Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

An abundance of biomolecules linked to COVID-19 status and severity

Tapping into the potential of the multi-omic method to uncover functional connections between various classes of biomolecules, researchers from notable institutions in the United States have discovered sets of co-varying molecules that shed light on coronavirus disease (COVID-19) pathophysiology and provide treatment opportunities.

20 Jul 2020

Experimental therapy slows zika replication and prevents microcephaly in mice

An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation, enables the immune system to combat replication of zika virus in the organism far more effectively.

20 Jul 2020

Aspirin and flavonoids in fruits and vegetables could help prevent colorectal cancer

A diet rich in fruits and vegetables and a daily dose of aspirin have one thing in common-;both can help prevent colorectal cancer. Yet scientists have struggled for decades to find the source of their ability to inhibit cancer cell growth.

7 Jul 2020

Repurposed drug for acute lung injury in COVID-19

Now, a new study addresses the possible use of an FDA-approved monoclonal antibody, called fostamatinib, a spleen tyrosine kinase inhibitor (SYK), to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respiratory distress syndrome (ARDS). People who have severe COVID-19 disease may develop ARDS.

2 Jul 2020

Stool microbial and metabolite signatures predict cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to cirrhosis, liver cancer, liver failure and death.

30 Jun 2020

Researchers show how upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

New, five-minute urine test measures the health of a person's diet

Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'.

22 Jun 2020

Study identifies a previously unknown mechanism that contributes to intestinal cancer

A MedUni Vienna study group has identified a previously unknown mechanism involved in the development of intestinal cancer: The bacterial microbiome activates the so-called immune checkpoint Ido1 in Paneth cells, a special cell that is only found in the gastrointestinal tract, thereby preventing local intestinal inflammation.

18 Jun 2020

High-salt diet may modulate the gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

9 Jun 2020

Drug offers hope for patients with primary hyperoxaluria type 1

Primary hyperoxaluria type 1 (PH1) is an autosomal recessive inherited disorder that begins in childhood and adolescence.

8 Jun 2020

New insights into how parenteral oil emulsions prevent liver disease in preterm babies

Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients.

4 Jun 2020

Cognitive aptitudes of young women may be more affected with high alcohol use than men

Female college students appear to be more affected by high alcohol use than men, which may lead to less interest in academics, according to new research including by faculty at Binghamton University, State University of New York.

1 Jun 2020

High-throughput analysis of blood plasma could help identify biomarkers for ALS

High-throughput analysis of blood plasma could aid in identification of diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis (ALS), according to research from North Carolina State University.

29 May 2020

New technology developed to map cholesterol metabolism in the brain

A team of researchers led by Swansea University have developed new technology to monitor cholesterol in brain tissue which could uncover its relation to neurodegenerative disease and pave the way for the development of new treatments.

29 May 2020

Researchers identify risk factors for fatty liver disease

Researchers at Massachusetts General Hospital have uncovered an unexpected connection between an imbalance of electrons in liver cells and many metabolic problems that increase the risk for conditions such as cardiovascular disease and fatty liver disease.

29 May 2020

New Orbitrap Exploris 120 mass spectrometer redefines productivity in small molecule applications

Scientists working across small molecule applications require systems that support extensive, in-depth analysis of multiple complex samples, while simultaneously increasing output and decreasing costs.

From Thermo Fisher Scientific Inc. 28 May 2020

Simple urine-testing method for people with kidney stones offers results in 30 minutes

An improved urine-testing system for people suffering from kidney stones inspired by nature and proposed by researchers from Penn State and Stanford University may enable patients to receive results within 30 minutes instead of the current turnaround time of a week or more.

27 May 2020

Metabolite News and Research

Further Reading

An abundance of biomolecules linked to COVID-19 status and severity

Experimental therapy slows zika replication and prevents microcephaly in mice

Aspirin and flavonoids in fruits and vegetables could help prevent colorectal cancer

Repurposed drug for acute lung injury in COVID-19

Stool microbial and metabolite signatures predict cirrhosis

Researchers show how upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

New, five-minute urine test measures the health of a person's diet

Study identifies a previously unknown mechanism that contributes to intestinal cancer

High-salt diet may modulate the gut microbiome

Drug offers hope for patients with primary hyperoxaluria type 1

New insights into how parenteral oil emulsions prevent liver disease in preterm babies

Cognitive aptitudes of young women may be more affected with high alcohol use than men

High-throughput analysis of blood plasma could help identify biomarkers for ALS

New technology developed to map cholesterol metabolism in the brain

Researchers identify risk factors for fatty liver disease

New Orbitrap Exploris 120 mass spectrometer redefines productivity in small molecule applications

Simple urine-testing method for people with kidney stones offers results in 30 minutes

Environmental chemicals linked to changes in the gut microbiome and health

Transcranial direct current stimulation does not affect metabolism, study shows

Novel approach could lead to more targeted search for new medicinal plants

Pioneering Live Cell Imaging - Yokogawa's Impact and Innovations

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Latest Life Science News