Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Researchers uncover new 'hidden' gene in SARS-CoV-2

Researchers have discovered a new "hidden" gene in SARS-CoV-2--the virus that causes COVID-19--that may have contributed to its unique biology and pandemic potential.

10 Nov 2020

SARS-CoV-2 RNA genome structure reveals potential targets for development of drugs

The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University.

10 Nov 2020

WPI researchers awarded NIH funding to develop computational models for human cell division

Two researchers at Worcester Polytechnic Institute have been awarded $917,999 by the National Institutes of Health to develop computational models for the study of a critical piece of cellular machinery that often goes awry in cancer.

9 Nov 2020

New resource can help predict drug sensitivity and optimize therapeutic strategies

Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies.

6 Nov 2020

Antiangiogenic drugs increase the aggressiveness of some kidney tumors

Angiogenesis is the process by which tumors create new blood vessels that will provide them the nutrients to continue growing.

5 Nov 2020

NIH awards grant totaling $19.5M for Down syndrome research project

Scientists and data experts are joining forces to create the world's first centralized platform for Down syndrome researchers to share, access, and analyze data.

5 Nov 2020

Argonne supports the largest analysis of COVID-19 genome sequences in the U.S.

Argonne computational resources supported the largest comprehensive analysis of COVID-19 genome sequences in the U.S. and helped corroborate growing evidence of a protein mutation.

5 Nov 2020

16 new lineages of SARS-CoV-2 emerge in South Africa despite lockdown

Published in a recent medRxiv* paper, researchers from South Africa, the United Kingdom, and Brazil found that these mutations in SARS-CoV-2 lineages are localized to South Africa. These unique strains, not found elsewhere in the world, are thought to have contributed around 42% to the country's total infection rate.

3 Nov 2020

Global collaboration provides a COVID-19 disease map

A collaboration of researchers from 120 different institutes across 30 countries including France, Germany, Australia, Japan, USA, India, Turkey, Brazil, and Canada initiated an effort to develop a COVID-19 Disease Map - a collection of computational models and diagrams of molecular mechanisms implicated in COVID-19.

2 Nov 2020

Study: Toxins produced by tube-dwelling anemones have pharmacological potential

Researchers based in Brazil and the United States have completed the first-ever mapping exercise to profile the toxins produced by tube-dwelling anemones, or cerianthids, a family of marine animals belonging to the same phylum (Cnidaria) as sea anemones, jellyfish and corals.

30 Oct 2020

McLean Hospital joins public-private partnership to find cure for schizophrenia

In September, McLean Hospital joined the National Institutes of Health, the U.S. Food and Drug Administration, and several public and private organizations to find early therapeutic interventions for people at risk for schizophrenia.

29 Oct 2020

Study reveals complex and vast diversity of African genetic variation

The study, in which six Wits researchers were involved, show that these newly discovered variants were found mostly among newly sampled ethnolinguistic groups.

29 Oct 2020

Scientists use experimental approach to identify genes and interactions

A phage is a virus that invades a bacterial cell. While harmless to human cells, phages are potentially deadly to bacteria since many phages enter a cell in order to hijack its machinery in order to reproduce itself, thus destroying the cell.

28 Oct 2020

Study: SARS-CoV-2 virus adopts new strategy to ensure its replication, spread

Since COVID-19 began its menacing march across Wuhan, China, in December 2019, and then across the world, the SARS-CoV-2 virus has taken a "whatever works" strategy to ensure its replication and spread.

27 Oct 2020

Expression of a specific gene could regulate feelings of fear and its extinction

Fear and fear extinction learning are adaptive processes caused by molecular changes in specific brain circuits, and they're perturbed in conditions such as anxiety and post-traumatic stress disorder.

27 Oct 2020

Study analyzes link between clonal hematopoiesis and treatment-related blood cancer risk

In recent years, improvements in cancer therapy have led to a significant increase in cancer survivorship. Experts estimate that by 2022, the United States will have 18 million cancer survivors, but a subset of those survivors will have long-term health problems to be addressed.

27 Oct 2020

Bruker introduces Vutara™ VXL best-in-class super-resolution microscope and spatial biology analysis capabilities

Bruker Corporation today announced the release of the Vutara VXL Super-Resolution Fluorescence Microscope for nanoscale biological imaging. The new system opens an affordable and easy-to-use path for both core facilities and individual investigators to enter the world of super-resolution imaging by incorporating Bruker’s industry-leading single-molecule localization (SML) technology in a streamlined system with compact footprint.

From Bruker Nano Surfaces and Metrology 23 Oct 2020