Tumor News and Research

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Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

Existing microscopy-based methods of detecting apoptosis, such as TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling), have limited quantitative capabilities due to insufficient signal-to-noise ratios.

19 Apr 2018

The Swedish Childhood Cancer Foundation awards grant to KI researchers

Ten researchers at Karolinska Institutet have been awarded grants in the Swedish Childhood Cancer Foundation's latest call for funding, during which approximately SEK 62 million was allocated.

19 Apr 2018

UT Southwestern scientists discover protein linked to metastatic breast cancer

Researchers at UT Southwestern Medical Center have identified a protein that is strongly associated with metastatic breast cancer and that could be a target for future therapies.

18 Apr 2018

Nanodisc-delivered cancer treatment helps eliminate tumors

In the wrestling match with cancer, chemoimmunotherapy is the new strong arm, and it is building muscle with a nanodisc disguised as "good cholesterol."

18 Apr 2018

Novel method enables fast and noninvasive assessment of tumor status

How aggressive is a tumor? To measure the tumor status without taking tissue samples, Italian researchers have developed a method based on magnetic resonance imaging (MRI) of whole body parts.

18 Apr 2018

High-resolution images of tumor vasculature using new technology

Thanks to a new method of analyzing ultrasound images, conventional scanners can be used for generating high-res images of blood vessels in tumors. This approach makes it easier to distinguish between different types of tumors, and it facilitates the tracking of the progress and success of chemotherapy.

18 Apr 2018

Researchers identify link between physical inactivity and increased risk of dying from cancer

Roswell Park Comprehensive Cancer Center researchers have once again identified a link between physical inactivity and an increased risk of mortality among cancer patients, emphasizing the health risks of a sedentary lifestyle and the importance of regular exercise as therapy for cancer patients both during and after treatment.

18 Apr 2018

Researchers evaluate accuracy of simple blood test to predict lung cancer

Every year, health care providers in the United States discover more than 1.6 million lung nodules in patients.

18 Apr 2018

Researchers use 'top-down proteomics' strategy to get new insights into cancer

When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the "on" position, allowing cells to proliferate uncontrollably.

18 Apr 2018

Researchers clarify immune response for patients with breast cancer brain metastases

Once it has begun to spread in the body, approximately half of patients with an aggressive breast cancer type will develop cancer in the brain. Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center want to improve treatment for patients with breast cancer brain metastases, but using the body's existing defenses - the immune system.

18 Apr 2018

New study maps links between 625 genes and different chemotherapy treatments

Despite the great successes of targeted cancer drugs and the promise of novel immunotherapies, the vast majority of people diagnosed with cancer are still first treated with chemotherapy. Now a new study by UCSF researchers using techniques drawn from computational biology could make it much easier for physicians to use the genetic profile of a patient's tumor to pick the chemotherapy treatment with the fewest side effects and best chance of success.

18 Apr 2018

Roswell Park researchers identify driver of cancer-promoting metabolic changes

Roswell Park Comprehensive Cancer Center researchers have identified a potential key player promoting cancer progression through changes in the cell environment that are conducive to metastasis.

17 Apr 2018

Students develop one-size-fits-all, inexpensive embolization tool

Stemming the flow of blood to starve a tumor or stop hemorrhage can be an expensive, repetitive task for doctors, requiring a variety of approaches and materials for different patients and different sized blood vessels. Often, the interventional radiologists who perform these important procedures must try several times in order to successfully stop the bleeding.

17 Apr 2018

Study reports promising novel approach to treat therapy resistant pediatric brain tumors

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children.

17 Apr 2018

Two immune checkpoint inhibitors efficiently block leukemia development in preclinical tests

Chronic lymphocytic leukemia is a hematological malignancy that originates in the blood-forming cells of the bone marrow and spreads to other organs through the bloodstream.

17 Apr 2018

Study challenges use of whole-brain radiation for small-cell lung cancer patients with brain metastases

Lung cancer often metastasizes to the brain. Historically, brain metastases have been treated with whole-brain radiation therapy.

17 Apr 2018

Researchers discover potential hurdle for personalized medicine

A recent study has shown that loss of the Erk oncogene can stimulate tumorigenesis in cells where Ras has been eliminated. The findings may have important consequences for the development of personalized medicines that target Ras.

17 Apr 2018

MD Anderson research provides insight into memory T cell development and disease relapse

Just like people, some T cells have excellent memories. These subtypes known as memory T cells may explain why some immunotherapies are more effective than others and potentially lead to researchers designing more effective studies using combination checkpoint blockade treatments, according to experts at The University of Texas MD Anderson Cancer Center.

16 Apr 2018

Engineered immune cells clear deadly pediatric brain tumor in mice

Engineered human immune cells can vanquish a deadly pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.

16 Apr 2018

Anti-PD-1 treatment reduces tumor size and post-surgical relapse of lung cancer

A drug given to early stage lung cancer patients before they undergo surgery showed major tumor responses in the removed tumor and an increase in anti-tumor T-cells that remained after the tumor was removed, which resulted in fewer relapse cases in the patients.

16 Apr 2018