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Portuguese researcher to earn Bill & Melinda Gates Foundation award for new HIV therapy

João Gonçalves, from Faculdade de Farmácia e Instituto de Medicina Molecular, Lisbon, Portugal, to win a Grand Challenges Exploration Award

29 Apr 2011

Researchers develop new gene therapy technique for CGD treatment

Researchers have developed an effective technique that uses gene therapy on stem cells to correct chronic granulomatous disease in cell culture, which could eventually serve as a treatment for this rare, inherited immune disorder, according to a study published in Blood, the Journal of the American Society of Hematology.

29 Apr 2011

DNA structure co-discoverer to present 'Curing Incurable Cancer' at Uofl event

James D. Watson, Ph.D., winner of the 1962 Nobel Prize with Francis Crick and Maurice Wilkins for the discovery of the double helical structure of DNA, will present "Curing Incurable Cancer" and attend other events associated with the Kentucky Derby. Watson's appearances are sponsored by the James Graham Brown Cancer Center at the University of Louisville.

28 Apr 2011

Researchers identify three enterotypes in human intestinal bacteria

It would appear that in terms of composition, the intestinal bacteria of every individual can be divided into three main groups known as enterotypes. The intestinal bacteria in each enterotype organise themselves into distinct, stable clusters displaying common features.

28 Apr 2011

Researchers begin approved drugs screening for clinical use against rare diseases

Researchers have begun screening the first definitive collection of thousands of approved drugs for clinical use against rare and neglected diseases. They are hunting for additional uses of the drugs hoping to find off-label therapies, for some of the 6,000 rare diseases that afflict 25 million Americans.

28 Apr 2011

MIT develops new software to predict complex 3-D DNA structures

While the primary job of DNA in cells is to carry genetic information from one generation to the next, some scientists also see the highly stable and programmable molecule as an ideal building material for nanoscale structures that could be used to deliver drugs, act as biosensors, perform artificial photosynthesis and more.

28 Apr 2011

New study reveals a novel gene linked with major depression

A new study reveals a novel gene associated with major depression. The research, published by Cell Press in the April 28 issue of the journal Neuron, suggests a previously unrecognized mechanism for major depression and may guide future therapeutic strategies for this debilitating mood disorder.

28 Apr 2011

Affymetrix reports total revenue of $73.7 million for first quarter 2011

Affymetrix, Inc., today reported its operating results for the first quarter of 2011. Total revenue for the quarter was $73.7 million, as compared to total revenue of $80.2 million in the first quarter of 2010.

28 Apr 2011

New study sheds light on evolution of 2009 pandemic influenza A(H1N1) virus in Japan

Analysis of mutations of the 2009 pandemic influenza A(H1N1) virus by researchers at the RIKEN Omics Science Center (OSC) has revealed major genetic differences between the virus in its early phase of infection in Japan and in its peak phase. While yielding valuable clues on the genetic origins of drug resistance, the findings also pave the way toward the development of new diagnostic kits for detecting and preventing the spread of global pandemic diseases.

26 Apr 2011

BIOBASE introduces new genome sequence custom annotation tool

BIOBASE announced its launch of a new custom annotation tool designed to aid in functional annotation of next generation sequences from uncharacterized genomes.

26 Apr 2011

DNA rearrangements in roundworm chromosomes offer insight into genome duplications in developing tumors

A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors.

22 Apr 2011

Scientists decode entire genome of lyre-leaved rock cress

It would appear reasonable to assume that two closely related plant species would have similar genetic blueprints. However, scientists from the Max Planck Institute for Developmental Biology in T-bingen, working in cooperation with an international research team have now decoded, for the first time, the entire genome of the lyre-leaved rock cress (Arabidopsis lyrata), a close relative of the thale cress (Arabidopsis thaliana), the model plant used by geneticists.

22 Apr 2011

US-LACRN selects Agilent gene expression microarrays for major breast cancer study

Agilent Technologies Inc. today announced that the United States-Latin American Cancer Research Network has selected Agilent Gene Expression microarrays and associated instruments for a major study of breast cancer in five Latin American nations.

21 Apr 2011

Nutlin-3a molecules stimulate signal to induce cell death and senescence in brain cancer

Researchers of Apoptosis and Cancer Group of the Bellvitge Biomedical Research Institute (IDIBELL) have found that a small molecule, Nutlin-3a, an antagonist of MDM2 protein, stimulates the signalling pathway of another protein, p53.

21 Apr 2011

Penn researchers explore the role of telomere caps in human aging

Researchers at the University of Pennsylvania School of Medicine are delving into the details of the complex structure at the ends of chromosomes.

21 Apr 2011

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

Two new studies highlight the power of sequencing cancer patients' genomes as a diagnostic tool, helping doctors decide the best course of treatment and researchers identify new cancer susceptibility mutations that can be passed from parent to child.

20 Apr 2011

Consumers decide to use mail-in genetic tests based on rational and emotional reasons

Consumers decide whether to use mail-in genetic tests based on both rational and emotional reasons, a finding that adds to a growing body of health-care behavior research on information seeking and avoidance, according to researchers at the University of California, Riverside.

20 Apr 2011

Whole-genome sequencing could soon improve cancer survival rates

Cancer survival rates could improve soon with whole-genome sequencing, according to two studies published in the April 20, 2011, issue of the Journal of the American Medical Association that describe the first clinical applications of the high-tech process in patients with cancer.

20 Apr 2011

New method allows single microchip to screen tens of thousands of genes simultaneously

RNA interference technology, which is used in cell biology, has revolutionised functional research of the gene products in the last ten years. VTT Technical Research Centre of Finland has developed a method which allows a single microchip to be used to screen the functions of tens of thousands of genes simultaneously by means of RNA interference.

20 Apr 2011

Gene mutation in Tibetian Terrier dogs causes hereditary form of Parkinson's disease in humans

University of Missouri researchers believe both man and animal will benefit from their discovery that the same gene mutation found in Tibetan Terrier dogs can also be found in a fatal human neurological disorder related to Parkinson's disease.

19 Apr 2011

Genome News and Research

Portuguese researcher to earn Bill & Melinda Gates Foundation award for new HIV therapy

Researchers develop new gene therapy technique for CGD treatment

DNA structure co-discoverer to present 'Curing Incurable Cancer' at Uofl event

Researchers identify three enterotypes in human intestinal bacteria

Researchers begin approved drugs screening for clinical use against rare diseases

MIT develops new software to predict complex 3-D DNA structures

New study reveals a novel gene linked with major depression

Affymetrix reports total revenue of $73.7 million for first quarter 2011

New study sheds light on evolution of 2009 pandemic influenza A(H1N1) virus in Japan

BIOBASE introduces new genome sequence custom annotation tool

DNA rearrangements in roundworm chromosomes offer insight into genome duplications in developing tumors

Scientists decode entire genome of lyre-leaved rock cress

US-LACRN selects Agilent gene expression microarrays for major breast cancer study

Nutlin-3a molecules stimulate signal to induce cell death and senescence in brain cancer

Penn researchers explore the role of telomere caps in human aging

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

Consumers decide to use mail-in genetic tests based on rational and emotional reasons

Whole-genome sequencing could soon improve cancer survival rates

New method allows single microchip to screen tens of thousands of genes simultaneously

Gene mutation in Tibetian Terrier dogs causes hereditary form of Parkinson's disease in humans

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