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Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

The COVID-19 pandemic has claimed over 2.67 million lives in less than a year and a half. However, it is uncommon in children, with less than 2% of the cases being in individuals below the age of 19. Most of these are of mild severity, with the clinical features of severe COVID-19 being rare in this age group.

17 Mar 2021

COVID-19 is more difficult to diagnose in children and adolescents, finds study

The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread to over 192 countries and territories, causing an enormous loss of lives and economic devastation.

17 Mar 2021

Socioeconomic disparities could explain the association of race/ethnicity with worse COVID-19 outcomes

A new study published online in the Annals of the American Thoracic Society reveals how socioeconomic factors partially explain the increased odds that Black and Hispanic Americans have of testing positive for SARS-CoV-2, the virus that causes COVID-19.

17 Mar 2021

New research proposes innovative antibody-based treatment to prevent SARS-CoV-2 viral entry

A brief report by researchers at the University of Virginia, USA, proposes using an antibody-based treatment with a plug-and-play strategy to inhibit the ability of SARS-CoV-2 to invade human cells.

17 Mar 2021

Researchers develop innovative profiling methods for SARS-CoV-2 infection

A team of researchers from various institutions in the USA used RNA-sequencing data and other methods to profile unique genes and other characteristics associated with SARS-CoV-2 in New York City (NYC).

17 Mar 2021

Compromised immunity can allow SARS-CoV-2 to evade the immune system

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity--such as individuals receiving immune-suppressive drugs for autoimmune diseases--can become chronically infected.

17 Mar 2021

Evaluation of Pfizer-BioNTech COVID-19 vaccine among residents of two skilled nursing facilities

The severity of COVID-19 among the residents of long-term care facilities (LTCFs) has been reported to be disproportionately high. Specifically, individuals residing in skilled nursing facilities (SNFs) are found to be the most severely affected, both in terms of morbidity and mortality, and are, thereby, listed for early COVID-19 vaccination. In comparison to the general population, SNF residents are more vulnerable, with a weak immune system.

17 Mar 2021

Living with a COVID-19 case brings worse symptoms and stronger antibody response

This study suggests that high virus exposure levels contribute to greater disease severity and stronger antibody responses. The observations from this study are published on the medRxiv preprint server.

17 Mar 2021

People with high BMI may now receive their COVID-19 vaccine in California

Now, California state allows individuals with one of ten comorbidities to get their COVID-19 jabs. This comes after obesity being tagged as COVID-19 vaccine eligibility.

16 Mar 2021

Testing for mRNA-1283, Moderna's next generation COVID-19 vaccine commences

As vaccine efforts against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease, roll out in various countries, Moderna ups the game by testing its next-generation COVID-19 vaccine.

16 Mar 2021

Salivary IgG to SARS-CoV-2 after mild COVID-19

A team of researchers based in Stockholm, Sweden, has demonstrated that individuals exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have antibodies for the disease up to nine months after acquiring the disease, even if they displayed only mild symptoms.

16 Mar 2021

New Colombian SARS-CoV-2 lineage shares antibody-resistant mutations with other variants

Scientists in Colombia have identified a new highly divergent SARS-CoV-2 lineage with Spike substitutions L249S and E484K. These same mutations have convergently appeared in other mutant strains of the virus, most notably in variants of concern.

16 Mar 2021

SARS-CoV-2 can spread through cold-chain transport

In light of growing evidence, researchers say that SARS-CoV-2 virus transmission via contaminated surfaces, and in particular, frozen foods and products that are transported while keeping them at low temperatures, should be taken into account when devising prevention strategies.

16 Mar 2021

Novel protein construct prevents lethal COVID-19 in mice

Researchers in the United States have developed a novel protein that prevented lethal disease among mice infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

16 Mar 2021

Saliva-based testing as a method for monitoring population immunity to SARS-CoV-2 infection

Researchers in the United States have shown that saliva-based sampling could serve as an accurate and non-invasive alternative to blood sampling for monitoring people’s antibody responses following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or vaccination against the virus.

16 Mar 2021

Researchers uncover potential new target for anti-COVID-19 therapies

Researchers from Cleveland Clinic's Florida Research and Innovation Center have identified a potential new target for anti-COVID-19 therapies.

16 Mar 2021

SARS-CoV-2 Brazilian variant may potentially escape T cell-mediated host immune responses

A team of scientists from Brazil recently explored the abilities of the UK, South African, and Brazilian variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to evade host CD8+ T cell responses induced by natural infection or vaccination. The findings reveal reduced antigenic coverage for the P.2 Brazilian lineage, indicating its ability to evade SARS-CoV-2-induced T cell responses.

16 Mar 2021

Ferret study shows SARS-CoV-2 airborne transmission dynamics

A team of researchers led by Sander Herfst from Erasmus University Medical Center in The Netherlands suggests severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could spread through the air at a one-meter distance and cause infection in a new ferret model study.

16 Mar 2021

SARS-CoV-2 in wastewater may pose risks to marine mammals

Endangered marine mammals — seals, dolphins, whales, and otters — are almost as vulnerable as humans in becoming infected from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Researchers from the Dalhousie University in Canada published a study in Science of The Total Environment that found human wastewater as a potential mode of coronavirus transmission to animals.

16 Mar 2021

Cross-national study associates low vitamin D levels with higher COVID-19-related mortality

A new study by an international team of researchers – from New York University, Abu Dhabi, the Ludwig-Maximilians-Universität, München, and Barts Cancer Institute, London – showed that there are lower COVID-19 mortality rates in countries with the most insufficient annual sun exposure, but highest mean 25-hydroxyvitamin D (25(OH)D) or vitamin D (25)-HD levels.

16 Mar 2021

SARS News and Research

Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

COVID-19 is more difficult to diagnose in children and adolescents, finds study

Socioeconomic disparities could explain the association of race/ethnicity with worse COVID-19 outcomes

New research proposes innovative antibody-based treatment to prevent SARS-CoV-2 viral entry

Researchers develop innovative profiling methods for SARS-CoV-2 infection

Compromised immunity can allow SARS-CoV-2 to evade the immune system

Evaluation of Pfizer-BioNTech COVID-19 vaccine among residents of two skilled nursing facilities

Living with a COVID-19 case brings worse symptoms and stronger antibody response

People with high BMI may now receive their COVID-19 vaccine in California

Testing for mRNA-1283, Moderna's next generation COVID-19 vaccine commences

Salivary IgG to SARS-CoV-2 after mild COVID-19

New Colombian SARS-CoV-2 lineage shares antibody-resistant mutations with other variants

SARS-CoV-2 can spread through cold-chain transport

Novel protein construct prevents lethal COVID-19 in mice

Saliva-based testing as a method for monitoring population immunity to SARS-CoV-2 infection

Researchers uncover potential new target for anti-COVID-19 therapies

SARS-CoV-2 Brazilian variant may potentially escape T cell-mediated host immune responses

Ferret study shows SARS-CoV-2 airborne transmission dynamics

SARS-CoV-2 in wastewater may pose risks to marine mammals

Cross-national study associates low vitamin D levels with higher COVID-19-related mortality

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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