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NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration.

14 Sep 2022

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

In a new study, researchers investigated the interactions between sirtuin 5 (SIRT5) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein (Nsp14) protein.

14 Sep 2022

Study highlights the efficacy of MVA-BN booster vaccination in inducing durable B cell memory responses against monkeypox

In a new study, researchers assessed the immunogenicity, safety, and booster-efficacy of the Modified Vaccinia virus Ankara-Bavarian Nordic (MVA-BN) vaccine currently being used for immunization against monkeypox.

14 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

Intranasal administration of liposomes displaying SARS-CoV-2 antigen induces mucosal immunity

A new study suggested that an intranasal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine induced mucosal immune responses in mice.

14 Sep 2022

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib remain poorly understood. In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells.

14 Sep 2022

Manuka honey could cure serious lung infections caused by drug-resistant bacterium

In a recent study published in the journal Microbiology, researchers demonstrated that incorporating Manuka honey into nebulized antibiotic treatment could effectively combat respiratory infections due to Mycobacterium abscessusus, offering a novel new therapeutic strategy for M. abscessus management.

13 Sep 2022

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

esearchers measured the monkeypox virus-neutralizing antibodies produced by the vaccinia virus vaccine, modified vaccinia virus Ankara vaccine, and monkeypox virus to understand the efficacy of the MVA-Bavarian Nordic vaccine currently being used against monkeypox.

12 Sep 2022

A direct side-by-side comparison of all available COVID-19 vaccines

In a recent study posted to the medRxiv* preprint server, researchers assessed immune responses to homologous and heterologous coronavirus disease 2019 (COVID-19) vaccine combinations among Córdoba, Spain residents.

11 Sep 2022

All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

Using wastewater-based epidemiology to monitor monkeypox

Monkeypox, a virus that causes painful rashes and flu-like symptoms, is spreading rapidly throughout many parts of the world, including the U.S. To get a fast understanding of how the virus is moving through communities, researchers reporting in ACS' Environmental Science & Technology Letters suggest turning to wastewater epidemiology.

8 Sep 2022

Techniques used for SARS-CoV-2 detection in body fluids

In a recent review published in the journal Trends in Analytical Chemistry, researchers provided a comprehensive overview of the current techniques used for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in bodily fluids.

7 Sep 2022

Plant production of nanobodies that neutralize the interaction between ACE2 receptor and SARS-CoV-2 spike protein

Researchers demonstrated the production of nanobodies against SARS-CoV-2 spike protein.

7 Sep 2022

DNA levels of monkeypox correlate with virus infectivity

Scientists test clinical samples of MPXV patients to determine the relationship between the MPXV DNA copies and infectious status.

6 Sep 2022

Neurological manifestations associated with monkeypox infection

A new study presents current information regarding the neurological presentations and complications of monkeypox infection.

5 Sep 2022

Bringing flexibility to Sanger sequencing and DNA-fragment analysis with the Spectrum Compact CE System

In this interview, News Med is talking to Gabriela Saldanha about DNA Fragmentation and Sanger Sequencing.

From Promega Corporation 5 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences BV 5 Sep 2022

Novel P22-mAb based bELISA assay can help detect antibodies against African swine fever virus

African swine fever (ASF) is a highly infectious and fatal disease of pigs. Due to the complexity of the ASF virus (ASFV) and various clinical forms of the disease, a wide range of highly effective and robust sero-diagnostic assays are required.

2 Sep 2022

The dynamics of neutralizing antibodies in a cohort of children and adolescents after SARS-CoV-2 infection

In a recent JAMA Pediatrics study, scientists analyzed a cohort containing children and adolescents after recovering from COVID-19 to determine the dynamics of neutralizing antibodies.

2 Sep 2022

Symptoms of monkeypox may not always be evident

A recently published article in the journal JAMA Medical News & Perspectives has stated that some monkeypox infections may be asymptomatic or very mildly symptomatic and, thus, can easily remain unnoticed.

1 Sep 2022

Assay News and Research

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

Study highlights the efficacy of MVA-BN booster vaccination in inducing durable B cell memory responses against monkeypox

What is the impact of COVID-19 treatments targeting intracellular Neu1?

Intranasal administration of liposomes displaying SARS-CoV-2 antigen induces mucosal immunity

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

Manuka honey could cure serious lung infections caused by drug-resistant bacterium

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

A direct side-by-side comparison of all available COVID-19 vaccines

All SARS-CoV-2 variants neutralized by a potent new antibody

Using wastewater-based epidemiology to monitor monkeypox

Techniques used for SARS-CoV-2 detection in body fluids

Plant production of nanobodies that neutralize the interaction between ACE2 receptor and SARS-CoV-2 spike protein

DNA levels of monkeypox correlate with virus infectivity

Neurological manifestations associated with monkeypox infection

Bringing flexibility to Sanger sequencing and DNA-fragment analysis with the Spectrum Compact CE System

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Novel P22-mAb based bELISA assay can help detect antibodies against African swine fever virus

The dynamics of neutralizing antibodies in a cohort of children and adolescents after SARS-CoV-2 infection

Symptoms of monkeypox may not always be evident

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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