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'Mini-brains' can be infected by SARS-CoV-2 virus

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.

30 Jun 2020

A data-rich atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in a precise symphony.

30 Jun 2020

Salk Institute expands research to find treatments and cures for COVID-19

As the COVID-19 pandemic continues across the globe, the Salk Institute joins in efforts to understand the fundamental science behind the novel coronavirus to pave the way to treatments and cures.

30 Jun 2020

Overactive neutrophils may drive life-threatening blood clots in some COVID-19 patients

Scientists have new evidence that overactive neutrophils--a common type of circulating immune cell--may drive the life-threatening blood clots and inflammation that occur in some patients with COVID-19.

29 Jun 2020

RCSI begins clinical trial of promising therapy for critically ill COVID-19 patients

Clinician scientists at RCSI University of Medicine and Health Sciences have begun a clinical trial of a promising therapy for critically ill COVID-19 patients in intensive care.

29 Jun 2020

Long-term exposure to fine atmospheric particles can lead to increased mortality rates among the elderly

A new analysis of 16 years of publicly accessible health data on 68.5 million Medicare enrollees provides broad evidence that long-term exposure to fine particles in the air - even at levels below current EPA standards - leads to increased mortality rates among the elderly.

27 Jun 2020

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after analysis of the genomes of 929 patients from the UK Biobank who had a severe response to SARS-CoV-2.

26 Jun 2020

Understanding dexamethasone’s role in treating COVID-19

While the steroid medicine dexamethasone may help people with serious COVID-19 illness, it should only be given to people very ill in hospital and shouldn’t be taken by anyone to try to prevent COVID-19 or for less severe cases.

26 Jun 2020

Groundbreaking experiment marks first successful delivery of mitochondria to liver cells

University of Connecticut researcher Dr. George Wu recently published a paper in the Journal of Gastroenterology and Hepatology outlining his successful experiment delivering mitochondria to liver cells.

25 Jun 2020

New study explores post-COVID-19 inflammatory condition in children

In recent weeks, a multisystem hyperinflammatory condition has emerged in children in association with prior exposure or infection to SARS-CoV-2.

25 Jun 2020

Platelets may be contributing to COVID-19

The current pandemic of COVID-19 is characterized mainly by severe acute respiratory distress of the lungs, but other organ dysfunctions are also being observed, including the heart and blood vessels. Now, a new paper published on the preprint server medRxiv* in June 2020 describes the abnormal activation of platelets in this disease and the link between this phenomenon and poor outcomes for COVID-19 patients.

24 Jun 2020

Bacteriophage could help decrease mortality of patients with COVID-19

Bacteriophage can reduce bacterial growth in the lungs, limiting fluid build-up. This could decrease the mortality of patients affected by COVID-19, according to the peer-reviewed journal PHAGE: Therapy, Applications, and Research.

24 Jun 2020

Statin therapy linked to lower death rate in hospitalized patients with COVID-19

The use of cholesterol-lowering drugs called statins is associated with a lower death rate and a lower incidence of mechanical ventilation in patients hospitalized with Coronavirus disease 2019 (COVID-19), researchers report June 24 in Cell Metabolism.

24 Jun 2020

Wildfire smoke has immediate effects on the body's respiratory and cardiovascular systems

Exposure to wildfire smoke affects the body's respiratory and cardiovascular systems almost immediately, according to new research from the University of British Columbia's School of Population and Public Health.

24 Jun 2020

Pangolin version of SARS-CoV-2 can cause COVID-19-like illness

The results of a recent multinational research endeavor, currently available on the bioRxiv preprint server, display the biological framework of SARS-CoV-2-related coronavirus in pangolins and reveal striking similarities to coronavirus disease (COVID-19) in humans, but also show that it can be transmitted vertically to the fetus.

23 Jun 2020

Air pollution contributes to cardiovascular disease risk in low, middle and high-income countries

From low-income countries to high-income countries, long-term exposure to fine particulate outdoor air pollution is a major contributor to cardiovascular disease and death, a new Oregon State University study found.

23 Jun 2020

Affordable and easy-to-use emergency ventilator developed for COVID-19 patients

A team of engineers and physicians at the University of California San Diego has developed a low-cost, easy-to-use emergency ventilator for COVID-19 patients that is built around a ventilator bag usually found in ambulances.

23 Jun 2020

ILC Therapeutics announces research partnership with University of St Andrews to fight against COVID-19

UK-based biotechnology firm ILC Therapeutics has announced a research partnership with the University of St Andrews in a bid to progress a therapeutic drug which can treat COVID-19 towards clinical trials.

23 Jun 2020

Single-dose Israeli vaccine candidate protective against SARS-CoV-2

Now, a new Israeli study published on the preprint server bioRxiv in June 2020 reports a new recombinant vaccine expressing the S or spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to be highly protective with a single dose in an animal model. This could be a gamechanger in the fight to contain the outbreak.

23 Jun 2020

Prior infection provides protection against SARS-CoV-2 virus in hamsters

In an animal model for COVID-19 that shares important features of human disease, scientists at the University of Wisconsin–Madison, the University of Tokyo and the Icahn School of Medicine at Mount Sinai show that prior infection with the SARS-CoV-2 virus provides protection against reinfection, and treatment with convalescent serum limits virus replication in their lungs.

22 Jun 2020

Lungs News and Research

'Mini-brains' can be infected by SARS-CoV-2 virus

A data-rich atlas of the developing human brain

Salk Institute expands research to find treatments and cures for COVID-19

Overactive neutrophils may drive life-threatening blood clots in some COVID-19 patients

RCSI begins clinical trial of promising therapy for critically ill COVID-19 patients

Long-term exposure to fine atmospheric particles can lead to increased mortality rates among the elderly

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

Understanding dexamethasone’s role in treating COVID-19

Groundbreaking experiment marks first successful delivery of mitochondria to liver cells

New study explores post-COVID-19 inflammatory condition in children

Platelets may be contributing to COVID-19

Bacteriophage could help decrease mortality of patients with COVID-19

Statin therapy linked to lower death rate in hospitalized patients with COVID-19

Wildfire smoke has immediate effects on the body's respiratory and cardiovascular systems

Pangolin version of SARS-CoV-2 can cause COVID-19-like illness

Air pollution contributes to cardiovascular disease risk in low, middle and high-income countries

Affordable and easy-to-use emergency ventilator developed for COVID-19 patients

ILC Therapeutics announces research partnership with University of St Andrews to fight against COVID-19

Single-dose Israeli vaccine candidate protective against SARS-CoV-2

Prior infection provides protection against SARS-CoV-2 virus in hamsters

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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