 Dec 2020

Researchers examine proteins involved in SARS-CoV-2 infection

Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate.

17 Dec 2020

Researchers use bacterial strains to measure host gene expression in mouse model

The bacteria Streptococcus pneumoniae colonizes the nasopharynx and can cause pneumonia. Then, it can spread from the lungs to the bloodstream and cause organ damage.

16 Dec 2020

New study to evaluate health outcomes of SARS-CoV-2 infection in children

An observational study has launched to evaluate the short- and long-term health outcomes of SARS-CoV-2 infection in children, including multisystem inflammatory syndrome in children (MIS-C), and to characterize the immunologic pathways associated with different disease presentations and outcomes. SARS-CoV-2 is the virus that causes COVID-19.

16 Dec 2020

Lungs News and Research

No more ICU beds at the main public hospital in the nation’s largest county as COVID surges

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

Transfer learning exploits chest-Xray to diagnose COVID-19 pneumonia

Pig stem cells offer a new way to grow human organs for transplantation

COVID-19 particles will remain infectious as temperature begins to drop

Antifungal drug improves key biomarkers in the noses of patients with cystic fibrosis

A protein may be responsible for triggering lung scarring in scleroderma patients

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

Study shows impact of the pandemic on lung cancer screening

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

Study shows an inflammatory response in the mice brain is responsible for severe COVID-19

Researchers examine proteins involved in SARS-CoV-2 infection

Researchers use bacterial strains to measure host gene expression in mouse model

New study to evaluate health outcomes of SARS-CoV-2 infection in children

Scientists demonstrate a promising strategy for treating lymphomas

Research reveals two phases of infection in patients with severe COVID-19 pneumonia

LRA survey: Two-thirds of people with lupus are willing to take COVID-19 vaccine

Azithromycin trial fails to provide evidence of benefit in COVID-19

Chemical found in cigarettes could increase severity of COVID-19, new study finds

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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