SARS CoV 2 News and Research

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Case Western Reserve researchers receive $2.3 million to study COVID-19 spread in nursing homes

Almost from the moment COVID-19 reached this nation's shores, nursing homes have experienced some of its most devastating effects.

28 Sep 2020

Genetic mutations hinder immune response in severe COVID-19

Now, a truly international team of nearly 140 researchers aimed to determine why some people develop severe illness when once infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19 disease.

28 Sep 2020

Auto-antibodies may explain why some people develop severe COVID-19

Now, a new study by an international team of health experts shows that some life-threatening cases of COVID-19 can be traced to specific weak spots in the patients' immune system.

28 Sep 2020

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

The vaccine candidate produced a high level of neutralizing antibodies in animal models. Rhesus macaques immunized with the vaccine candidate showed reduced viral loads in the lungs. The research is published on the preprint server bioRxiv.

28 Sep 2020

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Now in new research published on the preprint server bioRxix*, a novel formulation of the drug Niclosamide (NIC) is observed to be effective against SARS-CoV-2 and MERS-CoV in mouse models; it also protects against methicillin-resistance Staphylococcus aureus pneumonia and inflammatory lung damage.

28 Sep 2020

Seniors the optimal target for SARS-CoV-2 vaccination

ith several vaccines already in stage 3 clinical trials, a study by University of Warwick researchers and published on the preprint server medRxiv in September 2020 discusses the use of computer modeling techniques in order to achieve optimal vaccine coverage.

28 Sep 2020

Inhaled corticosteroids may not increase COVID-19 mortality

Inhaled corticosteroids (ICS) are the first line of treatment to counter the inflammatory pathology in several conditions, including asthma and chronic obstructive pulmonary disease (COPD). Now, a new study published in the journal The Lancet Respiratory Medicine in September 2020 reports on the actual role of ICS in reducing COVID-19 mortality.

28 Sep 2020

Anti-N-protein IgG may predict severity of COVID-19

A recent study by researchers at the University of Miami, Miami VA Healthcare System and Express Gene and published on the preprint server medRxiv in September 2020 reports on the prognostic significance of the anti-N Immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Sep 2020

Risk factors for mortality among hospitalized patients with COVID-19

A new study by scientists at biotechnology company Genentech, Inc., and published on the preprint server medRxiv in September 2020 attempts to identify the factors which may shape the risk for death in COVID-19 disease.

27 Sep 2020

CRISPR screening identifies human host pathways that facilitate coronavirus infection

The human coronavirus family consists of 7 known pathogens, for which there are no approved vaccines or specific therapeutic options. Although the seasonal human coronaviruses - OC43, HKU1, 229E, and NL63 – only cause mild respiratory infections, three highly pathogenic coronaviruses that emerged in the last two decades revealed the pandemic potential of this family of viruses.

27 Sep 2020

Young adults now driving force behind the ongoing COVID-19 pandemic says CDC

The Centers for Disease Control and Prevention (CDC) has released a report stating that the ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is on the rise among young adults and this rise is preventing the pandemic from abating.

27 Sep 2020

College re-openings could cause 3,200 extra cases of COVID-19 per day in the US

A new report published in the preprint server medRxiv in September 2020 shows the close relationship between the re-opening of colleges, especially those drawing students from high-incidence areas, and those offering in-person instruction, and the significant increase in the incidence of COVID-19 among students and the community.

27 Sep 2020

Bacteria-free method for making SARS-CoV-2 infectious clones

Using a circular polymerase chain reaction, researchers have developed a method for making severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recombinant virus, with the ability to introduce mutations. The research by Japanese scientists is published on the preprint server bioRxiv* in September 2020.

27 Sep 2020

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

A multinational research group recently published a paper in the journal Lancet Respiratory Medicine which describes the first patient with a severe form of coronavirus disease (COVID-19) that was successfully treated with human recombinant soluble ACE2.

27 Sep 2020

Complex SARS-CoV-2 serology means universal immunological assay is not feasible

As we improve our understanding of immune responses and correlates of protection against the severe acute respiratory syndrome coronavirus (SARS-CoV-2), two UK researchers emphasize that we will probably utilize different assays to tackle specific questions. Their commentary is published in the prestigious journal Lancet Infectious Diseases.

27 Sep 2020

Yale designates three independent laboratories to perform SalivaDirect COVID-19 test

Yale has designated three independent laboratories to perform the university-developed SalivaDirectTM COVID-19 test.

26 Sep 2020

Combination of heat and high relative humidity can disinfect N95 mask materials

As the COVID-19 pandemic swept around the world early this year, shortages of protective equipment such as N95 masks left healthcare workers little choice but to reuse the masks they had - increasing the risk of infection for both them and their patients.

26 Sep 2020

SARS CoV 2 News and Research

Case Western Reserve researchers receive $2.3 million to study COVID-19 spread in nursing homes

Genetic mutations hinder immune response in severe COVID-19

Auto-antibodies may explain why some people develop severe COVID-19

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Seniors the optimal target for SARS-CoV-2 vaccination

Inhaled corticosteroids may not increase COVID-19 mortality

Anti-N-protein IgG may predict severity of COVID-19

Risk factors for mortality among hospitalized patients with COVID-19

CRISPR screening identifies human host pathways that facilitate coronavirus infection

Young adults now driving force behind the ongoing COVID-19 pandemic says CDC

College re-openings could cause 3,200 extra cases of COVID-19 per day in the US

Bacteria-free method for making SARS-CoV-2 infectious clones

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

Complex SARS-CoV-2 serology means universal immunological assay is not feasible

Yale designates three independent laboratories to perform SalivaDirect COVID-19 test

Combination of heat and high relative humidity can disinfect N95 mask materials

Mask-wearing, handwashing, and social distancing protect against COVID-19, confirms study

Shorter time from COVID-19 symptom onset to hospitalization linked to disease severity, death

SARS-CoV-2 emergence linked with decrease in circulation of common respiratory viruses

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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