Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Applying a form of AI to sift through large amounts of biological data

Researchers at the University of Missouri are applying a form of artificial intelligence (AI) -; previously used to analyze how National Basketball Association (NBA) players move their bodies -; to now help scientists develop new drug therapies for medical treatments targeting cancers and other diseases.

6 May 2022

Marine bioactive compounds against SARS-CoV-2

A new review paper published in the journal Environmental Science and Pollution Research aimed to determine the possibilities of using biologically active compounds derived from various chemical classes of marine organisms against SARS-CoV-2 infection at various stages of the life cycle of the virus.

6 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Researchers demonstrate the efficiency of T-cell immune response against the Omicron variant

Scholars from HSE University and the RAS Institute of Bioorganic Chemistry have demonstrated the efficiency of T-cell immune response against the Omicron variant of SARS-CoV-2.

28 Apr 2022

Could DNA be linked to Premature Aging in Cancer Survivors?

In this interview, we speak to Dr. Wang about his latest research that investigated accelerated aging in childhood cancer survivors and the underlying genetics causing this.

22 Apr 2022

Salk scientists identify a protein that is critical for preventing pancreatic auto-digestion in mice

Every day, your pancreas produces about one cup of digestive juices, a mixture of molecules that can break down the food you eat.

21 Apr 2022

DNA analysis of tumors uncovers a 'treasure trove' of clues about the causes of cancer

DNA analysis of thousands of tumors from NHS patients has found a 'treasure trove' of clues about the causes of cancer, with genetic mutations providing a personal history of the damage and repair processes each patient has been through.

21 Apr 2022

Researchers discover more needles in the haystack in the quest to unravel Alzheimer’s disease

21 million. That's the number of genetic variations in the human genome that researchers are sifting to identify patterns predisposing people to Alzheimer's disease.

20 Apr 2022

Acquiring real-time, accurate and reproducible 4D bioinformatics data with PaSER

In this interview, Chris Adams Ph.D., Business Development Director, Global Bioinformatics, Life Science Mass Spectrometry at Bruker Daltonics, Billerica, MA, USA talks to News-Medical Life Sciences about acquiring real-time, accurate and reproducible 4D-proteomics data with PaSER.

From Bruker Life Sciences Mass Spectrometry 20 Apr 2022

Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Report provides recommendations to help prevent or mitigate economic challenges during future public health emergencies

The Association for Molecular Pathology, the premier global, molecular diagnostic professional society, today released a report entitled "Economics of Clinical Testing during a Public Health Emergency: Lessons Learned from Two Years of COVID-19."

19 Apr 2022

Wearables can identify changes in physiological systems during COVID-19 disease progression

If you become ill with COVID-19, your smartwatch can track the progression of your symptoms, and could even show how sick you become.

19 Apr 2022

Researchers investigate COVID-19 data with logistic regression model training

A new study investigated how logistic regression model training affects performance, and which features are best to include when examining datasets from individuals suffering from COVID-19.

19 Apr 2022

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have developed a new bioinformatics platform that predicts optimal treatment combinations for a given group of patients based on co-occurring tumor alterations.

12 Apr 2022

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

New findings from the ongoing Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study suggest that certain rheumatoid arthritis drugs may lower incidence of Alzheimer's disease and related dementias in people with cardiovascular disease.

8 Apr 2022

Researchers develop universal AI algorithm to "clean" noisy single-cell RNA sequencing data

Just as asking a single person about their health will provide tailored, personalized information impossible to glean from a large poll, an individual cell's genome or transcriptome can provide much more information about their place in living systems than sequencing a whole batch of cells.

7 Apr 2022

Researchers obtain a treasure trove of new data about RNA viruses from ocean water samples

Ocean water samples collected around the world have yielded a treasure trove of new data about RNA viruses, expanding ecological research possibilities and reshaping our understanding of how these small but significant submicroscopic particles evolved.

7 Apr 2022

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

In a recent study published in the journal PLOS Genetics, researchers explored severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) editing in host cells.

4 Apr 2022

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

In a paper in the journal Nature, Los Alamos National Laboratory scientists Bette Korber, Hyejin Yoon, Will Fischer and James Theiler, among nearly 130 authors from institutions around the world, describe their groundbreaking collaborative work, "Defining the risk of SARS-CoV-2 variants on immune protection."

1 Apr 2022

Bioinformatics News and Research

Further Reading

Applying a form of AI to sift through large amounts of biological data

Marine bioactive compounds against SARS-CoV-2

Researchers create models to study brain metastases that recapitulate the disease

Researchers demonstrate the efficiency of T-cell immune response against the Omicron variant

Could DNA be linked to Premature Aging in Cancer Survivors?

Salk scientists identify a protein that is critical for preventing pancreatic auto-digestion in mice

DNA analysis of tumors uncovers a 'treasure trove' of clues about the causes of cancer

Researchers discover more needles in the haystack in the quest to unravel Alzheimer’s disease

Acquiring real-time, accurate and reproducible 4D bioinformatics data with PaSER

Little-known protein found to play a role in common neurodegenerative disorder

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

Report provides recommendations to help prevent or mitigate economic challenges during future public health emergencies

Wearables can identify changes in physiological systems during COVID-19 disease progression

Researchers investigate COVID-19 data with logistic regression model training

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

Researchers develop universal AI algorithm to "clean" noisy single-cell RNA sequencing data

Researchers obtain a treasure trove of new data about RNA viruses from ocean water samples

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

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