Cancer Immunotherapy News and Research

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Specialized proteins could soak up excess cytokines in COVID-19 patients

One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

16 Apr 2020

Molecular pathway that controls immunosuppression in tumors identified

An active immune system plays an important role in stopping cancer progression by identifying tumor cells and targeting them for destruction. Any deviation in the normal activities of the immune system could lead to accelerated tumor growth.

14 Apr 2020

Supercomputer helps benchmark new molecular docking tool

With the American Cancer Society estimating 1.76 million new cases and more than 600,000 deaths during 2019 in the U.S. alone, cancer remains a critical healthcare challenge.

25 Mar 2020

Immunotherapy combination can shrink viral reservoir in HIV model

Stimulating immune cells with two cancer immunotherapies together can shrink the size of the viral "reservoir" in SIV-infected non-human primates treated with antiviral drugs, researchers have concluded.

16 Mar 2020

Researchers develop new kind of CRISPR screen technology to target RNA

CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases.

16 Mar 2020

Potential breakthrough in cancer immunotherapy with gasdermin E

A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present.

11 Mar 2020

Gut bacteria can accumulate in tumors and improve effectiveness of cancer immunotherapy

Researchers at the University of Texas Southwestern Medical Center and University of Chicago have discovered that bacteria that usually live in the gut can accumulate in tumors and improve the effectiveness of immunotherapy in mice.

10 Mar 2020

A previously unknown mechanism could be new therapeutic target for cancer immunotherapy

Researchers at UC have discovered a previously unknown mechanism that could explain the reason behind decreased immune function in cancer patients and could be a new therapeutic target for immunotherapy for those with head and neck cancers.

10 Mar 2020

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor?

7 Mar 2020

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences, Dana-Farber Cancer Institute, and Harvard's Department of Stem Cell and Regenerative Biology, announce the formation of a new NIH-funded Immuno-Engineering to Improve Immunotherapy Center.

7 Mar 2020

Blocking immune T-cell regulator may help boost tumor killing, study shows

Immune system T-cells are more able to destroy skin cancer cells when a T-cell regulator called SLAMF6 is missing, a new study in eLife shows.

3 Mar 2020

New drug could help significantly improve success rate of cancer immunotherapy

A study led by the University of Southampton, funded by Cancer Research UK, has shown a new drug - originally developed to tackle the scarring of organ tissue - could help to significantly improve the success rate of cancer immunotherapy treatment.

2 Mar 2020

Discovery may open up new avenues into improving cancer immunotherapy

New cancer immunotherapy approaches are revolutionizing treatment options for breast cancer patients. However, many lead to insufficient immune responses rendering the therapies incapable of completely eradicating tumors.

23 Feb 2020

Using newly discovered immune cell type to fight pancreatic cancer

Immunotherapy is showing great promise for treating cancer. But so far, this approach has been effective in only about 20% of all cancers. To advance those results, researchers are looking for new ways to mobilize the immune system to destroy tumors.

23 Feb 2020

Bioengineers create light-controllable CAR T cells for cancer immunotherapy

Bioengineers at the University of California San Diego have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer.

19 Feb 2020

Targeting regulatory T cells could boost the effects of cancer immunotherapy

A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor.

17 Feb 2020

Universal 'One-Size-Fits-All' Cancer Treatment

Andrew Sewell speaks to News-Medical about his breakthrough research, in which he has discovered a new T-Cell that could treat most cancers.

14 Feb 2020

Researchers engineer probiotics to safely deliver immunotherapies to tumors

Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors.

12 Feb 2020

Powerful vaccine could boost the effectiveness of cancer immunotherapy

Supercharging the mutation rate in cancer cells can create a powerful vaccine that is able to boost the effectiveness of immunotherapy, a major new study reports.

9 Feb 2020

Avacta demonstrates initial proof-of-concept for TMAC drug conjugates in pre-clinical study

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that it has demonstrated initial proof-of-concept for its proprietary new class of drug conjugate, TMAC, in a pre-clinical animal model of cancer.

From Avacta Life Sciences Ltd. 28 Jan 2020