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A cytokine pattern that predicts adverse outcomes in COVID-19

A new study published on the preprint server medRxiv in May 2020 reports the discovery of a predictive pattern of cytokines in COVID-19 infection that could guide clinical management if validated.

2 Jun 2020

Academic emergency departments provide unconditional care to COVID-19 patients

"Academic emergency departments never deny emergency care to any person." That is the statement put forth in a commentary from the Board of Directors of the Society for Academic Emergency Medicine and the Senior Editorial Board of Academic Emergency Medicine journal.

2 Jun 2020

Oral antidiabetics improve outcomes in diabetics with colorectal cancer

Bottom Line: Among patients with both colorectal cancer and diabetes in Korea, those who had a high adherence to their oral diabetes medication had a significantly reduced risk of overall mortality compared with those with lower adherence.

1 Jun 2020

Deep vein clots in critical COVID-19 illness

A new research paper published in the journal JAMA Network Open in May 2020 reports a high incidence of deep vein clots in patients with severe COVID-19 at a single French medical center. This could indicate the need for systematic anticoagulant therapy in these patients as a preventive measure.

31 May 2020

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

A new meta-analysis published on the preprint server medRxiv by the researchers from the United States and Greece reveals that the likelihood of death is 65% higher in hospitalized coronavirus disease (COVID-19) patients with diabetes when compared to non-diabetics – urging the adequate glucose control in the era of the pandemic.

31 May 2020

Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

A harmonization of 'big data' in examining long-term outcomes with contemporary treatment for pediatric and adult Hodgkin lymphoma patients is yielding a new approach to inform future clinical trial design and enhance clinical decision-making.

30 May 2020

Identifying optimal vasopressor treatment for nontraumatic subarachnoid hemorrhage

Results of an Electronic Health Record (EHR) study assessing the most commonly used medications for raising blood pressure in patients with nontraumatic subarachnoid hemorrhage (SAH), a rare type of stroke, have been published in Neurosurgical Focus by scientists at The University of Texas Health Science Center at Houston (UTHealth).

30 May 2020

Clinical trial shows anti-tumor responses in metastatic castration-resistant prostate cancer patients

The preliminary results of a Phase I clinical trial conducted by researchers at the Yale Cancer Center have shown that ARV-110, an androgen receptor PROTAC protein degrader, demonstrates clinical evidence of anti-tumor responses in patients with metastatic castration-resistant prostate cancer (mCRPC) who have failed prior therapy.

29 May 2020

Survival probabilities in esophageal surgery increase with volume of hospital services

In complex surgery, is there a correlation between the volume of services provided per hospital and the quality of treatment results? This is the question addressed in eight commissions on minimum volumes that the Federal Joint Committee (G-BA) awarded to the Institute for Quality and Efficiency in Health Care.

29 May 2020

Study: Glucocorticoids are harmful for patients suffering from viral respiratory infections

Glucocorticoids are widely used in treating acute respiratory distress syndrome (ARDS) despite there being no indisputable scientific evidence of their effectiveness.

29 May 2020

Researchers investigate possible causes of high COVID-19 mortality in Italy

On March 11th, 2020 the World Health Organization declared Coronavirus disease (COVID-19) a pandemic.

29 May 2020

Targeted therapy shows immense benefit for patients with early stage NSCLC

According to findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery significantly improves disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC) with EGFR gene mutations.

29 May 2020

Cardiac surgery stalled as novel coronavirus spread

As the novel coronavirus spread across the globe in early 2020, hospitals worldwide scaled back medical procedures, including life-saving heart surgery, to deal with the emerging threat of COVID-19.

28 May 2020

Women and minorities inadequately represented in clinical trials for novel cardiometabolic drugs

Women and minorities, particularly African Americans, continue to be inadequately represented in clinical trials for novel cardiometabolic medications, with no evidence of improvement in enrollment numbers over the past decade, according to new research published last week in the Journal of the American Heart Association, an open-access journal of the American Heart Association.

28 May 2020

Canadian study of COVID-19 patients admitted to ICUs finds lower overall mortality

A Canadian case series of all patients with COVID-19 admitted to six intensive care units (ICUs) in Metro Vancouver found patient outcomes were substantially better than reported in other jurisdictions. The paper is published in CMAJ.

27 May 2020

Is air pollution a risk factor for COVID-19 infection?

The COVID-19 pandemic began at the very end of 2019 in Wuhan city, Hubei province, China. However, its spread soon began to threaten the health of the whole country and then of the world, leading to nearly 5.7 million cases and over 355,000 dead as of today. A new study, published on the preprint server medRxiv* in May 2020, explores the effects of air pollution on COVID-19 infections in China.

27 May 2020

Research provides guidance for treating pancreatic cancer patients during COVID-19 pandemic

The novel coronavirus (COVID-19) pandemic not only affects patients who have the virus, but strikes the entire healthcare system including the care for patients with cancer.

27 May 2020

Is vitamin D really linked to excess COVID-19 mortality?

The ongoing COVID-19 pandemic has caused many deaths, numbering in the hundreds of thousands, over many different countries. However, the reasons for the differential mortality from region to region are far from clear, despite intensive research.

27 May 2020

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

A recent paper by researchers from China demonstrated comparable expression levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry mediators in adults and children, suggesting that previously implied difference in viral-entry associated genes is likely not responsible for milder symptoms in children. The study is currently available on the medRxiv preprint server.

27 May 2020

Neurological complications of COVID-19: What is known so far?

Researchers at the São Leopoldo Mandic School of Medicine in Brazil have presented a review of the current data available on the neurological effects of coronavirus disease 2019 (COVID-9).

27 May 2020

Mortality News and Research

A cytokine pattern that predicts adverse outcomes in COVID-19

Academic emergency departments provide unconditional care to COVID-19 patients

Oral antidiabetics improve outcomes in diabetics with colorectal cancer

Deep vein clots in critical COVID-19 illness

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

Identifying optimal vasopressor treatment for nontraumatic subarachnoid hemorrhage

Clinical trial shows anti-tumor responses in metastatic castration-resistant prostate cancer patients

Survival probabilities in esophageal surgery increase with volume of hospital services

Study: Glucocorticoids are harmful for patients suffering from viral respiratory infections

Researchers investigate possible causes of high COVID-19 mortality in Italy

Targeted therapy shows immense benefit for patients with early stage NSCLC

Cardiac surgery stalled as novel coronavirus spread

Women and minorities inadequately represented in clinical trials for novel cardiometabolic drugs

Canadian study of COVID-19 patients admitted to ICUs finds lower overall mortality

Is air pollution a risk factor for COVID-19 infection?

Research provides guidance for treating pancreatic cancer patients during COVID-19 pandemic

Is vitamin D really linked to excess COVID-19 mortality?

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

Neurological complications of COVID-19: What is known so far?

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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