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Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Pulmonary dysfunction in pediatric patients after acute COVID-19 infection

A recent study examined the pulmonary dysfunction persistent in pediatric populations post-acute COVID-19 infection.

24 Feb 2022

Immunological landscape of England during Omicron-driven SARS-CoV-2 wave

In a new study, researchers determined the immunological landscape of England throughout the SARS-CoV-2 Omicron wave.

24 Feb 2022

Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

A new study posted to the bioRxiv* preprint server reports on the development of anti-RBD immunoglobulin Y (IgY) antibodies from chicken eggs to block the binding of the viral RBD to human ACE2 receptors. This approach has several advantages since chicken egg-derived IgY can be edible and polyclonal can target multiple epitopes, enhancing neutralizing activity.

23 Feb 2022

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is hurting our loved ones — even those that walk on four legs. Researchers from the University of Pennsylvania documented the recovery of an 11-year old indoor housecat living in Delaware who first presented to the veterinary hospital after experiencing distressing gastrointestinal symptoms.

23 Feb 2022

Study on Omicron related mortality in cancer patients during recent COVID wave

A recent pre-proof study published in the journal Cancer Cell assessed the CFR of cancer patients during the third wave of the coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 Omicron variant.

23 Feb 2022

Study explores the effectiveness of Moderna COVID-19 vaccine against omicron, delta variants

New Kaiser Permanente research published February 21, 2022 in Nature Medicine shows that while Moderna COVID-19 vaccine protection is strong against coronavirus infection by the delta variant, it is not as strong against infection from the omicron variant.

23 Feb 2022

White blood cell count as a prognostic indicator of COVID-19

Based on a new study, researchers concluded WBC count variations worsen clinical outcomes such as severity, mortality, and hospital discharge rates leading to a poorer prognosis in COVID-19 patients.

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Understanding the immune responses after secondary vaccinations with Pfizer and Moderna vaccines

In a new study, researchers assessed the serological responses to secondary booster doses of Pfizer's Comirnaty and Moderna's Spikevax COVID-19 vaccines.

23 Feb 2022

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

A recent study reported the abrogation of inhibition of the NK cells by a SARS-CoV-2-encoded protein presented by HLA-E.

23 Feb 2022

Study explores the impact of COVID-19 on pancreatic cells

New study findings showed that SARS-CoV-2 caused a productive yet restricted infection of pancreatic islet cells and an insignificant inflammatory response.

23 Feb 2022

Cardiopulmonary limitations six months after surviving COVID-19

A recent prospective cohort study assessed the cardiopulmonary effects in patients six months after COVID-19 infection.

23 Feb 2022

Outcomes of phase 3 clinical trial of CVO PLUS CURATIF capsules for COVID-19 treatment

A phase 3 randomized clinical trial has recently been conducted to investigate the efficacy of a capsule formulation in treating mild-to-moderate COVID-19 patients.

23 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

SARS-Cov-2 reinfection in Syrian hamsters does not result in disease

Researchers have been investigating the reinfection of different SARS-CoV-2 variants in Syrian hamsters and found that this does not seem to result in disease or any significant pulmonary pathology.

23 Feb 2022

High nasopharyngeal viral load in SARS-CoV-2 Omicron-induced infection

In a recent study posted to the Research Square* pre-print server, a team of researchers from Italy and the United States (US) retrospectively reviewed and compared viral load in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron and previous SARS-CoV-2 strain-induced infection.

23 Feb 2022

More evidence vaccines prevent ICU admission and mortality from SARS-CoV-2

In a recent study posted to the medRxiv* preprint server, researchers estimated the comparative virulence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) between the vaccinated and unvaccinated subjects hospitalized with coronavirus disease 2019 (COVID-19) in Canada.

23 Feb 2022

Closing bars and restaurants does not appear to have suppressed COVID-19 in Japan

In a recent study posted in the Research Square* preprint server, which is under consideration at the journal Scientific Reports, a team of researchers conducted a longitudinal survey in 11 Japanese prefectures to evaluate whether early closure of full-service restaurants and bars reduced the incidence and symptoms of coronavirus disease 2019 (COVID-19) during February 2021.

23 Feb 2022

SARS News and Research

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Pulmonary dysfunction in pediatric patients after acute COVID-19 infection

Immunological landscape of England during Omicron-driven SARS-CoV-2 wave

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Study on Omicron related mortality in cancer patients during recent COVID wave

Study explores the effectiveness of Moderna COVID-19 vaccine against omicron, delta variants

White blood cell count as a prognostic indicator of COVID-19

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Understanding the immune responses after secondary vaccinations with Pfizer and Moderna vaccines

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

Study explores the impact of COVID-19 on pancreatic cells

Cardiopulmonary limitations six months after surviving COVID-19

Outcomes of phase 3 clinical trial of CVO PLUS CURATIF capsules for COVID-19 treatment

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

SARS-Cov-2 reinfection in Syrian hamsters does not result in disease

High nasopharyngeal viral load in SARS-CoV-2 Omicron-induced infection

More evidence vaccines prevent ICU admission and mortality from SARS-CoV-2

Closing bars and restaurants does not appear to have suppressed COVID-19 in Japan

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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