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Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Researchers investigate clinical epidemiological impact of Omicron among hospitalized COVID-19 patients

Researchers assessed the global impact of the emergence of the SARS-CoV-2 Omicron variant on COVID-19 clinical epidemiology among hospitalized patients.

27 Jun 2022

Bisphosphonates appear to improve COVID-19 exposure outcomes

A new retrospective study examines the effect of bisphosphonates on COVID-19 outcomes.

27 Jun 2022

Study finds higher risk of premature death among patients with pediatric onset immune-mediated inflammatory disease

Patients with a pediatric onset immune-mediated inflammatory disease have a significantly higher risk of premature death, according to new research being presented today at the 54th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition.

26 Jun 2022

Study quantifies the cardiovascular risk posed by specific environmental exposures

A new study from the Icahn School of Medicine at Mount Sinai quantifies the cardiovascular risk posed by exposure to specific environmental factors, showing, for example, that air pollution heightens the risk of heart disease mortality by 17 percent.

24 Jun 2022

Biodegradable nanomaterials can take images and deliver medicine to combat peripheral arterial disease

A University of Texas at Arlington bioengineer is leading a project that will develop biodegradable nanomaterials that will take pictures and deliver medicine to combat peripheral arterial disease (PAD).

24 Jun 2022

Researchers report high rates of new TB infection among adolescents in Tanzania

Published today in PLOS ONE, "Serial T-SPOT.TB responses in Tanzanian adolescents: transient, persistent and irregular conversions" [https://doi.org/10.1371/journal.pone.0268685], investigators from the Geisel School of Medicine and Muhimibili University of Health and Allied Sciences report high rates of new tuberculosis (TB) infection among adolescents in Tanzania.

24 Jun 2022

Environmental factors are highly predictive of people's risk of death, study shows

Along with high blood pressure, diabetes, and smoking, environmental factors such as air pollution are highly predictive of people's chances of dying, especially from heart attack and stroke, a new study shows.

24 Jun 2022

Updated Cochrane Review: No evidence to support the use of ivermectin for treating COVID-19 infection

There remains no evidence to support the use of ivermectin for treating or preventing COVID-19 infection, state the authors of an updated Cochrane Review, which now contains 11 trials across 3409 people.

24 Jun 2022

Seniors with prediabetes should eat better, get moving, but not fret too much about diabetes

Almost half of older adults — more than 26 million people 65 and older — have prediabetes, according to the Centers for Disease Control and Prevention. How concerned should they be?

24 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

Largest study on longevity reveals secrets of reptile and amphibian aging

At 190 years old, Jonathan the Seychelles giant tortoise recently made news for being the "oldest living land animal in the world."

23 Jun 2022

Women less likely to receive timely treatment for heart attack despite improvements to care

Despite overall improvements to care for a heart attack, women are less likely to receive timely treatment, according to a new study in Annals of Emergency Medicine.

23 Jun 2022

Is the ability to complete a 10- second one-legged stance associated with all-cause mortality?

Researchers investigated the association between a complete 10-second one-legged stance and all-cause mortality.

23 Jun 2022

Addressing parents' hesitancy to vaccinate their children against COVID

Researchers examine notable risk factors related to vaccine hesitancy among parents.

23 Jun 2022

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

A recent work posted to the bioRxiv* preprint server assessed the indicators of anamnestic humoral immunity among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

23 Jun 2022

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

In a recent study published in the Cochrane Library, researchers searched multiple databases to identify randomized controlled trials (RCTs) that evaluated severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐neutralizing monoclonal antibodies (mAbs).

23 Jun 2022

Paxlovid is shown to be effective in treating COVID-19

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers described cases of coronavirus disease 2019 (COVID-19)–related hospitalizations and emergency department (ED) visits in five to 15 days following Paxlovid (Nirmatrelvir/ritonavir ) treatment.

22 Jun 2022

Quality of care, outcomes for stroke patients in VA's health system did not decline during the COVID-19 pandemic

In one of the first studies to investigate the overall quality of care and outcomes of stroke care for non-COVID-19 hospitalized patients during the pandemic from a national U.S. perspective, researchers from the U.S. Department of Veterans Affairs (VA), Regenstrief Institute and Monash University assessed patients with strokes and transient ischemic attacks (often called mini-strokes or TIAs) in 128 hospitals across the U.S. in the VA's health system, the nation's largest integrated healthcare system.

22 Jun 2022

Scientists evaluate JNK inhibitors in treating moderate to severe COVID-19 patients

Scientists have described the clinical outcomes in hospitalized COVID-19 patients who have been treated with JNK inhibitors together with standard of care.

22 Jun 2022

Mortality News and Research

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Researchers investigate clinical epidemiological impact of Omicron among hospitalized COVID-19 patients

Bisphosphonates appear to improve COVID-19 exposure outcomes

Study finds higher risk of premature death among patients with pediatric onset immune-mediated inflammatory disease

Study quantifies the cardiovascular risk posed by specific environmental exposures

Biodegradable nanomaterials can take images and deliver medicine to combat peripheral arterial disease

Researchers report high rates of new TB infection among adolescents in Tanzania

Environmental factors are highly predictive of people's risk of death, study shows

Updated Cochrane Review: No evidence to support the use of ivermectin for treating COVID-19 infection

Seniors with prediabetes should eat better, get moving, but not fret too much about diabetes

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

Largest study on longevity reveals secrets of reptile and amphibian aging

Women less likely to receive timely treatment for heart attack despite improvements to care

Is the ability to complete a 10- second one-legged stance associated with all-cause mortality?

Addressing parents' hesitancy to vaccinate their children against COVID

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

Paxlovid is shown to be effective in treating COVID-19

Quality of care, outcomes for stroke patients in VA's health system did not decline during the COVID-19 pandemic

Scientists evaluate JNK inhibitors in treating moderate to severe COVID-19 patients

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