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Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

Researchers recently investigated the effect of infection with SARS-CoV-2 in patients with hematologic malignancies in minority populations.

21 Sep 2021

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

The scientists assessed epidemiological data from March to December 2020 from the CDC to investigate the prevalence of COVID-19 disease among different age groups.

21 Sep 2021

Study outlines a baseline bundle of care interventions for critically ill patients

Critical illness results in millions of deaths globally every year, many of which could be avoided with basic, life-saving care. Now, a new study led by researchers at Karolinska Institutet in Sweden outlines a baseline bundle of care interventions that global experts agree should be available for all critically ill patients. The study, published in the journal BMJ Global Health, provides a blueprint for hospitals on how to reduce preventable deaths, including from COVID-19.

21 Sep 2021

Could monitoring headaches after COVID-19 vaccination help identify rare cases of cerebral venous thrombosis?

Researchers from the Akershus University Hospital in Norway investigated 77 cases of CVT in vaccinated subjects to identify risks and warning signs to better predict these severe side effects.

21 Sep 2021

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

An opinion article aims to provide evidence that SP could be the possible factor for initiating the cytokine storm during severe SARS-CoV-2 infection.

21 Sep 2021

Study to examine psychosocial factors associated with CVD risk among urban African American adults

The Biopsychosocial Health lab from Wayne State University has been awarded $3,590,488 from the National Heart, Lung and Blood Institute of the National Institutes of Health to conduct a project titled "Stress and Cardiovascular Risk Among Urban African American adults: A Multilevel, Mixed Methods Approach."

21 Sep 2021

Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice

In a recently published article on the bioRxiv* preprint server, scientists from the USA and UK have described the significance of early inflammatory signaling pathways in determining the severity of coronavirus disease 2019 (COVID-19).

21 Sep 2021

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Researchers from Europe recently demonstrated altered levels of factor XII (FXII) and its activation products in 2 independent cohorts of critically ill patients with COVID-19 compared to patients suffering from severe acute respiratory distress syndrome caused by the influenza virus (acute respiratory distress syndrome (ARDS)-influenza).

21 Sep 2021

Increasing physical activity, fitness may be superior to weight loss for reducing health risks

The prevalence of obesity around the world has tripled over the past 40 years, and, along with that rise, dieting and attempts to lose weight also have soared. But according to a review article publishing September 20 in the journal iScience, when it comes to getting healthy and reducing mortality risk, increasing physical activity and improving fitness appear to be superior to weight loss. The authors say that employing a weight-neutral approach to the treatment of obesity-related health conditions also reduces the health risks associated with yo-yo dieting.

21 Sep 2021

COVID-19 vaccine effectiveness against SARS-CoV-2 variants

A commentary published in the journal Cell summarizes international data on vaccine effectiveness against new severe acute respiratory coronavirus 2 (SARS-CoV-2) variants. Evidence shows that the currently approved vaccines continue to be effective in preventing severe and symptomatic illness — even with the widely circulating Delta variant.

21 Sep 2021

Researchers identify prediction markers which can be used to define COVID-19 severity

An estimated 14−17% of hospitalized COVID-19 patients develop a severe form of the disease, requiring oxygen support and admission to the intensive care unit.

20 Sep 2021

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Researchers complete an extensive search on previously published studies to understand the efficacy of convalescent plasma in treating COVID-19.

20 Sep 2021

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Systematic review focuses on women's health associated with menopausal hormone therapy

Treatment with estrogen in menopause is both good and bad for women's health. The picture is complex and the scientific evidence sometimes scanty or only moderately solid, a study shows. University of Gothenburg researchers took part.

20 Sep 2021

New data shows benefit of drug combination for metastatic castration resistant prostate cancer

New findings by researchers at Yale Cancer Center show the drug combination of nivolumab and rucaparib shows clinical activity for patients with chemotherapy-naïve, metastatic castration resistant prostate cancer (mCRPC).

18 Sep 2021

Novel drug combinations improve progression-free survival for patients with advanced NSCLC

New findings from a large study led by researchers at Yale Cancer Center shows the addition of the drugs oleclumab or monalizumab to durvalumab improved progression-free survival for patients with locally advanced non-small cell lung cancer (NSCLC).

18 Sep 2021

Changing weather patterns in Laos linked to increase in typhus cases

Changing weather patterns in Laos may be responsible for an increase in bugs responsible for the neglected tropical diseases scrub typhus and murine typhus, a new study finds.

18 Sep 2021

What pushed Israel out of herd immunity?

Scientists have recently tried to explain the factors that could be responsible for the recent outbreaks of COVID-19 in Israel.

17 Sep 2021

Humoral and cellular response to COVID-19 vaccines in patients with IBD

A new study published in the preprint server medRxiv* aimed to evaluate the humoral and cellular response to COVID-19 vaccine in patients with IBD undergoing biologic or immunomodulatory therapy.

17 Sep 2021

Study points to a possible new approach for treating MRSA superbug

A study released in STEM CELLS Translational Medicine, by researchers at the Baker Institute for Animal Health, part of Cornell University's College of Veterinary Medicine, Ithaca, N.Y., details in a relevant ex vivo model how treating wounds with the secretion of a type of stem cell called mesenchymal stromal cell (MSC) effectively reduced methicillin-resistant Staphylococcus aureus – better known as MRSA viability and stimulated the surrounding skin cells to build up a defense against the bacterial invader.

16 Sep 2021

Mortality News and Research

Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

Study outlines a baseline bundle of care interventions for critically ill patients

Could monitoring headaches after COVID-19 vaccination help identify rare cases of cerebral venous thrombosis?

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

Study to examine psychosocial factors associated with CVD risk among urban African American adults

Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Increasing physical activity, fitness may be superior to weight loss for reducing health risks

COVID-19 vaccine effectiveness against SARS-CoV-2 variants

Researchers identify prediction markers which can be used to define COVID-19 severity

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Two proteins work in tandem to build lifelines to cancer cells, study finds

Systematic review focuses on women's health associated with menopausal hormone therapy

New data shows benefit of drug combination for metastatic castration resistant prostate cancer

Novel drug combinations improve progression-free survival for patients with advanced NSCLC

Changing weather patterns in Laos linked to increase in typhus cases

What pushed Israel out of herd immunity?

Humoral and cellular response to COVID-19 vaccines in patients with IBD

Study points to a possible new approach for treating MRSA superbug

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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