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SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

A new study discusses the activation of the complement system to determine its role in COVID-19-related deaths.

17 Jan 2022

Evidence that monoclonal antibodies can reduce COVID-19 (Delta) mortality

Researchers prevent evidence on the efficacy of neutralizing monoclonal antibodies in treating COVID-19.

17 Jan 2022

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Researchers determine the driving factors for disease severity and death due to COVID-19.

17 Jan 2022

South African study confirms SARS-CoV-2 Omicron less severe than Delta even for unvaccinated

Researchers compare the outcomes of the fourth and previous waves of the COVID-19 pandemic in South Africa.

17 Jan 2022

Sniffer dogs detect long COVID after 1.5 years

Researchers used sniffer dogs to test the presence of SARS-CoV-2 infection in axillary sweat samples of long COVID-19 patients.

17 Jan 2022

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Researchers investigate the efficacy of hydroxychloroquine and chloroquine in the treatment of patients hospitalized with COVID-19.

17 Jan 2022

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

New research assesses the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation in response to SARS-CoV-2 and its spike protein, and the effects of this exposure in the presence of a-synuclein protein aggregate fibrils.

17 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Quantification of SARS-CoV-2 variants in wastewater samples

In a new study, a team of researchers introduced a novel method to estimate the proportion of different SARS-CoV-2 strains in wastewater samples.

17 Jan 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Seroepidemiologic surveys for assessment of the COVID-19 pandemic in Japan

In a new study, a team of researchers demonstrated that Japan had witnessed a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant-induced endemic between August and December 2021.

17 Jan 2022

Framework for understanding cross-country spread of COVID-19 in the context of the globally interconnected economy

A study published in Scientific Reports uses a three-dimensional conceptual model to examine COVID-19's global spatiotemporal dissemination.

17 Jan 2022

Researchers construct models to predict SARS-CoV-2 mutable and constrained positions

In a study published in PNAS, researchers have attempted to create a model that can successfully predict which positions are likely to mutate in the future.

17 Jan 2022

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

In a new study, researchers used a simple phenomenological model to investigate the role of immunocompromised hosts in SARS-CoV-2 antigenic development.

17 Jan 2022

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Researchers have been investigating the Omicron epidemic in Japan and have recently released an early report on the infectious period of the disease.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Study reveals aerosol transmission of SARS-CoV-2 via floor drains

A new study investigated COVID-19 cases in an apartment complex in South Korea and explored the possibility of aerosol transmission without direct contact between infected individuals with the help of molecular phylogenetic analysis and epidemiological surveillance.

17 Jan 2022

Nine-month survey of COVID-19 vaccine effectiveness in North Carolina

A new paper reports increased breakthrough infections with SARS-CoV-2, the agent behind the ongoing COVID-19 pandemic.

17 Jan 2022

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

A new paper published in the journal JCI Insight reports on the differential levels of immunity achieved in those with and without a history of prior infection with the virus following one and two doses of the earliest vaccines to be approved for emergency use.

17 Jan 2022

Syndrome News and Research

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

Evidence that monoclonal antibodies can reduce COVID-19 (Delta) mortality

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

South African study confirms SARS-CoV-2 Omicron less severe than Delta even for unvaccinated

Sniffer dogs detect long COVID after 1.5 years

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

Quantification of SARS-CoV-2 variants in wastewater samples

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

Seroepidemiologic surveys for assessment of the COVID-19 pandemic in Japan

Framework for understanding cross-country spread of COVID-19 in the context of the globally interconnected economy

Researchers construct models to predict SARS-CoV-2 mutable and constrained positions

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Study reveals aerosol transmission of SARS-CoV-2 via floor drains

Nine-month survey of COVID-19 vaccine effectiveness in North Carolina

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

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