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Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

A German case study recently published in the journal Nature Communications has characterized a long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection dynamics in an immunosuppressed kidney transplant recipient and provided evidence for the evolution of SARS-CoV-2 into potentially harmful immune escape mutants during persistent infections.

10 Nov 2021

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy.

10 Nov 2021

Coronaviruses synthesize RNA in membrane-bound compartments

A team of researchers show that IBV viral RNA synthesis occurs within the membrane-bound compartment

10 Nov 2021

The immune response elicited by an inactivated SAR-CoV-2 vaccine

A team of researchers assessed antibody responses to the inactivated SARS-CoV-2 vaccine among vaccine recipients in Shenzhen, China.

10 Nov 2021

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

A new study finds improved Fc cross-reactivity against certain SARS-CoV-2 variant of concern.

10 Nov 2021

Chronological changes in SARS-CoV-2 immune responses after BNT162b2 vaccine

A new study focused on the chronological changes in humoral and cell-mediated immune responses, during and after the BNT162b2 vaccine administration, among hospital workers of a national medical institution in Japan.

10 Nov 2021

Mechanism of SARS-CoV-2 antibody transfer into breastmilk

A recent study aimed to understand better the mechanism of antibody transfer to breastmilk in the setting of SARS-CoV-2 infection.

10 Nov 2021

Mechanisms and strategies for antibody binding and escape in SARS-CoV-2

A new study investigated the mechanisms for binding and strategies to escape several hNAbs used by SARS-CoV-2 strains through molecular simulations.

10 Nov 2021

The impact of interventions and contact patterns on SARS-CoV-2 transmission

A recent study investigates the impact of varying interventions, consequent contact patterns, and the transmissibility of SARS-CoV-2.

9 Nov 2021

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

A new study explores the potential of MV-based vaccines targeting the S protein of SARS-CoV-2.

9 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

The current study from Israel discusses the change in antibody response with the trimester of infection and the infecting variant.

9 Nov 2021

SARS-CoV-2 infection in white-tailed deer

In the current study, SARS-CoV-2 antibodies were identified in over a third of free-ranging deer in northeast Ohio.

9 Nov 2021

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Researchers from the University of Toronto set out to create a new tetravalent antibody that could bind with enough potency that it could remain effective against VOCs.

9 Nov 2021

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Researchers from VaxiGen have been investigating the potential for a DNA vaccine boost to VP vaccines against coronavirus disease 2019.

9 Nov 2021

Drinking alcohol and not exercising are modifiable risk factors for SARS-CoV-2

New research from the United Kingdom suggests several factors that increased the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involved higher alcohol use, Asian/Asian British ethnicity, and obesity. In addition, moderate but not vigorous exercise of more than 10 hours a week was associated with lower susceptibility to infection.

8 Nov 2021

Increase in SARS-CoV-2 seroprevalence in Irish HCWs during third wave of pandemic

Healthcare workers and people they live with are at an increased risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Hospital healthcare workers (HCWs) worldwide have been found to have a higher number of SARS-CoV-2 infections and higher antibody seroprevalence compared to the general population.

8 Nov 2021

Scientists develop a high-throughput, cell-free screening platform for anti-SARS-CoV-2 antibody discovery

Scientists from Northwestern University, USA, have recently developed a high-throughput, automated screening platform to rapidly identify anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. The study is currently available on the bioRxiv* preprint server.

8 Nov 2021

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma.

8 Nov 2021

Antibodies News and Research

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Coronaviruses synthesize RNA in membrane-bound compartments

The immune response elicited by an inactivated SAR-CoV-2 vaccine

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

Chronological changes in SARS-CoV-2 immune responses after BNT162b2 vaccine

Mechanism of SARS-CoV-2 antibody transfer into breastmilk

Mechanisms and strategies for antibody binding and escape in SARS-CoV-2

The impact of interventions and contact patterns on SARS-CoV-2 transmission

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

SARS-CoV-2 infection in white-tailed deer

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Drinking alcohol and not exercising are modifiable risk factors for SARS-CoV-2

Increase in SARS-CoV-2 seroprevalence in Irish HCWs during third wave of pandemic

Scientists develop a high-throughput, cell-free screening platform for anti-SARS-CoV-2 antibody discovery

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

How to make hybridoma-based antibody discovery more efficient eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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