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A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Researchers compared the immunogenicity of the reduced and standard doses of the BNT162b2 and mRNA-1273 vaccine in adults immunized with two doses of the CoronaVac vaccine.

8 Mar 2022

World's largest genetic study reveals fresh details about severe Covid-19

The world's largest study of the genetics of critical Covid-19, involving more than 57,000 people, has revealed fresh details about some of the biological mechanisms behind the severe form of the disease.

7 Mar 2022

Study explores differentially expressed immune genes for COVID-19 patient stratification

In a new study, researchers determined the transcriptional signatures associated with the severity of COVID-19.

7 Mar 2022

Current progress in SARS-CoV-2 vaccine candidates

In a new study, researchers illustrated the current progress and obstacles in COVID-19 vaccine development.

7 Mar 2022

Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

An new study reports that a third dose of the Pfizer BNT162b2 vaccine produces high levels of anti-spike IgG antibodies in kidney transplant recipients.

6 Mar 2022

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Researchers develop an Omicron variant mRNA vaccine that is be more potent in generating nAbs as compared to other available vaccines.

6 Mar 2022

T-cell cytokine and fatty acid work together to trigger a type of cell death

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

4 Mar 2022

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

In a new study, researchers presented the Multiscale potential of heat-diffusion for affinity-based trajectory embedding approach that identified multimodal signatures of SARS-CoV-2shut.

3 Mar 2022

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

A recent study analyzes IFNa subtypes for their therapeutic potential against SARS-CoV-2 and identified the underlying immune signatures and mechanisms.

3 Mar 2022

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

A recent study provides a better understanding of whether SARS-CoV-2 infection is linked with the occurrence of chilblains.

3 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

In a new study, researchers evaluated the immune responses induced by the mRNA-based SARS-CoV-2 vaccination against SARS-CoV-2 variants in multiple myeloma patients.

1 Mar 2022

Study reveals how the immune system can be triggered to attack cancer cells

New research from the University of East Anglia and Quadram Institute reveals how our immune system can be triggered to attack cancer cells.

1 Mar 2022

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

A recent study observed that peptide-based vaccination against SARS-CoV-2 failed to protect mice against COVID-19, albeit eliciting T cell responses.

28 Feb 2022

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

In a new study published in ACS Infectious Diseases journal, scientists biochemically and structurally evaluated the PLpro from a subgroup 2b bat coronavirus, BtSCoV-Rf1.2004, to identify unique structural features or enzymatic biases of the subgroup 2b.

28 Feb 2022

Interferon News and Research

A promising approach for COVID-19 prophylaxis

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

World's largest genetic study reveals fresh details about severe Covid-19

Study explores differentially expressed immune genes for COVID-19 patient stratification

Current progress in SARS-CoV-2 vaccine candidates

Combating COVID cytokine storm with targeted nucleic acid therapies

CD4 T-cell immunity active six months into COVID-19 convalescence

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

T-cell cytokine and fatty acid work together to trigger a type of cell death

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

Study reveals how the immune system can be triggered to attack cancer cells

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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