Antibodies News and Research

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Vaccine-induced immune responses for SARS-CoV-2 in patients receiving anti-CD20 B-cell depleting therapies

A new study published on the medRxiv* preprint server analyzed the trajectories of anti-SARS-CoV-2 antibodies in patients from the RituxiVac study were compared to healthy volunteers. In addition, they investigated the immunogenicity of a third vaccine dose in previously non-responding patients.

23 Nov 2021

Higher antibody level correlates with greater vaccine protection against COVID-19

By measuring antibodies against the SARS-CoV-2 spike protein in participants in a phase 3 trial of the Moderna COVID-19 vaccine, researchers found that the higher the antibody level, the greater the vaccine protection against COVID-19.

23 Nov 2021

Mouthwash containing an antiviral phthalocyanine derivative shortens hospitalizations due to COVID-19

In a study published in the journal Scientific Reports, a research group from Brazil showed how antiviral anionic phthalocyanine derivative used in a mouthwash protocol may not only reduce the symptoms of coronavirus disease (COVID-19), but also hamper the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

Researchers discuss two cases of MIS-V after the patients had received the SARS-CoV-2 vaccine from Pfizer/BioNTech (BNT162b2).

23 Nov 2021

Strong antibody responses against harmless coronaviruses may protect against SARS-CoV-2

Infections with the novel coronavirus and vaccination lead to strong antibody responses against SARS-CoV-2. Immune responses to other human coronaviruses, which mostly only cause harmless colds, also provide some protection against SARS-CoV-2.

23 Nov 2021

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Scientists utilize N. benthamiana for producing the N-protein and an antigenic cocktail containing the N-protein and SARS-CoV-2 S RBD.

23 Nov 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

Inactivated virion-based vaccine confers robust cell-mediated immunity against major SARS-CoV-2 variants

Indian researchers determine the magnitude, quality, and persistence of cellular and humoral memory responses after vaccination with BBV152/Covaxin.

23 Nov 2021

WHO’s C-TAP and MPP finalize licensing agreement with CSIC for COVID-19 serological antibody technology

WHO's COVID-19 Technology Access Pool and the Medicines Patent Pool today finalized a licensing agreement with the Spanish National Research Council for a COVID-19 serological antibody technology.

23 Nov 2021

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

In a study recently published on the bioRxiv* preprint server, researchers investigated the IFITM2 dependency of SARS-CoV-2 VOCs, including the delta variant for efficient infection.

22 Nov 2021

Characterization of B-cell receptor repertoires in COVID-19 patients

In a new study published in the journal Human Immunology, scientists sought to better understand how B-cell immune repertoire changes over time during SARS-CoV-2 infection by comprehensively characterizing the dynamics of immunoglobin heavy chain (IGH) repertoire in COVID-19 patients.

22 Nov 2021

Researchers make progress towards a new diagnostic test for schistosomiasis

Researchers have made important progress towards a new diagnostic test for schistosomiasis, which could help the World Health Organization achieve its goal of interrupting transmission of the disease, and eventually eliminating it.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

SARS-CoV-2 infection risk in Norwegian fitness centers

Researchers from the University of Oslo oversaw a trial in Norway in which several fitness centers were allowed to open.

22 Nov 2021

COVID-19 multistate outbreak associated with large public gatherings

Researchers from the Centers for Disease Control have investigated a case in Massachusetts that showed a high proportion of vaccine breakthrough infections.

22 Nov 2021

Study finds no increased risk of severe COVID-19 in immunocompromised children in UK

Researchers conducted a prospective study to describe the incidence and clinical spectrum of SARS-CoV-2 infection in a UK-wide cohort of immunocompromised children.

22 Nov 2021

Success of covid antiviral pills hinges on access to speedy and accurate tests

Within a few weeks, perhaps before many Americans finish decorating for the holidays, the U.S. could have access to a new antiviral pill from Merck expected to alter the deadly trajectory of the covid-19 pandemic — with a second option from Pfizer to follow shortly after.

22 Nov 2021

CoronaVac vaccine booster strengthens protection against SARS-CoV-2

In a recent study published on the preprint medRxiv* server, an international team of scientists tested CoronaVac as a booster shot and measured its effects on immunity. Their findings showed increases in neutralizing antibodies and T cell response.

21 Nov 2021

Scientists discover several factors influencing waning immunity with the Pfizer COVID Vaccine

New research from Japan found several risk factors associated with greater waning immunity after vaccination. Old age and smoking were amongst those with some of the lowest antibody titers. Women more than men were also more likely to experience a rapid decline in antibody levels 3 to 6 months after receiving their second Pfizer-BioNTech dose.

21 Nov 2021

Antibodies News and Research

Vaccine-induced immune responses for SARS-CoV-2 in patients receiving anti-CD20 B-cell depleting therapies

Higher antibody level correlates with greater vaccine protection against COVID-19

Mouthwash containing an antiviral phthalocyanine derivative shortens hospitalizations due to COVID-19

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

Strong antibody responses against harmless coronaviruses may protect against SARS-CoV-2

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Inactivated virion-based vaccine confers robust cell-mediated immunity against major SARS-CoV-2 variants

WHO’s C-TAP and MPP finalize licensing agreement with CSIC for COVID-19 serological antibody technology

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

Characterization of B-cell receptor repertoires in COVID-19 patients

Researchers make progress towards a new diagnostic test for schistosomiasis

Paper-based innovations for COVID-19 diagnosis

SARS-CoV-2 infection risk in Norwegian fitness centers

COVID-19 multistate outbreak associated with large public gatherings

Study finds no increased risk of severe COVID-19 in immunocompromised children in UK

Success of covid antiviral pills hinges on access to speedy and accurate tests

CoronaVac vaccine booster strengthens protection against SARS-CoV-2

Scientists discover several factors influencing waning immunity with the Pfizer COVID Vaccine

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