Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information to make decisions about patient care.

8 Aug 2022

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells (β cells)-;cells in the pancreas that produce and distribute insulin.

4 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

3 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN-Bio 3 Aug 2022

International travel restrictions were a key intervention for slowing COVID-19 spread, study shows

A study of COVID-19 variant transmission into and across Canada shows that international travel restrictions were a key intervention for reducing or slowing spread, according to a report published today in eLife.

2 Aug 2022

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

While infants exposed to opioids during their mother's pregnancy have been linked to adverse health outcomes, a new study at the University of Missouri has found prenatal opioid exposure could trigger long-term neurological or behavioral effects later in a child's life.

29 Jul 2022

Automation of established method for isolating volatile food ingredients

A research team from the Leibniz Institute for Food Systems Biology at the Technical University of Munich (LSB) has succeeded in automating an established method for the gentle, artifact-avoiding isolation of volatile food ingredients.

29 Jul 2022

Nonfungible tokens may help overcome the ethical challenges for secondary use of biospecimens

JMIR Publications recently published "Nonfungible Tokens as a Blockchain Solution to Ethical Challenges for the Secondary Use of Biospecimens: Viewpoint" in JMIR Bioinformatics and Biotechnology in which the authors discuss how current practices of de-identifying human samples for research is reminiscent of the treatment of Henrietta Lacks's tissue in 1951.

29 Jul 2022

Researchers pinpoint multiple zoonotic origins of SARS-CoV-2

In a pair of related studies, published July 26, 2022 online via First Release in Science, researchers at University of California San Diego, with colleagues on four continents, show that the origin of the COVID-19 pandemic in 2019 was at the Huanan Seafood Wholesale Market in Wuhan, China, and resulted from at least two instances of the SARS-CoV-2 virus jumping from live animal hosts to humans working or shopping there.

26 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

New way to test vaccines may be as rigorous and stringent as exposure to field strains of malaria

Malaria is the deadliest mosquito-borne parasitic infection of humans. In 2021, after a century of research, the World Health Organization (WHO) approved the world's first malaria vaccine.

20 Jul 2022

Identifying a core human microbiome

Researchers provide a critical review of the concept of the core human microbiome.

19 Jul 2022

Grant funds research that investigates relationships between certain fungi and specific cancers

Dr. Iliyan D. Iliev, an associate professor of immunology and microbiology in the Division of Gastroenterology and Hepatology and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease at Weill Cornell Medicine, has been awarded a five-year, $1.25 million CRI Lloyd J. Old STAR (Scientists Taking Risks) Program grant from Cancer Research Institute (CRI).

19 Jul 2022

Study offers new insights into brain metastases in patients with melanoma

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

Researchers assessed the impact of the vaccinia virus vaccine on the immune response against the monkeypox virus.

12 Jul 2022

Bioinformatics News and Research

Further Reading

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

CHOP helps launch new computational platform to harmonize pediatric cancer data

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

International travel restrictions were a key intervention for slowing COVID-19 spread, study shows

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

Automation of established method for isolating volatile food ingredients

Nonfungible tokens may help overcome the ethical challenges for secondary use of biospecimens

Researchers pinpoint multiple zoonotic origins of SARS-CoV-2

Study identifies risks in the use of CRISPR therapeutics

New way to test vaccines may be as rigorous and stringent as exposure to field strains of malaria

Identifying a core human microbiome

Grant funds research that investigates relationships between certain fungi and specific cancers

Study offers new insights into brain metastases in patients with melanoma

Frequent, regular rapid antigen testing plus isolation could cut COVID-19 risk among groups of people

New high-throughput genomic array offers an in-depth view of the mouse epigenome

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

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