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Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face.

9 May 2018

Centrosome amplification may contribute to initiation of cancers, research suggests

Cells begin to accumulate centrosomes-;organelles that play a vital role during cell division-;before they transform into cancer cells, according to a new study of patients with Barrett's esophagus condition, which is associated with esophageal cancer.

8 May 2018

New microfluidic device captures tumor-specific EVs to guide cancer diagnosis and treatment

Precision cancer treatment relies on obtaining molecular information about the tumor to guide effective treatment decisions.

8 May 2018

Cedars-Sinai study provides new insight into potential negative health effects of air pollution

Prolonged exposure to particulate matter in air pollution in the Los Angeles Basin triggered inflammation and the appearance of cancer-related genes in the brains of rats, a Cedars-Sinai study has found.

8 May 2018

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Neon Therapeutics, a clinical-stage immuno-oncology company developing neoantigen-based therapeutics, today announced that it has treated the first patient in a clinical trial evaluating its proprietary personal neoantigen vaccine, NEO-PV-01, in combination with Merck's anti-PD-1 therapy, KEYTRUDA®, along with chemotherapy.

8 May 2018

Study: Coarse particulate matter in air triggers inflammation and cancer biomarkers in rat brains

8 May 2018

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Cancer is most devastating when it metastasizes--when tumor cells break away, travel through the bloodstream, and then attach elsewhere, only to grow another tumor.

8 May 2018

Study identifies new biomarker for early lung cancer diagnosis

High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.

8 May 2018

FDA grants approval for two drugs administered together to treat aggressive form of thyroid cancer

The U.S. Food and Drug Administration approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has spread to other parts of the body (metastatic), and has a type of abnormal gene, BRAF V600E (BRAF V600E mutation-positive).

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Cancer scientists confirm oligometastasis hypothesis

In 1995, two University of Chicago-based cancer specialists suggested there was an intermediate state -; somewhere between curable localized cancers and lethal widespread disease -; for patients with metastatic cancer.

7 May 2018

Novel 3D cancer model to accelerate development of new and better treatments

A scientist at the University of Virginia School of Medicine, working with local biotech company HemoShear Therapeutics, has created a three-dimensional model of a cancer tumor that he says has the potential to replicate the complex nature and behavior of a real tumor.

7 May 2018

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Castle Biosciences, Inc., the skin cancer diagnostics company providing molecular diagnostics to improve cancer treatment decisions, today announced the presentation of data supporting clinical use of the DecisionDx®-Melanoma test to inform sentinel lymph node biopsy (SLNB) recommendations.

7 May 2018

Parenting concerns affect emotional well-being of mothers with late-stage cancer

Parenting concerns contributed significantly to the psychological distress of mothers with late-stage cancer, according to a study by University of North Carolina Lineberger Comprehensive Cancer Center researchers.

7 May 2018

Researchers uncover protein linked to breast cancer metastasis

Jean-François Côté, a researcher at the Montreal Clinical Research Institute and professor at Université de Montréal's Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive breast cancer.

7 May 2018

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Researchers at Tufts University have elucidated a mechanism by which the "good" bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease.

4 May 2018

Tumor News and Research

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Centrosome amplification may contribute to initiation of cancers, research suggests

New microfluidic device captures tumor-specific EVs to guide cancer diagnosis and treatment

Cedars-Sinai study provides new insight into potential negative health effects of air pollution

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Study: Coarse particulate matter in air triggers inflammation and cancer biomarkers in rat brains

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Study identifies new biomarker for early lung cancer diagnosis

FDA grants approval for two drugs administered together to treat aggressive form of thyroid cancer

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Cancer scientists confirm oligometastasis hypothesis

Novel 3D cancer model to accelerate development of new and better treatments

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Parenting concerns affect emotional well-being of mothers with late-stage cancer

Researchers uncover protein linked to breast cancer metastasis

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Surprising discovery offers new model for studying role of gap junctions in the brain

Stiff tissue can present microenvironment susceptible to tumor growth, says study

Osteoporosis drug prevents spread of basal-like breast cancer in mice

Ocular oncologists link immunotherapy with potentially vision-robbing side effect

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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