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Prior COVID highly protective against severe disease ten months post-infection

In a recent study published in the Lancet, researchers performed a systematic review of scientific literature published from inception up to September 31, 2022, that documented the reduction in risk of coronavirus disease 2019 (COVID-19) among individuals with a prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection vis-à-vis those with no COVID-19 history.

19 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

Gut dysbiosis and sepsis susceptibility among pregnant women

Researchers describe the role of gut dysbiosis during pregnancy in promoting excessive macrophage pyroptosis, which increases vulnerability to sepsis.

19 Feb 2023

Cerebral autoregulation displays a daily rhythm in stroke patients

Strokes are a leading cause of morbidity and mortality in the United States, as well as around the world. Various environmental and biological factors are known to affect the risks and outcomes of strokes.

17 Feb 2023

One-third of stroke survivors experience depression

According the American Stroke Association, a division of the American Heart Association, depression is a common experience for stroke survivors.

17 Feb 2023

Epidemic dynamics of the SARS-CoV-2 Omicron variant in China during the transition from 'zero-COVID' to little-to-no intervention efforts

Researchers quantified the magnitude and rate of the SARS-CoV-2 Omicron variant outbreak in China following the abrupt exit from the ‘zero-COVID’ guidelines.

17 Feb 2023

New risk scoring system for acute type A aortic dissection to assess mortality

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Acute type A aortic dissection (ATAAD) is a catastrophic disease with fatal outcomes.

17 Feb 2023

Machine learning approach to predict cardiac surgery-associated acute kidney injury

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication that increases morbidity and mortality after cardiac surgery.

17 Feb 2023

COVID-19 virus can be detected in tears collected by swabbing, research finds

Research led by scientists at the University of São Paulo (USP) in Brazil has found that the coronavirus that causes COVID-19 can be detected in tears collected by swabbing.

16 Feb 2023

Omicron has higher risk of in-hospital mortality compared to influenza

In a recent study published in the journal JAMA Network Open, researchers compared the hospital outcomes of patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant with those of influenza patients in Switzerland, assess the current disease burden due to coronavirus disease 2019 (COVID-19).

16 Feb 2023

The kids are not OK

Teen girls "are experiencing record high levels of violence, sadness, and suicide risk," according to a new survey from the Centers for Disease Control and Prevention.

16 Feb 2023

How well are people with diabetes being supported?

A recent study published in the journal Patient Education and Counseling aimed to determine the mismatch between the actual support received and the desired level for diabetic patients. The study also evaluated this mismatch's impact on patients' health outcomes.

16 Feb 2023

How does alcohol affect blood pressure?

Drinking is part of human society worldwide. However, alcohol consumption has been strongly linked to human diseases, including dementia, liver cirrhosis, and neurological conditions. A recent research paper examined whether drinking was related to hypertension, the root factor in morbidity and mortality caused by cardiovascular disease (CVD).

16 Feb 2023

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Nirmatrelvir–ritonavir found to lower COVID-19 severity outcomes

Researchers evaluated the effectiveness of nirmatrelvir–ritonavir in preventing coronavirus disease 2019 (COVID-19) severity outcomes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant predominance.

16 Feb 2023

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Researchers performed a retrospective population-wide cohort study using anonymized data in Hong Kong, China, between February 26 and July 3, 2022.

16 Feb 2023

Post-COVID-19 CT scans show lung abnormalities persist two years later

In a recent study published in the journal Radiology, researchers longitudinally assessed changes in chest computed tomography (CT) abnormities and lung function among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Nirmatrelvir-ritonavir therapy effective against Omicron BA.4/BA.5

Researchers examine non-hospitalized adult patients with COVID-19 treated with nirmatrelvir-ritonavir.

15 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

New insights into the driving factors of COVID-19 dynamics in England

In a recent study posted to the medRxiv* preprint server, researchers provided quantitative estimates of population-level drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and infection severity by fitting coronavirus disease 2019 (COVID-19) epidemiological surveillance data from England into dynamic transmission models.

15 Feb 2023