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A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

Scientists at Washington University School of Medicine in St. Louis have developed a compound that prevents SARS-CoV-2 and related coronaviruses from entering cells.

11 Oct 2021

Delta SARS-CoV-2 variant does not make kids sicker than Alpha, study finds

Children are not at risk for more severe COVID-19 disease with Delta compared to earlier severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, finds a new medRxiv* preprint study. In the first large-scale epidemiological study comparing SARS-CoV-2 infection between variants in children, researchers found children were more likely to be as sick from Delta as they would be if they were infected with the Alpha variant.

11 Oct 2021

Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA

A recent study compares the transmissibility of the SARS-CoV-2 Alpha and Delta variants in six states across New England in the United States

11 Oct 2021

Higher COVID-19 hospitalization and mortality rates reported in rural America

A recent study discusses variations in the hospitalization and mortality rates due to SARS-CoV-2 infection among rural and urban regions in the U.S.

11 Oct 2021

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

A recent study demonstrates that antibodies generated in response to mRNA-based COVID-19 vaccination target more epitopes across the spike protein.

11 Oct 2021

An investigation of SARS-CoV-2 infection in diabetic pregnancies

Researchers discuss the basic and clinical science of the potential inter-relationships between diabetes mellitus and COVID-19 in pregnancies.

11 Oct 2021

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

A new study assesses antibody and functional T-cell responses at 6 months after complete vaccination with the Pfizer-BioNTech vaccine.

11 Oct 2021

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

A new study finds that plasmonic sensing of LAMP amplicons through DNA hybridization enables highly specific detection of SARS-CoV-2 RNA.

11 Oct 2021

COVID-19 aerosol transmission simulation-based risk analysis for in-person learning

Researchers develop a simulation model to characterize the risks and uncertainties associated with infections from aerosol exposure during in-person classes.

11 Oct 2021

A simple method to predict future COVID-19 hospitalization

A simple model with the ability to forecast probable COVID-19 hospitalization numbers in the short term is described, requiring less input information and generating more accurate predictions than other models.

11 Oct 2021

Researchers discover molecules in the blood that can indicate impending dementia

Researchers at the DZNE and the University Medical Center Göttingen (UMG) have identified molecules in the blood that can indicate impending dementia. Their findings, which are presented in the scientific journal "EMBO Molecular Medicine", are based on human studies and laboratory experiments. Various university hospitals across Germany were also involved in the investigations.

11 Oct 2021

The role of inhibiting palmitoylation of the SARS-CoV-2 spike protein on viral infectivity

It is demonstrated that palmitoylation of the first five cysteine residues of the C-terminal domain of the SARS-CoV-2 spike protein facilitates cell entry and the formation of syncytia.

11 Oct 2021

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Researchers addressed the question of using reporter particles pseudotyped with the S protein of SARS-CoV-2, which are suitable tools to examine SARS-CoV-2 neutralization antibodies.

11 Oct 2021

Prior immunity to influenza, not SARS-CoV-2, prevents severe disease and mortality

Researchers from the Israel Institute of Biological Research delineated the interplay between IAV and SARS CoV-2 infections.

11 Oct 2021

Vaccine-induced memory B cells can recognize SARS-CoV-2 variants

Researchers have been investigating the effect that memory B cells produced in individuals who have received an mRNA vaccine have against SARS-CoV-2 variants.

11 Oct 2021

Mandatory masking resulted in lower rate of COVID-19 infection among school children

A masking mandate in North Carolina schools during the early weeks of the Delta variant surge resulted in a lower rate of infection among school children and staff members than what was reported in the broader community, according to a new report from the ABC Science Collaborative.

11 Oct 2021

Sero-epidemiological insights into pathways to COVID-19 immunity

A new study posted to the medRxiv* server attempts to utilize serology as a tool to identify disparities in infection rates and vaccination coverage.

10 Oct 2021

Research finds different antibody responses following COVID vaccination and natural infection

A new study published in the journal Nature attempted to investigate memory B cell evolution 5 months after vaccination with mRNA vaccines such as Moderna (mRNA-1273) or Pfizer-BioNTech (BNT162b2) in SARS-CoV-2 naïve individuals. The study explored various aspects of memory B cell antibody response like neutralizing response, affinity, epitope targeting, and neutralizing breadth.

10 Oct 2021

The neurological effects of COVID-19

What is the relationship between COVID-19 and the brain? A new review published in Tropical Biomedicine summarizes the key findings on how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe COVID-19 infection, disrupts brain activity and produces a range of long-term neurological disorders.

10 Oct 2021

SARS News and Research

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

Delta SARS-CoV-2 variant does not make kids sicker than Alpha, study finds

Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA

Higher COVID-19 hospitalization and mortality rates reported in rural America

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

An investigation of SARS-CoV-2 infection in diabetic pregnancies

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

COVID-19 aerosol transmission simulation-based risk analysis for in-person learning

A simple method to predict future COVID-19 hospitalization

Researchers discover molecules in the blood that can indicate impending dementia

The role of inhibiting palmitoylation of the SARS-CoV-2 spike protein on viral infectivity

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Prior immunity to influenza, not SARS-CoV-2, prevents severe disease and mortality

Vaccine-induced memory B cells can recognize SARS-CoV-2 variants

Mandatory masking resulted in lower rate of COVID-19 infection among school children

Sero-epidemiological insights into pathways to COVID-19 immunity

Research finds different antibody responses following COVID vaccination and natural infection

The neurological effects of COVID-19

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How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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