Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Dotphoton and Hamamatsu Photonics are partnering to provide the ultimate raw image compression and address the ever-growing biomedical image data volume

Dotphoton, an industry-leading raw image compression company and Hamamatsu Photonics, a world leader in optical systems and photonics manufacturing, are pleased to announce their new partnership.

From Hamamatsu Photonics Europe 26 Apr 2022

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

First product within new ‘in-a-box’ range, which harnesses next-generation, human-relevant Liver-on-a-Chip technology to improve the accuracy and efficiency of NASH drug discovery.

From CN-Bio 26 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Reaction Biology's Novel Approach to Oncology Drug Discovery at AACR Showcase

Reaction Biology, an industry-leading provider of drug discovery services, today announced that twelve abstracts highlighting data from the Company's oncology drug discovery services platform will be presented at the American Association for Cancer Research (AACR) Annual Meeting 2022, held April 8-13, 2022, in New Orleans, Louisiana.

From Reaction Biology Corporation 13 Apr 2022

Epigenetics likely to be the reason why lung cancer patients develop treatment resistance

Doctors typically treat people with nonsmall cell lung cancer, a prevalent and typically incurable type of cancer that makes up 80%-85% of lung cancers, with tyrosine kinase inhibitors, specifically epidermal growth factor receptor inhibitors.

13 Apr 2022

Nemours Children’s Health scientists receive two NIH grants to advance pediatric cancer research

Nemours Children's Health researchers have received two grants from the National Institutes of Health (NIH) totaling $5 million.

12 Apr 2022

Venomtech announces new drug development collaboration with Charles River

Venomtech is collaborating with Charles River Laboratories, International Inc. to help drug developers explore venom-derived compounds for a wide range of therapeutic targets.

12 Apr 2022

Nanocell COVID-19 vaccine elicits potent neutralizing response

A new study describes the high level of neutralizing antibodies elicited by a nanocell vaccine against SARS-CoV-2 in vitro, in vivo, and human studies.

11 Apr 2022

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Researchers identify a potentially effective compound against COVID-19 against the SARS-CoV-2 PLpro.

10 Apr 2022

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

On Thursday, April 7, the Centers for Medicare and Medicaid (CMS) formalized its plan to cover the anti-amyloid drug Aduhelm only for patients enrolled in clinical trials.

8 Apr 2022

Axol Bioscience Raises £3.2 Million GBP (c. $4.2 million USD)

Axol Bioscience Ltd. today announced that it has raised £3.2 million GBP in the extension of its previous funding round, bringing the total raised to £7 million GBP.

From Axol Bioscience Ltd 7 Apr 2022

High-throughput screening assay could identify new prostate cancer drugs

A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer.

6 Apr 2022

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled receptors (GPCRs).

6 Apr 2022

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

For patients with cancer, the tumor-killing power of chemotherapeutic drugs is a double-edged sword. While many cancer drugs kill tumor cells, they can also harm healthy cells as they travel throughout the bloodstream.

6 Apr 2022

Arrayjet introduces Mercury range of next-generation microarray printers

Arrayjet, a leading provider of inkjet liquid-handling solutions, today introduced Mercury, a new core range of five instruments for ultra-low-volume liquid dispensing.

From Arrayjet Ltd 4 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Clinical health outcomes of omicron ‘less severe’ than delta for pediatric patients

New research from the Case Western Reserve University (CWRU) School of Medicine suggests that the children younger than age 5 who are infected with the COVID-19 Omicron variant have less risk of severe health outcomes than those infected with the Delta variant.

2 Apr 2022

Drug Discovery News and Research

Further Reading

Dotphoton and Hamamatsu Photonics are partnering to provide the ultimate raw image compression and address the ever-growing biomedical image data volume

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Reaction Biology's Novel Approach to Oncology Drug Discovery at AACR Showcase

Epigenetics likely to be the reason why lung cancer patients develop treatment resistance

Nemours Children’s Health scientists receive two NIH grants to advance pediatric cancer research

Venomtech announces new drug development collaboration with Charles River

Nanocell COVID-19 vaccine elicits potent neutralizing response

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

Axol Bioscience Raises £3.2 Million GBP (c. $4.2 million USD)

High-throughput screening assay could identify new prostate cancer drugs

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

Arrayjet introduces Mercury range of next-generation microarray printers

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Clinical health outcomes of omicron ‘less severe’ than delta for pediatric patients

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

New tissue-clearing method could speed the study of many disease-related biological processes

Utilizing AI to Accelerate the Field of High Content Analysis

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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