Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Method to propagate mouse brain stem cells derived from ES cells

It's hard to grow stem cells in a dish. In particular, while it is possible to multiply mouse embryonic stem cells in culture, propagating stem cells that are specific to distinct tissues (e.g. neural stem cells) has proven to be a challenge.

16 Aug 2005

Key toxin could provide for world's first treatment for Alzheimer's

Dr Karen Cullen at Sydney University’s Institute for Biomedical Research is part of a collaborative team which has identified a key component in the progression of Alzheimer’s disease, a finding which may produce the world’s first effective treatment to combat the debilitating effects of the disease.

15 Aug 2005

Folates best at preventing Alzheimer's disease

According to results from a long-term study on aging, adults who eat the daily recommended allowance of folates significantly reduce their risk of developing Alzheimer's disease.

15 Aug 2005

Vitamin B reduces risk of developing Alzheimer's disease

Adults who eat the daily recommended allowance of folates - B-vitamin nutrients found in oranges, legumes, leafy green vegetables and folic acid supplements - significantly reduce their risk of developing Alzheimer's disease, according to results from a long-term National Institute on Aging study of diet and brain aging.

13 Aug 2005

Key step in the production of beta-amyloid

Researchers at UT Southwestern Medical Center have defined a key step in the production of beta-amyloid, a short protein that is thought to be responsible for the development of Alzheimer's disease. Understanding this step may aid in the discovery of drugs that could help block the disease from developing.

11 Aug 2005

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer's disease

Alzheimer disease (AD) is the most common form of senile dementia, with no effective treatment available. In a study appearing online on August 11 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Howard Weiner and colleagues from Harvard describe a novel immunologic approach for the treatment of AD.

11 Aug 2005

Early detection of Alzheimer's coming soon?

Alzheimer's disease is the most common form of old-age dementia and has become the fourth most common cause of death in the USA. The cause of the disease is protein deposits, called amyloid plaques, in the brain.

11 Aug 2005

High insulin levels increase inflammatory markers and beta-amyloids

Moderately elevated levels of insulin increase the levels of inflammatory markers and beta-amyloid in plasma and in cerebrospinal fluid, and these markers may contribute to Alzheimer's disease, according to a new study posted online today from Archives of Neurology, one of the JAMA/Archives journals.

9 Aug 2005

Australian researchers have found a toxin that plays an important role in the progression of Alzheimer's disease

The research, which is led by two University of New South Wales academics, is significant because drugs that are in the advanced developmental phase for other conditions might be able to be used on Alzheimer's patients, to halt the disease progressing.

4 Aug 2005

Early warning aigns of Alzheimer's show up across cognitive areas years before official diagnosis

By combing through dozens of Alzheimer's disease (AD) studies, psychologists have gained a clear picture of cognitive problems in people who will develop the degenerative brain disease.

4 Aug 2005

Breakthrough in Alzheimer's research

This week scientists of the Flanders Interuniversity Institute for Biotechnology (VIB) will once again publish a breakthrough in their research regarding Alzheimer's disease.

3 Aug 2005

Living Cell Technologies announces results for treating Huntington's disease

Living Cell Technologies announced pre-clinical results today showing its brain protection product, NeurotrophinCell (NtCell) produces a marked reduction in the size of brain lesions in a Huntington's disease (HD) model.

2 Aug 2005

People have signs of Alzheimer's years before diagnosis

Psychologists say that after examining dozens of Alzheimer's studies, they now have a clear picture of the cognitive problems which will develop in people with the degenerative brain disease.

1 Aug 2005

People can show early warning signs of Alzheimer's disease years before they are officially diagnosed

By combing through dozens of Alzheimer's disease (AD) studies, psychologists have gained a clear picture of cognitive problems in people who will develop the degenerative brain disease.

1 Aug 2005

New research says binge before bedtime and shed weight!

According to new research, dieters who binge before bedtime could hold the key to weight loss.

29 Jul 2005

Anti-inflammatory function of Alzheimer's disease drugs revealed

The mechanism in anti-Alzheimer's disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been revealed by researchers at the Hebrew university of Jerusalem.

28 Jul 2005

New breakthrough on the origins of Alzheimer's disease

Scientists from the Flanders Interuniversity Institute for Biotechnology (VIB) associated with the University of Antwerp have achieved a new breakthrough in their research on the origins of Alzheimer's disease.

27 Jul 2005

Adding spectroscopy to breast MR examinations may improve the efficiency and quality of patient care

Measuring the biochemical changes in breast tumors with magnetic resonance (MR) spectroscopy enables radiologists to more accurately distinguish benign tumors from cancerous ones, according to a study appearing in the August issue of the journal Radiology.

26 Jul 2005

Plaques in the brain more likely to be expressed as dementia in women than in men

Researchers from the Rush Alzheimer's Disease Center found that plaques and tangles in the brain, the changes seen in people with Alzheimer's disease (AD), are more likely to be expressed as dementia in women than in men.

25 Jul 2005

U.S. scientists find 3 molecules that could help fight Alzheimer's

A team of scientists at the Neuroscience Research Institute at the University of California, Santa Barbara, say they have identified three molecules that appear to stop a key culprit behind Alzheimer's disease.

25 Jul 2005