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Inside the tactical tug of war over the controversial Alzheimer’s drug

The drug industry, patient advocates, and congressional Republicans have all attacked federal officials' decision to decline routine Medicare coverage for a controversial Alzheimer's drug.

16 Feb 2022

Omicron RBD-ACE2 binding found to be stronger than wild type SARS-CoV-2 strain

Researchers recently investigated the effect of SARS-CoV-2 Omicron variant mutations on the binding of the receptor-binding domain and angiotensin-converting enzyme-2 to study the overall binding profile of the RBD-ACE2 system.

16 Feb 2022

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Researchers investigated the role of platelets in the adverse immune response against a COVID-19 vaccine.

16 Feb 2022

Study shows mRNA COVID-19 vaccination in pregnancy can prevent hospitalization among infants

A report published in the CDC’s Morbidity and Mortality Weekly Report (MMWR) shows how primary two-dose vaccination series against coronavirus disease 2019 (COVID-19) during pregnancy is linked to a reduced risk of COVID-19–associated hospitalization among infants six months of age or younger.

16 Feb 2022

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

Preclinical models that recapitulate aspects of human airway disease are essential for the advancement of novel therapeutics and vaccines.

16 Feb 2022

Superior immune response in vaccinated after infection with Omicron compared to unvaccinated

In a recent study posted to the medRxiv* preprint server, researchers evaluated the cross-reactivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant-triggered neutralization and fragment crystallizable (Fc) effector functions between coronavirus disease 2019 (COVID-19)-vaccinated and unvaccinated individuals in South Africa.

16 Feb 2022

The long-term consequences of SARS-CoV-2 infection in people with HIV

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from the United States (US) analyzed a cohort of patients with human immunodeficiency virus (HIV) (PWH) recovering from coronavirus disease 2019 (COVID-19) and characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune responses in these patients.

15 Feb 2022

Neutralizing antibody levels to different SARS-CoV-2 epitopes fluctuate over time

Researchers study antibodies against various SARS-CoV-2 epitopes that may be responsible for neutralizing activities in recovered COVID-19 patients.

15 Feb 2022

Post-vaccination titers of neutralizing antibodies revealed as a moderate predictor of vaccine-induced immunity

In a new study, researchers investigated whether neutralizing antibodies against the SARS-CoV-2 spike protein offered adequate immunity against breakthrough infections among vaccinated individuals.

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

A recent study described COVID-19 sequelae developed in non-hospitalized young adults more than six months after COVID-19 infection.

15 Feb 2022

Novel glycation patterns help understand Omicron immune escape

A new study explores changes in the sugar structure of the SARS-CoV-2 Omicron variant, which may shed light on its immunologic escape and transmissibility characteristics.

15 Feb 2022

South African population reveal durable protection by prior infection against pre-Omicron variants

A recent study explored the buildup of immunity developed post-SARS-CoV-2 infection in African people and the impact of SARS-CoV-2 Omicron VOC on the COVID-19 pandemic.

15 Feb 2022

Study explores SARS-CoV-2 antibodies in children

Researchers set out to explore how COVID-19 antibody responses persist over time after natural infection in children.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

In a recent study posted to the bioRxiv* preprint server, a team of researchers from Washington, United States, investigated the transmission of viral genetic diversity during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading outbreak among the crew members on a fishing boat.

14 Feb 2022

Antibodies News and Research

Inside the tactical tug of war over the controversial Alzheimer’s drug

Omicron RBD-ACE2 binding found to be stronger than wild type SARS-CoV-2 strain

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Study shows mRNA COVID-19 vaccination in pregnancy can prevent hospitalization among infants

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

Superior immune response in vaccinated after infection with Omicron compared to unvaccinated

The long-term consequences of SARS-CoV-2 infection in people with HIV

Neutralizing antibody levels to different SARS-CoV-2 epitopes fluctuate over time

Post-vaccination titers of neutralizing antibodies revealed as a moderate predictor of vaccine-induced immunity

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

Novel glycation patterns help understand Omicron immune escape

South African population reveal durable protection by prior infection against pre-Omicron variants

Study explores SARS-CoV-2 antibodies in children

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Real-world data on efficacy and safety of COVID vaccines in Canada

First survey on Omicron BA.2 in France

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

A new way of characterising biomolecules eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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