Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Female reproductive hormones may be protective against COVID-19

In an article recently published in Trends in Endocrinology & Metabolism, Graziano Pinna from the University of Illinois in Chicago outlines some of the evidence suggesting that female reproductive hormones may play a role in the sex bias that has been observed in coronavirus disease 2019 (COVID-19).

29 Nov 2020

Normal sleep depends on bacteria in the gut

With fall and winter holidays coming up, many will be pondering the relationship between food and sleep.

27 Nov 2020

Researchers discover new way for early detection of shade avoidance syndrome in plants

Researchers from the Disruptive & Sustainable Technologies for Agricultural Precision Interdisciplinary Research Group of Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore and Temasek Life Sciences Laboratory have discovered a way to use Raman spectroscopy for early detection of shade avoidance syndrome in plants.

25 Nov 2020

Sex steroids may play a protective role in COVID-19, shows study

A new paper from a UIC researcher shows evidence that suggests sex steroids may play a role in protecting against COVID-19 symptoms.

24 Nov 2020

Study shows link between COPD and the gut microbiome

Research led by the Centenary Institute, the University of Technology Sydney and the University of Queensland has shown for the first time a link between chronic obstructive pulmonary disease (COPD), an often fatal lung condition, and the gut microbiome.

19 Nov 2020

Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

Short bursts of exercise elicit widespread changes in the body's levels of metabolites

Short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health, a study by Massachusetts General Hospital has found.

16 Nov 2020

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Itraconazole is a broad-spectrum antifungal agent that has been shown to have some in vitro activity against SARS-CoV-2 by a team of Belgian and German researchers.

16 Nov 2020

MTT procedure improves gastrointestinal, behavioral symptoms in ASD children

According to the Centers for Disease Research, 1 in 54 children is diagnosed with autism spectrum disorder (ASD) each year, and the number has been rising.

15 Nov 2020

COVID-19-associated pulmonary aspergillosis caused by aspergillus fumigatus

A new study published on the preprint server bioRxiv in November 2020 discusses the characteristics of COVID-19 associated pulmonary aspergillosis (CAPA).

10 Nov 2020

Preeclampsia-related placental gene expression may be associated with vitamin D status

According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies. It can cause serious, sometimes fatal, complications in the mother and child.

10 Nov 2020

UH professor is developing a Chinese herbal medicine formula to improve cancer therapy

University of Houston professor of pharmaceutics Ming Hu is developing and testing an ancient Chinese herbal medicine formula, first described in 280 A.D., to improve cancer therapy.

4 Nov 2020

Remdesivir metabolite GS-441524 inhibits SARS CoV-2 in mouse model, finds study

This new study titled, "Remdesivir Metabolite GS-441524 Efficiently Inhibits SARS-CoV-2 Infection in Mouse Model," was released online as a preprint on the bioRxiv* server, prior to undergoing the peer-review process.

2 Nov 2020

5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro

Researchers tested 5-amino levulinic acid in vitro in human-derived cells and found it prevents severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Because it is safe and ubiquitous in plants and animals, it could be a potential drug against SARS-CoV-2.

1 Nov 2020

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

University of Illinois Urbana-Champaign Professor of Molecular and Integrative Physiology Erik Nelson has won a $4.5M Era of Hope Scholar Award from the United States Department of Defense (DoD) Breast Cancer Research Program (BCRP).

30 Oct 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin - NMR, EPR and Imaging 30 Oct 2020

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

27 Oct 2020

Dietary 1H-NMR “Fingerprints” Could Help Fight Against Chronic Disease

Metabolic urine profiling could provide an approach to understand what people have been eating, without them needing to tell you. Here, researchers from Imperial College London, Prof Gary Frost, Prof Elaine Holmes, and Dr. Isabel Garcia-Perez, explain why this could be invaluable to both nutritional research and individuals.

From Bruker BioSpin - NMR, EPR and Imaging 27 Oct 2020

Metabolite of dietary soy may lower risk factor for dementia

A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia--with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health.

22 Oct 2020

NMR Metabolomics as Novel Screening Tool for New-borns (For Research Only)

In this interview, Oscar Millet, group leader of the Precision Medicine and Metabolism group of the CIC bioGUNE, talked to News Medical about his research into the use of nuclear magnetic resonance spectroscopy (NMR) metabolomic analysis as a clinical screening tool. His team has used NMR to screen urine samples form new-borns for congenital metabolic disorders.

From Bruker BioSpin - NMR, EPR and Imaging 20 Oct 2020