Immune System News and Research

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COVID-19 recovered vaccinated individuals more protected from Delta variant

The B.1.617 lineage of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in October 2020, has led to new outbreaks of the infection and new waves of the pandemic. This infectious lineage has resulted in the generation of sub-lineages such as B.1.617.1 (Kappa), B.1.617.2 (Delta) and B.1.617.3.

6 Jul 2021

What are predictive biomarkers of COVID-19 disease severity in pregnant women?

In a paper recently published in the Nature journal Scientific Reports, a retrospective cohort study on inflammatory biomarkers in pregnant women with COVID-19 reveals key differences that could better allow an accurate COVID-19 prognosis to be attained in pregnant women.

5 Jul 2021

Exposure to beneficial microorganisms is not affected by targeted hygiene or cleaning

The theory that modern society is too clean, leading to defective immune systems in children, should be swept under the carpet, according to a new study by researchers at UCL and the London School of Hygiene & Tropical Medicine.

5 Jul 2021

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Gaurav Gaiha, MD, DPhil, a member of the Ragon Institute of MGH, MIT and Harvard, studies HIV, one of the fastest-mutating viruses known to humankind.

2 Jul 2021

Research points towards macropinocytosis as a target for future cancer treatment

It is the membrane of cancer cells that is at the focus of the new research now showing a completely new way in which cancer cells can repair the damage that can otherwise kill them.

2 Jul 2021

NYU Abu Dhabi researchers use NMR spectroscopy to map the structure of specific nanobody

For the first time in the UAE, researchers at NYU Abu Dhabi have used nuclear magnetic resonance techniques to determine the structure of a specific nanobody, Nb23, potentially leading to a better understanding of how this small protein derived from an antibody type, found only in camelids (i.e camels, llamas, and alpacas) and sharks, can fight diseases ranging from rheumatoid arthritis, lupus and psoriasis to lymphoma and breast cancer.

2 Jul 2021

Research pinpoints a molecular component responsible for modulating flu damage

New experimental data pinpoints a molecular component responsible for modulating the damage the flu can wreck on the lungs.

2 Jul 2021

The use of flavonoids as antiviral agents against SARS-CoV-2

Researchers in Iran have undertaken a comprehensive review of flavonoids and their antiviral potential against SARS-CoV-2.

2 Jul 2021

New immunotherapy treatment for cancer patients is more effective and less dangerous

Cell toxicity during immunotherapy is a major limitation to cancer treatment.

2 Jul 2021

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Evidence continues to mount that vaccination against COVID-19, most notably the Pfizer and Moderna vaccines, produces robust, durable protection in the vast majority of recipients.

2 Jul 2021

Experts reveal ways of dealing with fear and provide scope for confidence

Terrorism, climate change and now a pandemic - worries and fears shape the everyday lives of many people. The latest issue of the Science Magazine BfR2GO from the German Federal Institute for Risk Assessment (BfR) is dedicated to fear, while at the same time embarking on a search for confidence. Scientists from many spheres have their chance to speak and categorize the concepts in a clear way.

2 Jul 2021

Vaccines grown in eggs can lead to an off-target antibody response

Over years of studying antibody responses against the flu in the Wilson lab at the University of Chicago, researchers kept coming up with a strange finding: antibodies that seemed to bind not only to the flu virus but to every virus the lab could throw at them.

2 Jul 2021

Is there a link between circadian rhythms and COVID-19 severity?

This study showed that the time of day of SARS-CoV-2 infection could impact the severity of the viral infection and the host immune response.

1 Jul 2021

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

A team of researchers recently demonstrated that mutations in the S protein of SARS-CoV-2 select for amino acid changes that result in a more stable protein than would otherwise be expected.

1 Jul 2021

Cryo-EM structure of neutralizing antibody 5-7 in complex with SARS CoV-2 spike

Researchers from the US recently reported the 3.7 Å resolution cryo-EM structure of an NTD-directed neutralizing antibody 5-7 that forms a complex with SARS-CoV-2 spike protein. They also presented the neutralization data against VOC and studied the recognized epitope.

1 Jul 2021

Immune System News and Research

COVID-19 recovered vaccinated individuals more protected from Delta variant

What are predictive biomarkers of COVID-19 disease severity in pregnant women?

Exposure to beneficial microorganisms is not affected by targeted hygiene or cleaning

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Research points towards macropinocytosis as a target for future cancer treatment

NYU Abu Dhabi researchers use NMR spectroscopy to map the structure of specific nanobody

Research pinpoints a molecular component responsible for modulating flu damage

The use of flavonoids as antiviral agents against SARS-CoV-2

New immunotherapy treatment for cancer patients is more effective and less dangerous

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Experts reveal ways of dealing with fear and provide scope for confidence

Vaccines grown in eggs can lead to an off-target antibody response

Is there a link between circadian rhythms and COVID-19 severity?

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

Cryo-EM structure of neutralizing antibody 5-7 in complex with SARS CoV-2 spike

High levels of neutrophil extracellular traps found in airways of severely ill Covid-19 patients

Study highlights the importance of T cell cross reactivity in stopping severe COVID-19 infections

Scientists uncover features of T cells that distinguish fatal COVID-19 from non-fatal cases

Lung cancer patients should be screened for MET oncogene amplification, research suggests

Study evaluates neutralizing antibody responses elicited by the Pfizer/BioNTech COVID-19 vaccine

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